Abstract: An example technique for image analysis is provided. An example image analysis method includes obtaining an instructive sequence descriptive of an instructive query, an instructive response, and an instructive trace of intermediate states from the instructive query to the instructive response. The example image analysis method includes inputting, to a machine-learned model, the instructive sequence and an operative image processing query that comprises image data, wherein the machine-learned model is configured to process the operative query with attention over the instructive sequence. The example method can include generating, using the machine-learned model and responsive to the operative query, an operative image processing response that comprises an analysis of the image data.

Abstract: An example method for training a machine-learned sequence processing model includes obtaining a plurality of training examples for training the machine-learned sequence processing model. For each respective training example of the plurality of training examples, the example method includes: obtaining a respective query associated with the respective training example; inputting the respective query to the machine-learned sequence processing model; obtaining, from the machine-learned sequence processing model a response to the respective query and a trace of intermediate states from the respective query to the response; evaluating the response using a ground truth response associated with the respective training example; evaluating the trace using a ground truth trace associated with the respective training example; and updating one or more parameters of the machine-learned sequence processing model based on the evaluation of the response and based on the evaluation of the trace.

Abstract: Example embodiments of aspects of the present disclosure provide an example computer-implemented method for improved prompting of a machine-learned model. The example method can include obtaining an instructive sequence descriptive of an instructive query, an instructive response, and an instructive trace of intermediate states from the instructive query to the instructive response. The example method can include inputting, to a machine-learned model, the instructive sequence and an operative query, wherein the machine-learned model is configured to process the operative query with attention over the instructive sequence. The example method can include generating, using the machine-learned model and responsive to the operative query, an operative response.

Abstract: An example method for pretraining a machine-learned model is provided. The example method includes obtaining a plurality of different combinations of configuration parameters of a pretraining objective framework. The example method includes generating, using the pretraining objective framework, a plurality of corrupted training examples from one or more training examples, wherein the plurality of corrupted training examples are respectively generated according to the plurality of different combinations. The example method includes inputting the plurality of corrupted training examples into the machine-learned model, wherein the machine-learned model is configured to generate uncorrupted subportions corresponding to corrupted subportions of the corrupted training examples. The example method includes obtaining, from the machine-learned model, a plurality of outputs respectively generated by the machine-learned model based on the plurality of corrupted training examples.

Abstract: Systems and methods of the present disclosure are directed to a computer-implemented method. The method can include obtaining a machine-learned model comprising a plurality of model units, wherein each model unit comprises a plurality of parameters that are tied to a shared plurality of parameters. The method can include performing a first plurality of training iterations with the machine-learned model to adjust parameters of the shared plurality of parameters. The method can include detecting, based on the first plurality of training iterations, an occurrence of an untying condition. The method can include untying the parameters of one or more model units from the shared plurality of parameters. The method can include performing a second plurality of training iterations with the machine-learned model to adjust parameters of the one or more model units independent of the shared plurality of parameters.

Abstract: A system associated with quantifying a density level of tumor-infiltrating lymphocytes, based on prediction of reconstructed TIL information associated with tumoral tissue image data during pathology analysis of the tissue image data is disclosed. The system receives digitized diagnostic and stained whole-slide image data related to tissue of a particular type of tumoral data. Defined are regions of interest that represents a portion of, or a full image of the whole-slide image data. The image data is encoded into segmented data portions based on convolutional autoencoding of objects associated with the collection of image data. The density of tumor-infiltrating lymphocytes is determined of bounded segmented data portions for respective classification of the regions of interest. A classification label is assigned to the regions of interest. It is determined whether an assigned classification label is above a pre-determined threshold probability value of lymphocyte infiltrated.

Abstract: A system associated with quantifying a density level of tumor-infiltrating lymphocytes, based on prediction of reconstructed TIL information associated with tumoral tissue image data during pathology analysis of the tissue image data is disclosed. The system receives digitized diagnostic and stained whole-slide image data related to tissue of a particular type of tumoral data. Defined are regions of interest that represents a portion of, or a full image of the whole-slide image data. The image data is encoded into segmented data portions based on convolutional autoencoding of objects associated with the collection of image data. The density of tumor-infiltrating lymphocytes is determined of bounded segmented data portions for respective classification of the regions of interest. A classification label is assigned to the regions of interest. It is determined whether an assigned classification label is above a pre-determined threshold probability value of lymphocyte infiltrated.