Patents by Inventor Le Li

Le Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250145666
    Abstract: The present disclosure relates to cyclic oligopeptides that bind to interleukin-13 (IL-13) which are useful therapeutically in methods of treating or preventing IL-13-associated skin disorders or conditions. The present disclosure also provides methods to treat or prevent IL-13-associated skin disorders or conditions with the IL-13-binding cyclic oligopeptides. The present disclosure further provides methods to produce the IL-13-binding cyclic oligopeptides.
    Type: Application
    Filed: November 19, 2024
    Publication date: May 8, 2025
    Inventors: Xuefei Bai, Sheng Lin, Le Li
  • Publication number: 20250141252
    Abstract: An energy storage converter and an energy storage system are provide. The energy storage converter includes: a DC switching power supply circuit configured to provide a first power supply using DC power from the DC side port; an AC switching power supply circuit configured to provide a second power supply using AC power from the AC side port; a power supply circuit configured to supply power to the energy storage converter using the first power supply or the second power supply; and a control circuit configured to, based on an operation state of the energy storage converter, control the DC switching power supply circuit or the AC switching power supply circuit to provide the power supply circuit with power supply. A power supply mode is selected based on an operation state of the energy storage converter. The DC/AC switching power supply circuit independently supplies power at the same time.
    Type: Application
    Filed: October 30, 2024
    Publication date: May 1, 2025
    Inventors: Hao DONG, Kai DENG, Le LI, Feiyang ZHENG
  • Patent number: 12279531
    Abstract: An alginate hydrogel-based thin-film heat flux sensor for billet crystallizer includes an alginate hydrogel substrate. The alginate hydrogel substrate is configured in a U-shaped planar structure. The U-shaped planar structure includes a first side and a second side, and the first side is longer than the second side. An inner surface of the alginate hydrogel substrate is provided with a first film thermocouple and a second film thermocouple. The first film thermocouple is in crosslinking connection with the second film thermocouple.
    Type: Grant
    Filed: October 16, 2023
    Date of Patent: April 15, 2025
    Assignee: Xi'an Jiaotong University
    Inventors: Zhongkai Zhang, Jiaming Lei, Le Li, Shuimin Li, Bian Tian, Libo Zhao, Zhuangde Jiang
  • Publication number: 20250102595
    Abstract: A fault detection method and a fault protection method for a power conversion system, and a power conversion system are provided, which relate to the technical field of fault detection for circuits. The fault detection method includes: controlling, when the power conversion system operates in a reactive mode, an alternating current pre-charge power supply to operate to charge a bus capacitor of the power conversion system, where the bus capacitor supplies power to a digital signal processor (DSP) through a first switch power supply (SPS), determining whether the DSP is energized to obtain a first determination result, and determining that the bus capacitor is short-circuited if the first determination result indicates that the DSP is de-energized. According to the present disclosure, when the bus capacitor of the power conversion system is short-circuited, the short-circuit fault of the bus capacitor can be detected.
    Type: Application
    Filed: August 21, 2024
    Publication date: March 27, 2025
    Applicant: Sungrow Power Supply Co., Ltd.
    Inventors: Feiyang Zheng, Kai Deng, Le Li
  • Publication number: 20250092146
    Abstract: Disclosed herein, in certain embodiments, are anti-hCCR8 antibodies, anti-hCCR8 antibody conjugates, and pharmaceutical compositions which comprise the anti-hCCR8 antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-hCCR8 antibody described herein, and methods of treatment with use of an anti-hCCR8 antibody described herein.
    Type: Application
    Filed: April 26, 2024
    Publication date: March 20, 2025
    Inventors: Alexander Alexandrov, Karen Chiang, Le Li, Roberto Jappelli, Christopher Roth, Mauro Mileni, Michael Hanson
  • Publication number: 20250078885
    Abstract: A memory device includes a memory array, a first latch and a first logic element. The memory array is configured to operate according to a first global write signal. The first latch is configured to generate a first latch write data based on a clock signal. The first logic element is configured to generate the first global write signal based on the clock signal and the first latch write data.
    Type: Application
    Filed: November 15, 2024
    Publication date: March 6, 2025
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., TSMC NANJING COMPANY LIMITED, TSMC CHINA COMPANY LIMITED
    Inventors: He-Zhou WAN, Xiu-Li YANG, Pei-Le LI, Ching-Wei WU
  • Patent number: 12236712
    Abstract: A facial expression recognition method includes extracting a first feature from color information of pixels in a first image, and extracting a second feature of facial key points from the first image. The method further includes combining the first feature and the second feature, to obtain a fused feature, and determining, by processing circuitry of an electronic device, a first expression.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: February 25, 2025
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Yanbo Fan, Yong Zhang, Le Li, Baoyuan Wu, Zhifeng Li, Wei Liu
  • Publication number: 20250054808
    Abstract: A SOI substrate and a method of manufacturing a SOI substrate are provided. The method includes: providing a device wafer; wherein the device wafer includes a substrate, a buried oxide layer, and a semiconductor layer; the substrate has a first surface and a second surface opposite to the first surface; the buried oxide layer and the semiconductor layer are disposed sequentially on the first surface of the substrate; processing the substrate from the second surface of the substrate to sequentially form an insulating dielectric layer and an electrostatic adsorption layer; wherein a resistivity of the electrostatic adsorption layer is less than a resistivity of the substrate. The SOI substrate takes the electrostatic adsorption layer to perform electrostatic adsorption, difficulties of the SOI substrate performing the electrostatic adsorption are solved.
    Type: Application
    Filed: November 30, 2023
    Publication date: February 13, 2025
    Inventors: Guangjie XUE, Le LI, Jun ZHOU
  • Patent number: 12180307
    Abstract: The present disclosure relates to cyclic oligopeptides that bind to interleukin-13 (IL-13) which are useful therapeutically in methods of treating or preventing IL-13-associated skin disorders or conditions. The present disclosure also provides methods to treat or prevent IL-13-associated skin disorders or conditions with the IL-13-binding cyclic oligopeptides. The present disclosure further provides methods to produce the IL-13-binding cyclic oligopeptides.
    Type: Grant
    Filed: June 13, 2023
    Date of Patent: December 31, 2024
    Assignee: B.A.I. Laboratories, LLC
    Inventors: Xuefei Bai, Sheng Lin, Le Li
  • Patent number: 12176062
    Abstract: A memory device includes a memory array, a first latch and a first logic element. The memory array is configured to operate according to a first global write signal. The first latch is configured to generate a first latch write data based on a clock signal. The first logic element is configured to generate the first global write signal based on the clock signal and the first latch write data.
    Type: Grant
    Filed: June 16, 2023
    Date of Patent: December 24, 2024
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., TSMC NANJING COMPANY LIMITED, TSMC CHINA COMPANY LIMITED
    Inventors: He-Zhou Wan, Xiu-Li Yang, Pei-Le Li, Ching-Wei Wu
  • Publication number: 20240319406
    Abstract: The present disclosure presents a device and method for monitoring and early warning of information perception regarding urban yellow mud water, featuring a rainfall collecting component, a video shooting component, a sediment content monitoring component, a water level monitoring component and a main controller. The video shooting component evaluates the long-term trend of yellow mud water production in a monitoring area by analyzing the color depth of captured water flow, sediment content in the pipeline's flow section, and meteorological rainfall data from the rainfall collecting component. Utilizing data on color, sediment content, flow section, and rainfall, this system achieves unsupervised real-time monitoring and precise early warning for yellow mud water. It provides a scientific basic for traceability, dynamic monitoring, and address challenges such as low measurement accuracy and omitted applicability found in existing methods.
    Type: Application
    Filed: March 21, 2024
    Publication date: September 26, 2024
    Inventors: Shunchao Yu, Xuebing Jiang, Qingbin Pan, Hao Li, Jun Huang, Juan Wang, Le Li, Liping Lin, Guangyan Wu, Xiaolin Liu, Wenfeng Pan, Xinyue Kou, Bin Yin, Zhou Xu, Bin Liu, Qing Liu, Huiqiang Wang
  • Publication number: 20240315184
    Abstract: An SNP molecular marker combination of Brassica napus L. and application method thereof are provided, and the SNP molecular marker combination includes 1407 SNP molecular markers. A set of 1407 high-quality and highly polymorphic SNP markers is screened, which are co-dominant markers, have high specificity, sensitivity and resolution, and have wide application universality. The markers are not affected by environmental conditions and can be detected by using seeds or any type of plant tissue. Detection results are accurate and have good repeatability and stability. Different data results obtained from different testing laboratories can be compared and verified with each other, and the data has universal comparability. A 1.5 K SNP chip is prepared by using the 1407 SNP markers, so as to detect genome-wide SNP of Brassica napus L. samples quickly, with high-throughput and low-cost, which can be effectively used for breeding or assisted breeding of Brassica napus L.
    Type: Application
    Filed: May 3, 2024
    Publication date: September 26, 2024
    Inventors: Zhongsong Liu, Le Li, Hao Chen, Liu Yang, Lei Kang, Lunwen Qian, Gang Xiao, Tailong Tan, Zhenqian Zhang, Yuting Lei, Bingchuan Tian
  • Patent number: 12094704
    Abstract: A semiconductor device and a method of fabricating the semiconductor device are disclosed. The method includes: providing a device wafer and a carrier wafer, the device wafer including an SOI substrate comprising, stacked from the bottom upward, a lower substrate, a buried insulator layer and a semiconductor layer; bonding the device wafer at a front side thereof to the carrier wafer; removing at least the lower substrate through thinning the device wafer from a backside thereof, wherein the backside of the device wafer opposes the front side thereof; and providing a high-resistance substrate and bonding the device wafer at the backside thereof to the high-resistance substrate, the high-resistance substrate having a resistivity higher than that of the lower substrate. With the present disclosure, lower signal loss and improved signal linearity can be achieved while avoiding a significant cost increase.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: September 17, 2024
    Assignee: WUHAN XINXIN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Le Li, Jun Zhou, Sheng Hu
  • Publication number: 20240177148
    Abstract: The present invention discloses a method for generating keys and signatures based on multi-party calculation, and relates to the technical field of MPC the algorithm steps. The method for generating the keys and the signatures based on the multi-party calculation includes: generating public keys and sending a request for generating the public keys to the background of Party 0; performing collaborative calculation by Party 0 and Party 1 to obtain public keys through communication; and returning calculation results to a client by Party 0. By the multi-party calculation method, a wallet owner can sign by the keys, and whether a message is signed by the wallet owner through the public keys of a wallet can be verified through the public keys of the wallet.
    Type: Application
    Filed: November 28, 2022
    Publication date: May 30, 2024
    Inventor: LE LI
  • Publication number: 20240170628
    Abstract: The present disclosure provides a light-emitting substrate and a manufacturing method thereof, a backlight and a display device. The light-emitting substrate includes a substrate including a plurality of light-emitting regions arranged in an array, each of the plurality of light-emitting regions including a driving circuit and at least one light-emitting unit connected to the driving circuit, a first electrically conductive portion on the substrate and connected to the driving circuit and the at least one light-emitting unit in each light-emitting region, and a second electrically conductive portion on the substrate and including a plurality of pads. The first electrically conductive portion and the second electrically conductive portion are on a same layer.
    Type: Application
    Filed: July 30, 2021
    Publication date: May 23, 2024
    Inventors: Chunjian LIU, Wei HAO, Zouming XU, Jian TIAN, Xintao WU, Jie LEI, Jie WANG, Jianying ZHANG, Wenjin FAN, Jiawei XU, Le LI, Jian ZHANG
  • Publication number: 20240170549
    Abstract: A semiconductor device and a fabrication method of the semiconductor device are disclosed. The semiconductor device includes an SOI substrate including a lower substrate, a buried insulating layer and a semiconductor layer; a gate electrode layer formed on the semiconductor layer, the gate electrode layer including a main gate and an extended gate including a first portion joined to the main gate and a second portion located on the side of the first portion away from the main gate; a source region and a drain region, formed in the semiconductor layer respectively on opposing sides of the main gate, the second portion having a length smaller than a length of the first portion on the semiconductor layer; a body contact region formed in the semiconductor layer on the side of the first portion away from the main gate, the body contact region at least in contact with the second portion.
    Type: Application
    Filed: July 21, 2021
    Publication date: May 23, 2024
    Inventor: Le LI
  • Publication number: 20240162737
    Abstract: A power conversion system, an energy storage system and a power supply method are provided. The power conversion system includes a battery management system and an auxiliary power supply. A positive electrode of the auxiliary power supply is connected to a positive electrode of a battery rack. The auxiliary power supply is configured to obtain power from the battery rack, convert the power obtained from the battery rack, and supply the converted power to the battery management system and a load in the power conversion system. The battery management system is configured to sample a voltage of the battery rack and a current of the battery rack, and control charging and discharging of the battery rack based on the voltage and the current.
    Type: Application
    Filed: November 1, 2023
    Publication date: May 16, 2024
    Applicant: Sungrow Power Supply Co., Ltd.
    Inventors: Kai Deng, Le Li, Hao Dong, Feiyang Zheng
  • Publication number: 20240128339
    Abstract: The present disclosure provides a semiconductor device and a manufacturing method therefor. The method includes: providing a semiconductor structure, the semiconductor structure including a semiconductor substrate, a gate disposed on the semiconductor substrate, and an interlayer dielectric layer covering the semiconductor substrate and the gate; wherein the semiconductor structure further includes a first source/drain region and a second source/drain region; defining first connecting holes and at least one first air hole on the first source/drain region and/or the second source/drain region; wherein at least one first air hole is arranged between each adjacent two first connecting holes in an X direction and/or a Y direction, the X direction being a gate length direction, the X direction being perpendicular to the Y direction; sealing each first air hole to define a first cavity in the first air hole; and filling each first connecting hole with a conductive material.
    Type: Application
    Filed: December 22, 2022
    Publication date: April 18, 2024
    Inventors: Guangjie XUE, Le LI, Jun ZHOU
  • Patent number: 11955580
    Abstract: A quantum dot Light Emitting Diode, including an anode, a cathode, and a quantum dot light-emitting layer between the anode and the cathode, a carrier functional layer is arranged between the anode and the cathode. The carrier functional layer contains a magnetic material.
    Type: Grant
    Filed: December 29, 2018
    Date of Patent: April 9, 2024
    Assignee: TCL TECHNOLOGY GROUP CORPORATION
    Inventors: Chaoyu Xiang, Xiongzhi Wang, Le Li, Tao Zhang, Zhenghang Xin, Xue Li
  • Patent number: D1025658
    Type: Grant
    Filed: November 17, 2023
    Date of Patent: May 7, 2024
    Inventor: Le Li