Abstract: The present disclosure provides an acoustic device including a microphone array, a processor, and at least one speaker. The microphone array may be configured to acquire an environmental noise. The processor may be configured to estimate a sound field at a target spatial position using the microphone array. The target spatial position may be closer to an ear canal of a user than each microphone in the microphone array. The processor may be configured to generate a noise reduction signal based on the environmental noise and the sound field estimation of the target spatial position. The at least one speaker may be configured to output a target signal based on the noise reduction signal. The target signal may be used to reduce the environmental noise. The microphone array may be arranged in a target area to minimize an interference signal from the at least one speaker to the microphone array.

Abstract: The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.

Abstract: A cutter head includes: a support platform; a double curved surface member mounted on the support platform and having a first curved surface and a second curved surface; a cutter wheel support member and a roller wheel support member moveably mounted on the support platform, respectively; a cutter wheel and a roller wheel mounted on the cutter wheel support member and the roller wheel support member, respectively; a first transmission mechanism mounted on the support platform, configured to be mated with the first curved surface, and connected to the cutter wheel support member, so as to transmit a movement of the double curved surface member to the cutter wheel; and a second transmission mechanism mounted on the support platform, configured to be mated with the second curved surface, and connected to the roller wheel support member, so as to transmit a movement of the double curved surface member to the roller wheel.

Abstract: A substrate delivery device and a delivery method thereof are described for improving the substrate delivery efficiency, reducing abrasion in substrate delivery, and improving manufacturing efficiency of a display panel. The substrate delivery device comprises a reciprocating aligning mechanism and a screen pickup mechanism. The reciprocating aligning mechanism has a bearing platform carrying the substrate, and a first driving mechanism driving the bearing platform to move so as to bring the carried substrate to a preset position. The screen pickup mechanism has a pickup arm picking up a substrate on the reciprocating aligning mechanism, and a second driving mechanism driving the pickup arm to move. The pickup arm is located in a direction perpendicular to the substrate on the reciprocating aligning mechanism. When the reciprocating aligning mechanism moves to the preset position, the second driving mechanism drives the pickup arm to pick up the substrate on the reciprocating aligning mechanism.

Abstract: A cutter head includes: a support platform; a double curved surface member mounted on the support platform and having a first curved surface and a second curved surface; a cutter wheel support member and a roller wheel support member moveably mounted on the support platform, respectively; a cutter wheel and a roller wheel mounted on the cutter wheel support member and the roller wheel support member, respectively; a first transmission mechanism mounted on the support platform, configured to be mated with the first curved surface, and connected to the cutter wheel support member, so as to transmit a movement of the double curved surface member to the cutter wheel; and a second transmission mechanism mounted on the support platform, configured to be mated with the second curved surface, and connected to the roller wheel support member, so as to transmit a movement of the double curved surface member to the roller wheel.