Patents by Inventor Le Sun

Le Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11968626
    Abstract: Methods, systems, and devices for wireless communications are described. A method for wireless communication at a user equipment (UE) may include: receiving a multicast bandwidth part configuration for multicast communications between a base station and the UE, where the multicast bandwidth part configuration includes a maximum number of multiple-input, multiple-output layers to be used for the multicast communications; establishing a multicast link with the base station for multicast communications; determining to use a reduced number of antennas for multicast reception than the number of antennas used for unicast reception, or determining that the UE is able to decode the multicast communications prior to a remaining portion of the multicast communications; and receiving the multicast communications via the reduced number of antennas, or reducing the radio frequency power prior to completion of a number of repetitions or retransmissions of the multicast communications.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: April 23, 2024
    Assignee: QUALCOMM Incorporated
    Inventors: Xiaoxia Zhang, Jing Sun, Le Liu, Alberto Rico Alvarino, Peter Gaal, Tao Luo
  • Publication number: 20240118205
    Abstract: The invention provides a bacterial cellulose-based biosensor, including bacterial cellulose (BC) and a cell presenting a cellulose-binding module CBM2a on the surface. The cell is attached to BC through CBM2a. The cell expresses CBM2a by using pETDuet-tac as a vector. The pETDuet-tac is obtained by replacing two T7 promoters on the vector pETDuet by tac promoters, that is, an upstream first tac promoter and a downstream second tac promoter. The pETDuet-tac includes a gene encoding a fluorescent protein downstream of the first tac promoter and a gene encoding CBM2a presented on the surface downstream of the second tac promoter. By the BC-based biosensor, efficient and specific immobilization of cells on the BC matrix is enabled, the biological activity of cells is maintained, the fluorescence signal output is enhanced, and sufficient pores are provided for the entry and exit of a detected substance, thereby significantly improving the detection sensitivity.
    Type: Application
    Filed: December 1, 2023
    Publication date: April 11, 2024
    Inventors: Lingfeng LONG, Fubao Sun, Yun Hu, Le Xie
  • Publication number: 20240111836
    Abstract: Data processing is disclosed in various aspects. For instance, an example method includes acquiring a plurality of objects with a sortable schema, the sortable schema specifying at least one field of the plurality of objects; determining metadata, sortable data, and non-sortable data of the plurality of objects on the basis of a value of the at least one field of the plurality of objects; and generating a serialized representation of the plurality of objects on the basis of the metadata, the sortable data, and the non-sortable data. By the method, one group of objects is converted into a serialized representation with sortable information, so that efficient object searching can be achieved without relying on an additional comparator.
    Type: Application
    Filed: December 13, 2022
    Publication date: April 4, 2024
    Inventors: Xia Wang, Xiao Le Shang, Wesley Wei Sun, Young Yangchun Wu, Xiangdong Huang, Xin Li
  • Publication number: 20240111810
    Abstract: Data reads and related data reading processes are described. An example data read method includes: receiving a data read request, the data read request being aimed at target node data stored in a target node of a B+ tree; acquiring node location information, the node location information indicating a storage location of node data in a node data set of the B+ tree, and the node data set including the target node data; and determining a target storage location of the target node data. Beneficially, data stored in the B+ tree can be read and updated efficiently while reducing computing overhead.
    Type: Application
    Filed: December 13, 2022
    Publication date: April 4, 2024
    Inventors: Xiao Le Shang, Xia Wang, Xiangdong Huang, Wesley Wei Sun, Young Yangchun Wu, Xin Li
  • Publication number: 20240091892
    Abstract: The present disclosure discloses a rolling ring shrink fitting tool for rotary equipment, including a lifting frame; a movement slot is formed in a bottom surface of a top of the lifting frame; an output end of a first motor is connected with a main gear; guide rollers are embedded in a lifting seat through bearings; shrink fitting plates are two semicircular structures; lifting lugs are welded on outer sides of the shrink fitting plates; tooth rings are arranged outside the shrink fitting plates; stop rods are fixed on inner walls of the tooth rings; supporting screw rods are embedded at sunken positions on inner walls of the shrink fitting plates through bearings.
    Type: Application
    Filed: November 27, 2023
    Publication date: March 21, 2024
    Inventors: Le LI, Rui YANG, Huaijun JI, Qianbiao XU, Haoji DENG, Yongjie SUN, Hong YANG, Yincheng ZHOU, Bo HU, Jie REN, Lie WANG, Longfei MIAO, Hansi BAI, Tiantian HU, Jinxin ZHAO, Yizhuan QIAN, Changbao CHEN, Xingzheng YANG, Xiaoli GUO, Lihui DU
  • Patent number: 11934788
    Abstract: Embodiments of this disclosure include an encoding method and apparatus. The encoding may include obtaining a target paragraph and a context sentence of the target paragraph, and inputting the target paragraph and the context sentence into a memory encoding model. The encoding may further include obtaining an original vector set and a memory vector set in the input layer and obtaining a first target sentence matrix of the original vector set in the memory layer according to the original vector set and the memory vector set. The encoding may further include obtaining a paragraph vector of the target paragraph in the output layer according to the first target sentence matrix and performing processing based on the paragraph vector.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: March 19, 2024
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Yizhang Tan, Shuo Sun, Jie Cao, Le Tian, Cheng Niu, Jie Zhou
  • Patent number: 11926004
    Abstract: The present disclosure discloses a rolling ring shrink fitting tool for rotary equipment, including a lifting frame; a movement slot is formed in a bottom surface of a top of the lifting frame; an output end of a first motor is connected with a main gear; guide rollers are embedded in a lifting seat through bearings; shrink fitting plates are two semicircular structures; lifting lugs are welded on outer sides of the shrink fitting plates; tooth rings are arranged outside the shrink fitting plates; stop rods are fixed on inner walls of the tooth rings; supporting screw rods are embedded at sunken positions on inner walls of the shrink fitting plates through bearings.
    Type: Grant
    Filed: November 27, 2023
    Date of Patent: March 12, 2024
    Assignee: ZHONGJIAN WUZHOU ENGINEERING EQUIPMENT CO., LTD
    Inventors: Le Li, Rui Yang, Huaijun Ji, Qianbiao Xu, Haoji Deng, Yongjie Sun, Hong Yang, Yincheng Zhou, Bo Hu, Jie Ren, Lie Wang, Longfei Miao, Hansi Bai, Tiantian Hu, Jinxin Zhao, Yizhuan Qian, Changbao Chen, Xingzheng Yang, Xiaoli Guo, Lihui Du
  • Patent number: 11927504
    Abstract: The application proposes a non-destructive testing method for the sealing degree of the small cigarette box packaging, which includes placing the small cigarette box to be tested in an airtight chamber, using a balance cabin to quickly form a stable negative pressure in the airtight chamber; The pressure change of the sealed chamber is continuously measured until equilibrium, and the data model is analyzed and established by using Darcy's law, Fick's diffusion law and the physical process of molecular kinetic theory. Through the non-destructive testing method for the sealing degree of the small cigarette box packaging of the present invention, the traditional destructive measurement (damaged small box packaging) for measuring the sealing degree of cigarette small box is changed into non-destructive testing; The test results have specific physical meaning; The test time of a single sample is reduced to ? of the time of destructive test.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: March 12, 2024
    Assignee: ZHENGZHOU TOBACCO RESEARCH INSTITUTE OF CNTC
    Inventors: Bin Li, Yue Sun, Le Wang, Guangyang Qiu, Mingjian Zhang, Ran Chen, Ke Zhang, Nan Deng
  • Patent number: 11924766
    Abstract: Methods, systems, and devices for wireless communications are described. A method for wireless communication at a user equipment (UE) may include: receiving a multicast bandwidth part configuration for multicast communications between a base station and the UE, where the multicast bandwidth part configuration includes a maximum number of multiple-input, multiple-output layers to be used for the multicast communications; establishing a multicast link with the base station for multicast communications; determining to use a reduced number of antennas for multicast reception than the number of antennas used for unicast reception, or determining that the UE is able to decode the multicast communications prior to a remaining portion of the multicast communications; and receiving the multicast communications via the reduced number of antennas, or reducing the radio frequency power prior to completion of a number of repetitions or retransmissions of the multicast communications.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: March 5, 2024
    Assignee: QUALCOMM Incorporated
    Inventors: Xiaoxia Zhang, Jing Sun, Le Liu, Alberto Rico Alvarino, Peter Gaal, Tao Luo
  • Publication number: 20240071222
    Abstract: A method for controlling a traffic light, a method and apparatus for navigating an unmanned vehicle and a method and apparatus for training a model are provided. An implementation comprises: generating a reinforced traffic light state parameter according to vehicle state representation information of an unmanned vehicle currently contained in a preset area of a target traffic light and a current traffic light state parameter of the target traffic light; and generating a traffic light control action according to the reinforced traffic light state parameter; where the reinforced traffic light state parameter is used to cause an unmanned vehicle navigation end to generate a reinforced vehicle state parameter according to a reinforced traffic light state and a current vehicle state parameter of a target unmanned vehicle, and generate an unmanned vehicle navigation action according to the reinforced vehicle state parameter.
    Type: Application
    Filed: November 7, 2023
    Publication date: February 29, 2024
    Inventors: Qian SUN, Le ZHANG, Jingbo ZHOU, Hui XIONG, Weijia ZHANG, Huan YU, Yu MEI, Weicen LING
  • Publication number: 20240067745
    Abstract: The invention provides an anti-C5 humanized monoclonal antibody with low immunogenicity and low ADCC/CDC function and its application. By modifying the amino acid sequence of the framework region of Eculizumab monoclonal antibody, the immunogenicity was reduced, and the antibody was replaced from IgG2 subtype to IgG1 subtype, and a flexible amino acid sequence was inserted between the CDR3 and CH2 regions of the heavy chain of the IgG1 antibody to reduce the immunogenicity. The purpose of ADCC/CDC function is to improve the stability of the antibody and prolong its half-life. The binding affinity of the monoclonal antibody of the invention to human C5 is similar to that of the original Eculizumab antibody, it can specifically block the complement hemolytic activity of C5 and the production of C5a and can be used for the preparation of C5-targeted paroxysmal nocturnal hemoglobinuria and atypical the drug for the treatment of hemolytic uremic syndrome has excellent clinical therapeutic value.
    Type: Application
    Filed: July 9, 2020
    Publication date: February 29, 2024
    Inventors: Le SUN, Maohua LI, Wenlin REN
  • Publication number: 20240040760
    Abstract: The present invention relates to a circuit board to which a 3D formed electromagnetic shielding film is attached, a 3D formable electromagnetic shielding film, a 3D formed electromagnetic shielding film, and a method for attaching an electromagnetic shielding film to a circuit board. The circuit board includes an electronic component. The 3D formed electromagnetic shielding film includes a molding layer, a shielding layer, and an adhesive film. The molding layer and the adhesive film are laminated. The shielding layer is a conductive non-woven layer embedded in the adhesive film. A ratio of a surface area S2 of the electromagnetic shielding film after forming with an upper surface area of the electronic component deducted to a surface area S1 thereof before forming with the upper surface area of the electronic component deducted is 1.5 to 17.
    Type: Application
    Filed: November 23, 2021
    Publication date: February 1, 2024
    Inventors: Chao Yang, Yuan Zhao, Zhiyong Xu, Ju Le Sun
  • Patent number: 11884566
    Abstract: Metal bioremediation and metal mining strategies can include compositions and methods.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: January 30, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: George Le-Le Sun, Angela M. Belcher
  • Patent number: 11835749
    Abstract: A backlight and a display device are provided herein, which is related to the field of display technology and intends to improve visual effect of the image displayed by the display device. The backlight may include a back plate, a light guide plate and a light source. The back plate includes an accommodation groove, and the light guide plate includes a holding groove at a first side surface of the light guide plate. The light source includes at least one light emitting element. The holding groove is configured to hold at least a portion of the at least one light emitting element, and the accommodation groove is configured to accommodate the light guide plate and the light source.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: December 5, 2023
    Assignees: Ordos Yuansheng Optoelectronics Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Ruijun Hao, Long Lian, Tianlei Shi, Wulijibaier Tang, Yuefeng Li, Zhongping Zhao, Xiaojie Wang, Wei Ning, Feixiang Guo, Xuefeng Zhang, Haifang Hu, Yongkai Wu, Le Sun
  • Publication number: 20230257472
    Abstract: The present invention relates to an anti-CD70 antibody and an application thereof. Specifically, the present disclosure relates to an anti-CD70 antibody, which comprises a light chain variable region and a heavy chain variable region of the antibody, and a use as a drug.
    Type: Application
    Filed: June 29, 2021
    Publication date: August 17, 2023
    Inventors: Le SUN, Xin YE, Yuxiao CHEN, Xinsheng JIN, Weikang TAO
  • Publication number: 20230242634
    Abstract: Provided is an anti-TNF-? humanized monoclonal antibody, TCX060, wherein the antibody is obtained by means of modifying Certolizumab as follows: (1) removing PEG modification; (2) transforming same into a full-length antibody of a human IgG1 subtype; and (3) inserting a flexible amino acid fragment between CDR3 and CH2 regions.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 3, 2023
    Inventors: Le SUN, Wenlin REN
  • Patent number: 11497799
    Abstract: The present invention relates to the discovery that inhibition of Dickkopf2 (DKK2) increases CD8+ cytotoxic T lymphocyte (CTL) activity, attenuates tumor angiogenesis, and hence suppresses tumor formation. Thus, in various embodiments described herein, the methods of the invention relate to methods of treating cancer by administering to a patient an effective amount of DKK2 gene depleting agent, methods for providing anti-tumor immunity and anti-tumor angiogenesis in a subject, methods of stimulating a T cell mediated immune response to a cell population or a tissue and suppressing tumor angiogenesis in a subject. Additionally, the current invention includes methods of diagnosing a cancer or a predisposition of developing a cancer or a metastasis and methods for determining the use of immunotherapy treatment or cancer vaccine for treating cancer. Furthermore, the invention encompasses a pharmaceutical composition for treating cancer as well as a kit for carrying out the aforementioned methods.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: November 15, 2022
    Assignee: YALE UNIVERSITY
    Inventors: Dianqing Wu, Le Sun
  • Publication number: 20220342139
    Abstract: A backlight and a display device are provided herein, which is related to the field of display technology and intends to improve visual effect of the image displayed by the display device. The backlight may include a back plate, a light guide plate and a light source. The back plate includes an accommodation groove, and the light guide plate includes a holding groove at a first side surface of the light guide plate. The light source includes at least one light emitting element. The holding groove is configured to hold at least a portion of the at least one light emitting element, and the accommodation groove is configured to accommodate the light guide plate and the light source.
    Type: Application
    Filed: January 8, 2021
    Publication date: October 27, 2022
    Inventors: Ruijun HAO, Long LIAN, Tianlei SHI, Wulijibaier TANG, Yuefeng LI, Zhongping ZHAO, Xiaojie WANG, Wei NING, Feixiang GUO, Xuefeng ZHANG, Haifang HU, Yongkai WU, Le SUN
  • Publication number: 20220275100
    Abstract: The present application provides an anti-CD38 antibody, an antigen-binding fragment thereof, and pharmaceutical use. Specifically, the present application provides a murine-derived antibody, a chimeric antibody or a humanized antibody comprising a CDR region of the anti-CD38 antibdoy, a pharmaceutical composition comprising the anti-CD38 antibody or the antigen-binding fragment thereof, and an application thereof as a drug. In particular, the present application provides an application of a humanized anti-CD38 antibody in preparing a drug for treating a CD38 positive disease or disorder.
    Type: Application
    Filed: September 10, 2019
    Publication date: September 1, 2022
    Inventors: Xin Ye, Le Sun, Mingjuan Song, Beibei Fu, Xiaohua Wang, Lei Zhang, Weikang Tao
  • Publication number: 20220275068
    Abstract: The present invention relates to the discovery that inhibition of Dickkopf2 (DKK2) increases CD8+ cytotoxic T lymphocyte (CTL) activity, attenuates tumor, and hence suppresses tumor formation. Thus, in various embodiments described herein, the methods of the invention relate to methods of treating cancer by administering to a patient an effective amount of a humanized anti-DKK2 antibody, methods for providing anti-tumor immunity in a subject, methods of stimulating a T cell mediated immune response to a cell population or a tissue and suppressing tumor in a subject. Additionally, the current invention includes methods of diagnosing a cancer or a predisposition of developing a cancer or a metastasis and methods for determining the use of immunotherapy treatment or cancer vaccine for treating cancer. Furthermore, the invention encompasses a pharmaceutical composition for treating cancer as well as a kit for carrying out the aforementioned methods.
    Type: Application
    Filed: July 10, 2019
    Publication date: September 1, 2022
    Inventor: Le SUN