Patents by Inventor Leah R. Hanson

Leah R. Hanson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intranasal delivery of AAV encoding therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
    Patent number: 9249424
    Abstract: The invention provides a method to prevent, inhibit or treat one or more neurological symptoms associated with a lysosomal storage disease in a mammal in need thereof, which includes intranasally administering to the mammal a composition comprising an effective amount of a lysosomal storage enzyme or a recombinant adeno-associated virus vector comprising an open reading frame encoding a lysosomal storage enzyme. Also provided are compositions and devices useful in the methods.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: February 2, 2016
    Assignees: Regents of the University of Minnesota, HealthPartners Research & Education
    Inventors: Daniel A. Wolf, William H. Frey, II, R. Scott McIvor, Leah R. Hanson
  • INTRANASAL DELIVERY OF AAV ENCODING THERAPEUTIC ENZYMES TO THE CENTRAL NERVOUS SYSTEM FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES
    Publication number: 20140171491
    Abstract: The invention provides a method to prevent, inhibit or treat one or more neurological symptoms associated with a lysosomal storage disease in a mammal in need thereof, which includes intranasally administering to the mammal a composition comprising an effective amount of a lysosomal storage enzyme or a recombinant adeno-associated virus vector comprising an open reading frame encoding a lysosomal storage enzyme. Also provided are compositions and devices useful in the methods.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 19, 2014
    Applicants: HealthPartners Research & Education, Regents of the University of Minnesota
    Inventors: Daniel A. Wolf, William H. Frey, II, R. Scott McIvor, Leah R. Hanson
  • Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
    Patent number: 8609088
    Abstract: The invention provides a method to prevent, inhibit or treat one or more neurological symptoms associated with a lysosomal storage disease in a mammal in need thereof, which includes intranasally administering to the mammal a composition comprising an effective amount of a lysosomal storage enzyme or a recombinant adeno-associated virus vector comprising an open reading frame encoding a lysosomal storage enzyme. Also provided are compositions and devices useful in the methods.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: December 17, 2013
    Assignees: Regents of the University of Minnesota, HealthPartners Research & Education
    Inventors: Daniel A. Wolf, William H. Frey, II, R. Scott McIvor, Leah R. Hanson
  • INTRANASAL DELIVERY OF THERAPEUTIC ENZYMES TO THE CENTRAL NERVOUS SYSTEM FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES
    Publication number: 20120288489
    Abstract: The invention provides a method to prevent, inhibit or treat one or more neurological symptoms associated with a lysosomal storage disease in a mammal in need thereof, which includes intranasally administering to the mammal a composition comprising an effective amount of a lysosomal storage enzyme or a recombinant adeno-associated virus vector comprising an open reading frame encoding a lysosomal storage enzyme. Also provided are compositions and devices useful in the methods.
    Type: Application
    Filed: May 7, 2012
    Publication date: November 15, 2012
    Applicants: Health Partners Research Foundation, Regents of the University of Minnesota
    Inventors: Daniel A. Wolf, William H. Frey, II, R. Scott Mclvor, Leah R. Hanson