Patents by Inventor Leah R. Soffer
Leah R. Soffer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11554042Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: GrantFiled: November 8, 2018Date of Patent: January 17, 2023Assignee: Gyroscope Therapeutics LimitedInventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Publication number: 20210298951Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: ApplicationFiled: June 14, 2021Publication date: September 30, 2021Inventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Patent number: 11058576Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: GrantFiled: November 8, 2018Date of Patent: July 13, 2021Assignee: GYROSCOPE THERAPEUTICS LIMITEDInventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Patent number: 10322028Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, an actuation assembly, and a detection/visualization system. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis. The cannula may be inserted through a sclerotomy incision and advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer. The detection/visualization system is operable to detect or visualize penetration of the choroid of a patient's eye and provide feedback to the operator and/or automatic control of the apparatus based on penetration of the choroid.Type: GrantFiled: September 1, 2015Date of Patent: June 18, 2019Assignee: ORBIT BIOMEDICAL LIMITEDInventors: Daniel W. Price, Brendan J. Oberkircher, Saeed Sokhanvar, Daniel J. Yasevac, Michel Bruehwiler, Leah R. Soffer, Gregory W. Johnson, William D. Dannaher, Stefan Troller, Urban Schnell, Jean Christophe Roulet, Alain Saurer, Michael F. Keane
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Publication number: 20190142635Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: ApplicationFiled: November 8, 2018Publication date: May 16, 2019Inventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Publication number: 20190142634Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: ApplicationFiled: November 8, 2018Publication date: May 16, 2019Inventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Patent number: 10226379Abstract: An apparatus for delivering therapeutic agent to an eye includes a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: GrantFiled: February 11, 2015Date of Patent: March 12, 2019Assignee: ORBIT BIOMEDICAL LIMITEDInventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Patent number: 10064752Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an automated actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: GrantFiled: August 31, 2015Date of Patent: September 4, 2018Assignee: ORBIT BIOMEDICAL LIMITEDInventors: Daniel W. Price, Isaac J. Khan, Brendan J. Oberkircher, Saeed Sokhanvar, Daniel J. Yasevac, Michel Bruehwiler, Leah R. Soffer, Mohammadreza Ramerzanifard, Mary Carter
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Publication number: 20160074217Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an automated actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: ApplicationFiled: August 31, 2015Publication date: March 17, 2016Inventors: Daniel W. Price, Isaac J. Khan, Brendan J. Oberkircher, Saeed Sokhanvar, Daniel J. Yasevac, Michel Bruehwiler, Leah R. Soffer, Reza Fard, Mary Carter
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Publication number: 20160074212Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, an actuation assembly, and a detection/visualization system. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis. The cannula may be inserted through a sclerotomy incision and advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer. The detection/visualization system is operable to detect or visualize penetration of the choroid of a patient's eye and provide feedback to the operator and/or automatic control of the apparatus based on penetration of the choroid.Type: ApplicationFiled: September 1, 2015Publication date: March 17, 2016Inventors: Daniel W. Price, Brendan J. Oberkircher, Saeed Sokhanvar, Daniel J. Yasevac, Michel Bruehwiler, Leah R. Soffer, Gregory W. Johnson, William D. Dannaher, Stefan Troller, Urban Schnell, Jean Christophe Roulet, Alain Saurer, Michael F. Keane
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Publication number: 20150223977Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.Type: ApplicationFiled: February 11, 2015Publication date: August 13, 2015Inventors: Brendan J. Oberkircher, Daniel W. Price, Michael F. Keane, Saeed Sokhanvar, Daniel J. Yasevac, Michel G. Bruehwiler, Leah R. Soffer, Isaac J. Khan, Benjamin L. Ko, Christopher D. Riemann, Nathan D. Grubbs
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Patent number: 6987257Abstract: An attitude determination system and method is provided that includes at least two sensor sets. Each sensor set is configured to detect electromagnetic radiation, such as light of a known frequency. Specifically, each sensor set is configured to detect electromagnetic radiation from a one of a plurality of point sources, where each of the plurality of point sources emits electromagnetic radiation of a different frequency. Each sensor set includes at least three sensors, with each of the three sensors having a different orientation. The three sensors in the sensor set are used to determine a relative orientation of the vehicle with respect to one of the point sources. The at least two sensor sets in the system determine the relative orientation with respect to at least two point sources. By placing the sensors on a vehicle and knowing the direction to the point sources in a reference frame coordinate system, the orientation of the vehicle with respect to this reference frame can be estimated.Type: GrantFiled: January 28, 2003Date of Patent: January 17, 2006Assignee: Honeywell International Inc.Inventors: Mason A. Peck, Leah R. Soffer
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Publication number: 20040144910Abstract: An attitude determination system and method is provided that includes at least two sensor sets. Each sensor set is configured to detect electromagnetic radiation, such as light of a known frequency. Specifically, each sensor set is configured to detect electromagnetic radiation from a one of a plurality of point sources, where each of the plurality of point sources emits electromagnetic radiation of a different frequency. Each sensor set includes at least three sensors, with each of the three sensors having a different orientation. The three sensors in the sensor set are used to determine a relative orientation of the vehicle with respect to one of the point sources. The at least two sensor sets in the system determine the relative orientation with respect to at least two point sources. By placing the sensors on a vehicle and knowing the direction to the point sources in a reference frame coordinate system, the orientation of the vehicle with respect to this reference frame can be estimated.Type: ApplicationFiled: January 28, 2003Publication date: July 29, 2004Inventors: Mason A. Peck, Leah R. Soffer