Patents by Inventor Leander GAECHTER

Leander GAECHTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11808932
    Abstract: A module for a microscope stand comprises a control device with at least one computer hardware component being configured to control the microscope stand. The module further comprises a locating device configured to interact with another locating device formed in a housing of the microscope stand for mounting the module at a predetermined installation site within the housing.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: November 7, 2023
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventors: Patrick Szabo, Leander Gaechter
  • Patent number: 11311886
    Abstract: The invention relates to a holding apparatus (100) for sample carriers (200) for use in cryomicroscopy, encompassing: a body having at least one sample carrier receptacle that comprises at least one sample carrier support surface against which at least one sample carrier (200) is abuttable; at least one first sample carrier holding means (121); and at least one second sample carrier holding means (131) that is configured to impinge upon the sample carrier (200) with force against the first sample carrier holding means (121); and to an arrangement having a manipulation container and such a holding apparatus (100), and to methods for introducing and withdrawing a sample carrier (200).
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: April 26, 2022
    Assignee: LEICA MIKROSYSTEME GMBH
    Inventors: Reinhard Lihl, Leander Gaechter, Saskia Mimietz-Oeckler
  • Publication number: 20210263296
    Abstract: A module (104) for a microscope stand (100) comprises a control device (118) with at least one computer hardware component (120, 122) being configured to control the microscope stand (100). The module (104) further comprises a locating device (164) configured to interact with another locating device (162) formed in a housing (102) of the microscope stand (100) for mounting the module (104) at a predetermined installation site within the housing (102).
    Type: Application
    Filed: February 22, 2021
    Publication date: August 26, 2021
    Inventors: Patrick SZABO, Leander GAECHTER
  • Patent number: 10901196
    Abstract: In a light microscope (1) for cryomicroscopy, encompassing at least an objective (2) and a sample stage (3) having a cutout (7) for a coolable holder (8) for a sample carrier mount, the cutout (7) being covered by a cover (6), the sample stage (3) is displaceable in two horizontal directions (4). The cover (6) rests floatingly on the sample stage (3), and the objective (2) passes through a cutout (12), corresponding to the objective (2), in the cover (6). The method for cooling a holder (8) for a sample carrier mount in a light microscope (1) for cryomicroscopes, by means of a flow of liquid nitrogen through a cooling conduit (15), open at at least one end, in the holder (8), is notable for the fact that the quantity of liquid nitrogen is dimensioned so that all of the nitrogen is present in gaseous form at at least one open end (16) of the cooling conduit (15).
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: January 26, 2021
    Assignees: LEICA MIKROSYSTEME GMBH, EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Reinhard Lihl, John Briggs, Martin Schorb, Leander Gaechter
  • Patent number: 10551285
    Abstract: The invention relates to a sample transfer device (10) for reception of a sample, having a transfer rod (4) that is configured for reception of a sample holder, the sample holder to be arranged in a chamber (1) of the sample transfer device (10) for the purpose of transferring the sample to a processing unit or analytical unit (200), at least one measurement device (3, 8) for measuring a physical variable being arranged inside the sample transfer device (10).
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: February 4, 2020
    Assignee: Leica Mikrosysteme GmbH
    Inventors: Leander Gaechter, Günther Bock, Thomas Pfeifer
  • Patent number: 10217603
    Abstract: A loading station (100, 200) for translocating a frozen sample for electron microscopy, encompassing a chamber (104, 204), open toward the top, that is fillable at least partly with a coolant, the chamber (104, 204) comprising in its side wall at least two ports (101a, 102a, 103a) each for different sample transfer devices (101, 102, 103), the ports (101a, 102a, 103a) permitting introduction of a frozen sample into the chamber (104, 204) via a selected sample transfer device and withdrawal of a frozen sample from the chamber via a respective different sample transfer device; and wherein a receptacle (108, 208) for at least two differently configured sample holders (109, 110) is arranged in the chamber (104, 204), the at least two sample holders (109, 110) being detachably fastenable to at least one of the sample transfer devices (101) for introduction of the frozen sample into the chamber (104, 204) and for withdrawal of the frozen sample from the chamber (104, 204).
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: February 26, 2019
    Assignee: Leica Mikrosysteme GmbH
    Inventors: Reinhard Lihl, Leander Gaechter
  • Patent number: 10144010
    Abstract: In a manipulation container (1) for cryomicroscopy, having at least one holder (9) for a sample carrier mount (7) and at least one manipulation opening (2) for manipulating sample carriers or sample carrier mounts (7), the holder (9) for a sample carrier mount (7) is movable into a displacement path (11), passing completely through the manipulation container (1), of a displacement apparatus (3) for the sample carrier mount (7).
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: December 4, 2018
    Assignees: Leica Mikrosysteme GmbH, European Molecular Biology Laboratory
    Inventors: Reinhard Lihl, Leander Gaechter, John Briggs, Martin Schorb
  • Publication number: 20180290144
    Abstract: The invention relates to a holding apparatus (100) for sample carriers (200) for use in cryomicroscopy, encompassing: a body having at least one sample carrier receptacle that comprises at least one sample carrier support surface against which at least one sample carrier (200) is abuttable; at least one first sample carrier holding means (121); and at least one second sample carrier holding means (131) that is configured to impinge upon the sample carrier (200) with force against the first sample carrier holding means (121); and to an arrangement having a manipulation container and such a holding apparatus (100), and to methods for introducing and withdrawing a sample carrier (200).
    Type: Application
    Filed: April 3, 2018
    Publication date: October 11, 2018
    Inventors: Reinhard LIHL, Leander GAECHTER, Saskia MIMIETZ-OECKLER
  • Publication number: 20170370814
    Abstract: The invention relates to a sample transfer device (10) for reception of a sample, having a transfer rod (4) that is configured for reception of a sample holder, the sample holder to be arranged in a chamber (1) of the sample transfer device (10) for the purpose of transferring the sample to a processing unit or analytical unit (200), at least one measurement device (3, 8) for measuring a physical variable being arranged inside the sample transfer device (10).
    Type: Application
    Filed: January 14, 2016
    Publication date: December 28, 2017
    Inventors: Leander GAECHTER, Günther BOCK, Thomas PFEIFER
  • Publication number: 20170227752
    Abstract: In a light microscope (1) for cryomicroscopy, encompassing at least an objective (2) and a sample stage (3) having a cutout (7) for a coolable holder (8) for a sample carrier mount, the cutout (7) being covered by a cover (6), the sample stage (3) is displaceable in two horizontal directions (4). The cover (6) rests floatingly on the sample stage (3), and the objective (2) passes through a cutout (12), corresponding to the objective (2), in the cover (6). The method for cooling a holder (8) for a sample carrier mount in a light microscope (1) for cryomicroscopes, by means of a flow of liquid nitrogen through a cooling conduit (15), open at at least one end, in the holder (8), is notable for the fact that the quantity of liquid nitrogen is dimensioned so that all of the nitrogen is present in gaseous form at at least one open end (16) of the cooling conduit (15).
    Type: Application
    Filed: July 15, 2015
    Publication date: August 10, 2017
    Applicants: Leica Mikrosysteme GmbH, European Molecular Biology Laboratory
    Inventors: Reinhard LIHL, John BRIGGS, Martin SCHORB, Leander GAECHTER
  • Publication number: 20170213694
    Abstract: A loading station (100, 200) for translocating a frozen sample for electron microscopy, encompassing a chamber (104, 204), open toward the top, that is fillable at least partly with a coolant, the chamber (104, 204) comprising in its side wall at least two ports (101a, 102a, 103a) each for different sample transfer devices (101, 102, 103), the ports (101a, 102a, 103a) permitting introduction of a frozen sample into the chamber (104, 204) via a selected sample transfer device and withdrawal of a frozen sample from the chamber via a respective different sample transfer device; and wherein a receptacle (108, 208) for at least two differently configured sample holders (109, 110) is arranged in the chamber (104, 204), the at least two sample holders (109, 110) being detachably fastenable to at least one of the sample transfer devices (101) for introduction of the frozen sample into the chamber (104, 204) and for withdrawal of the frozen sample from the chamber (104, 204).
    Type: Application
    Filed: July 15, 2015
    Publication date: July 27, 2017
    Inventors: Reinhard LIHL, Leander GAECHTER
  • Publication number: 20160030941
    Abstract: In a manipulation container (1) for cryomicroscopy, having at least one holder (9) for a sample carrier mount (7) and at least one manipulation opening (2) for manipulating sample carriers or sample carrier mounts (7), the holder (9) for a sample carrier mount (7) is movable into a displacement path (11), passing completely through the manipulation container (1), of a displacement apparatus (3) for the sample carrier mount (7).
    Type: Application
    Filed: July 21, 2015
    Publication date: February 4, 2016
    Inventors: Reinhard LIHL, Leander GAECHTER, John BRIGGS, Martin SCHORB
  • Patent number: 8395130
    Abstract: A mount (100, 200) for holding an electron microscopy sample carrier (310) comprises a base plate (101) having an opening (103) through a middle region thereof and a support surface (107) for the sample carrier (310) extending at least partly around the opening (103), a holding apparatus (104a, 104b) for frictionally engaged holding of the sample carrier (310) on the support surface (107) being provided on the base plate (101), the holding apparatus (104a, 104b) comprising at least two mutually independent clip elements (104a, 104b) that extend from the base plate (101) toward the opening (103) and by means of which edge regions (313a, 313b), spaced apart from one another, of the electron microscopy sample carrier (310) are holdable on the support surface (107). The invention further encompasses a loading apparatus for loading a mount with an electron microscopy sample carrier, and a method for using the loading apparatus.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: March 12, 2013
    Assignee: Leica Microsystems (Schweiz) AG
    Inventor: Leander Gächter
  • Publication number: 20120132828
    Abstract: A mount (100, 200) for holding an electron microscopy sample carrier (310) comprises a base plate (101) having an opening (103) through a middle region thereof and a support surface (107) for the sample carrier (310) extending at least partly around the opening (103), a holding apparatus (104a, 104b) for frictionally engaged holding of the sample carrier (310) on the support surface (107) being provided on the base plate (101), the holding apparatus (104a, 104b) comprising at least two mutually independent clip elements (104a, 104b) that extend from the base plate (101) toward the opening (103) and by means of which edge regions (313a, 313b), spaced apart from one another, of the electron microscopy sample carrier (310) are holdable on the support surface (107). The invention further encompasses a loading apparatus for loading a mount with an electron microscopy sample carrier, and a method for using the loading apparatus.
    Type: Application
    Filed: November 28, 2011
    Publication date: May 31, 2012
    Applicant: Leica Microsystems (Schweiz) AG
    Inventor: Leander GÄCHTER