Patents by Inventor Leander GAECHTER
Leander GAECHTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11808932Abstract: A module for a microscope stand comprises a control device with at least one computer hardware component being configured to control the microscope stand. The module further comprises a locating device configured to interact with another locating device formed in a housing of the microscope stand for mounting the module at a predetermined installation site within the housing.Type: GrantFiled: February 22, 2021Date of Patent: November 7, 2023Assignee: Leica Instruments (Singapore) Pte. Ltd.Inventors: Patrick Szabo, Leander Gaechter
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Patent number: 11311886Abstract: The invention relates to a holding apparatus (100) for sample carriers (200) for use in cryomicroscopy, encompassing: a body having at least one sample carrier receptacle that comprises at least one sample carrier support surface against which at least one sample carrier (200) is abuttable; at least one first sample carrier holding means (121); and at least one second sample carrier holding means (131) that is configured to impinge upon the sample carrier (200) with force against the first sample carrier holding means (121); and to an arrangement having a manipulation container and such a holding apparatus (100), and to methods for introducing and withdrawing a sample carrier (200).Type: GrantFiled: April 3, 2018Date of Patent: April 26, 2022Assignee: LEICA MIKROSYSTEME GMBHInventors: Reinhard Lihl, Leander Gaechter, Saskia Mimietz-Oeckler
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Publication number: 20210263296Abstract: A module (104) for a microscope stand (100) comprises a control device (118) with at least one computer hardware component (120, 122) being configured to control the microscope stand (100). The module (104) further comprises a locating device (164) configured to interact with another locating device (162) formed in a housing (102) of the microscope stand (100) for mounting the module (104) at a predetermined installation site within the housing (102).Type: ApplicationFiled: February 22, 2021Publication date: August 26, 2021Inventors: Patrick SZABO, Leander GAECHTER
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Patent number: 10901196Abstract: In a light microscope (1) for cryomicroscopy, encompassing at least an objective (2) and a sample stage (3) having a cutout (7) for a coolable holder (8) for a sample carrier mount, the cutout (7) being covered by a cover (6), the sample stage (3) is displaceable in two horizontal directions (4). The cover (6) rests floatingly on the sample stage (3), and the objective (2) passes through a cutout (12), corresponding to the objective (2), in the cover (6). The method for cooling a holder (8) for a sample carrier mount in a light microscope (1) for cryomicroscopes, by means of a flow of liquid nitrogen through a cooling conduit (15), open at at least one end, in the holder (8), is notable for the fact that the quantity of liquid nitrogen is dimensioned so that all of the nitrogen is present in gaseous form at at least one open end (16) of the cooling conduit (15).Type: GrantFiled: July 15, 2015Date of Patent: January 26, 2021Assignees: LEICA MIKROSYSTEME GMBH, EUROPEAN MOLECULAR BIOLOGY LABORATORYInventors: Reinhard Lihl, John Briggs, Martin Schorb, Leander Gaechter
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Patent number: 10551285Abstract: The invention relates to a sample transfer device (10) for reception of a sample, having a transfer rod (4) that is configured for reception of a sample holder, the sample holder to be arranged in a chamber (1) of the sample transfer device (10) for the purpose of transferring the sample to a processing unit or analytical unit (200), at least one measurement device (3, 8) for measuring a physical variable being arranged inside the sample transfer device (10).Type: GrantFiled: January 14, 2016Date of Patent: February 4, 2020Assignee: Leica Mikrosysteme GmbHInventors: Leander Gaechter, Günther Bock, Thomas Pfeifer
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Patent number: 10217603Abstract: A loading station (100, 200) for translocating a frozen sample for electron microscopy, encompassing a chamber (104, 204), open toward the top, that is fillable at least partly with a coolant, the chamber (104, 204) comprising in its side wall at least two ports (101a, 102a, 103a) each for different sample transfer devices (101, 102, 103), the ports (101a, 102a, 103a) permitting introduction of a frozen sample into the chamber (104, 204) via a selected sample transfer device and withdrawal of a frozen sample from the chamber via a respective different sample transfer device; and wherein a receptacle (108, 208) for at least two differently configured sample holders (109, 110) is arranged in the chamber (104, 204), the at least two sample holders (109, 110) being detachably fastenable to at least one of the sample transfer devices (101) for introduction of the frozen sample into the chamber (104, 204) and for withdrawal of the frozen sample from the chamber (104, 204).Type: GrantFiled: July 15, 2015Date of Patent: February 26, 2019Assignee: Leica Mikrosysteme GmbHInventors: Reinhard Lihl, Leander Gaechter
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Patent number: 10144010Abstract: In a manipulation container (1) for cryomicroscopy, having at least one holder (9) for a sample carrier mount (7) and at least one manipulation opening (2) for manipulating sample carriers or sample carrier mounts (7), the holder (9) for a sample carrier mount (7) is movable into a displacement path (11), passing completely through the manipulation container (1), of a displacement apparatus (3) for the sample carrier mount (7).Type: GrantFiled: July 21, 2015Date of Patent: December 4, 2018Assignees: Leica Mikrosysteme GmbH, European Molecular Biology LaboratoryInventors: Reinhard Lihl, Leander Gaechter, John Briggs, Martin Schorb
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Publication number: 20180290144Abstract: The invention relates to a holding apparatus (100) for sample carriers (200) for use in cryomicroscopy, encompassing: a body having at least one sample carrier receptacle that comprises at least one sample carrier support surface against which at least one sample carrier (200) is abuttable; at least one first sample carrier holding means (121); and at least one second sample carrier holding means (131) that is configured to impinge upon the sample carrier (200) with force against the first sample carrier holding means (121); and to an arrangement having a manipulation container and such a holding apparatus (100), and to methods for introducing and withdrawing a sample carrier (200).Type: ApplicationFiled: April 3, 2018Publication date: October 11, 2018Inventors: Reinhard LIHL, Leander GAECHTER, Saskia MIMIETZ-OECKLER
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Publication number: 20170370814Abstract: The invention relates to a sample transfer device (10) for reception of a sample, having a transfer rod (4) that is configured for reception of a sample holder, the sample holder to be arranged in a chamber (1) of the sample transfer device (10) for the purpose of transferring the sample to a processing unit or analytical unit (200), at least one measurement device (3, 8) for measuring a physical variable being arranged inside the sample transfer device (10).Type: ApplicationFiled: January 14, 2016Publication date: December 28, 2017Inventors: Leander GAECHTER, Günther BOCK, Thomas PFEIFER
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Publication number: 20170227752Abstract: In a light microscope (1) for cryomicroscopy, encompassing at least an objective (2) and a sample stage (3) having a cutout (7) for a coolable holder (8) for a sample carrier mount, the cutout (7) being covered by a cover (6), the sample stage (3) is displaceable in two horizontal directions (4). The cover (6) rests floatingly on the sample stage (3), and the objective (2) passes through a cutout (12), corresponding to the objective (2), in the cover (6). The method for cooling a holder (8) for a sample carrier mount in a light microscope (1) for cryomicroscopes, by means of a flow of liquid nitrogen through a cooling conduit (15), open at at least one end, in the holder (8), is notable for the fact that the quantity of liquid nitrogen is dimensioned so that all of the nitrogen is present in gaseous form at at least one open end (16) of the cooling conduit (15).Type: ApplicationFiled: July 15, 2015Publication date: August 10, 2017Applicants: Leica Mikrosysteme GmbH, European Molecular Biology LaboratoryInventors: Reinhard LIHL, John BRIGGS, Martin SCHORB, Leander GAECHTER
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Publication number: 20170213694Abstract: A loading station (100, 200) for translocating a frozen sample for electron microscopy, encompassing a chamber (104, 204), open toward the top, that is fillable at least partly with a coolant, the chamber (104, 204) comprising in its side wall at least two ports (101a, 102a, 103a) each for different sample transfer devices (101, 102, 103), the ports (101a, 102a, 103a) permitting introduction of a frozen sample into the chamber (104, 204) via a selected sample transfer device and withdrawal of a frozen sample from the chamber via a respective different sample transfer device; and wherein a receptacle (108, 208) for at least two differently configured sample holders (109, 110) is arranged in the chamber (104, 204), the at least two sample holders (109, 110) being detachably fastenable to at least one of the sample transfer devices (101) for introduction of the frozen sample into the chamber (104, 204) and for withdrawal of the frozen sample from the chamber (104, 204).Type: ApplicationFiled: July 15, 2015Publication date: July 27, 2017Inventors: Reinhard LIHL, Leander GAECHTER
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Publication number: 20160030941Abstract: In a manipulation container (1) for cryomicroscopy, having at least one holder (9) for a sample carrier mount (7) and at least one manipulation opening (2) for manipulating sample carriers or sample carrier mounts (7), the holder (9) for a sample carrier mount (7) is movable into a displacement path (11), passing completely through the manipulation container (1), of a displacement apparatus (3) for the sample carrier mount (7).Type: ApplicationFiled: July 21, 2015Publication date: February 4, 2016Inventors: Reinhard LIHL, Leander GAECHTER, John BRIGGS, Martin SCHORB
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Patent number: 8395130Abstract: A mount (100, 200) for holding an electron microscopy sample carrier (310) comprises a base plate (101) having an opening (103) through a middle region thereof and a support surface (107) for the sample carrier (310) extending at least partly around the opening (103), a holding apparatus (104a, 104b) for frictionally engaged holding of the sample carrier (310) on the support surface (107) being provided on the base plate (101), the holding apparatus (104a, 104b) comprising at least two mutually independent clip elements (104a, 104b) that extend from the base plate (101) toward the opening (103) and by means of which edge regions (313a, 313b), spaced apart from one another, of the electron microscopy sample carrier (310) are holdable on the support surface (107). The invention further encompasses a loading apparatus for loading a mount with an electron microscopy sample carrier, and a method for using the loading apparatus.Type: GrantFiled: November 28, 2011Date of Patent: March 12, 2013Assignee: Leica Microsystems (Schweiz) AGInventor: Leander Gächter
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Publication number: 20120132828Abstract: A mount (100, 200) for holding an electron microscopy sample carrier (310) comprises a base plate (101) having an opening (103) through a middle region thereof and a support surface (107) for the sample carrier (310) extending at least partly around the opening (103), a holding apparatus (104a, 104b) for frictionally engaged holding of the sample carrier (310) on the support surface (107) being provided on the base plate (101), the holding apparatus (104a, 104b) comprising at least two mutually independent clip elements (104a, 104b) that extend from the base plate (101) toward the opening (103) and by means of which edge regions (313a, 313b), spaced apart from one another, of the electron microscopy sample carrier (310) are holdable on the support surface (107). The invention further encompasses a loading apparatus for loading a mount with an electron microscopy sample carrier, and a method for using the loading apparatus.Type: ApplicationFiled: November 28, 2011Publication date: May 31, 2012Applicant: Leica Microsystems (Schweiz) AGInventor: Leander GÄCHTER