Patents by Inventor Leander Moebius

Leander Moebius has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of erythio-.alpha.piperid-2-yl-2,8-bis-trifluoro-methyl)-quinolin-4-yl-meth anol
    Patent number: 4327215
    Abstract: The present invention relates to a simplified process, which avoids organo-lithium intermediates, for the preparation of erythro-.alpha.-piperid-2-yl-2,8-bis-(trifluoromethyl)-quinolin-4-yl-metha nol, wherein 2,8-bis-(trifluoromethyl)-quinoline-4-carboxylic acid or a salt thereof is reacted with a pyrid-2-yl-magnesium halide to give pyrid-2-yl-2,8-bis-(trifluoromethyl)-quinolin-4-yl ketone in the manner of a Grignard reaction, and this product is hydrogenated, in a conventional manner, to give erythro-.alpha.-piperid-2-yl-2,8-bis-(trifluoromethyl)-quinolin-4-yl-metha nol.
    Type: Grant
    Filed: October 3, 1980
    Date of Patent: April 27, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Eckhard Hickmann, Heinz-Guenter Oeser, Leander Moebius