Abstract: The present invention relates to a biomaterial for use as medicament intended for the treatment of cardiac tissues, to a process for producing the biomaterial, and also to a biomaterial according to the invention for use as medicament or medical device. The biomaterial of the present invention comprises a biocompatible biodegradable polymer including extracellular vesicles from stem cells. The process of the present invention comprises a step of soaking the biocompatible biodegradable polymer in a biocompatible liquid medium comprising extracellular vesicles from stem cells or from the differentiated derivatives thereof, or a mixing of the biocompatible biodegradable polymer or of the corresponding monomer(s) with extracellular vesicles from stem cells. The biomaterial according to the invention is of use as medicament, especially for the treatment of deficient human or animal cardiac tissue.