Patents by Inventor Lech Kozerski

Lech Kozerski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-Ethyl-10-hydroxycamptothecin derivatives for use in the treatment of cancer
    Publication number: 20220081448
    Abstract: The subject of the present invention are water-soluble derivatives of camptothecin, their synthesis and use. These compounds exhibit preferable biological properties for use in anti-neoplasm therapy.
    Type: Application
    Filed: August 10, 2021
    Publication date: March 17, 2022
    Inventors: Lech KOZERSKI, Beata NAUMCZUK, Jerzy SITKOWSKI, Elzbieta BEDNAREK, Magdalena URBANOWICZ, Wojciech BOCIAN, Katarzyna WIKTORSKA
  • Derivatives of camptothecin, a method of producing them and their use
    Patent number: 9682992
    Abstract: The subject of the present invention are water-soluble derivatives of camptothecin, their synthesis and use. These compounds exhibit preferable biological properties for use in anti-neoplasm therapy.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: June 20, 2017
    Assignees: INSTYTUT CHEMII ORGANICZNEJ POLSKIEJ AKADE, NARODOWY INSTYTUT LEKÓW
    Inventors: Lech Kozerski, Robert Kawęcki, Beata Naumczuk, Karolina Hyz, Wojciech Bocian, Jerzy Sitkowski, Elżbieta Bednarek, Katarzyna Wiktorska, Katarzyna Lubelska
  • DERIVATIVES OF CAMPTOTHECIN, A METHOD OF PRODUCING THEM AND THEIR USE
    Publication number: 20150266888
    Abstract: The subject of the present invention are water-soluble derivatives of camptothecin, their synthesis and use. These compounds exhibit preferable biological properties for use in anti-neoplasm therapy.
    Type: Application
    Filed: October 25, 2013
    Publication date: September 24, 2015
    Applicants: Narodowy Instytut Leków, Instytut Chemii Organicznej Polskiej Akademii Nauk
    Inventors: Lech Kozerski, Robert Kawecki, Beata Naumczuk, Karolina Hyz, Wojciech Bocian, Jerzy Sitkowski, Elzbieta Bednarek, Katarzyna Wiktorska, Katarzyna Lubelska
  • Inhibitor of DD-peptidase and its use as antibiotic or anticancer drug
    Patent number: 8344146
    Abstract: A new compound is revealed and the strain of Streptomyces sp. producing it, which may be used in the production of drugs (Formula I).
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: January 1, 2013
    Assignee: Narodowy Instytut Zdrowia Publicznego-Panstwowy Zaklad Higieny
    Inventors: Jolanta Solecka, Lech Kozerski
  • NEW INHIBITOR OF DD-PEPTIDASE AND ITS USE AS ANTIBIOTIC OR ANTICANCER DRUG
    Publication number: 20100286196
    Abstract: A new compound is revealed and the strain of Streptomyces sp. producing it, which may be used in the production of drugs (Formula I).
    Type: Application
    Filed: August 27, 2008
    Publication date: November 11, 2010
    Inventors: Jolanta Solecka, Lech Kozerski
  • Derivatives of genistein
    Patent number: 5637703
    Abstract: The invention concerns chemical compounds, derivatives of genistein, which exhibit pronounced immunosuppressant and antitumor activity. In particular, the invention concerns compounds having general formula 1, where R.sup.1, R.sup.2, R.sup.3 are the same or different, R.sup.1 denotes hydrogen or alkyl, R.sup.2 and R.sup.3 are the same or different and denote hydrogen, alkyl or aryl, or R.sup.2 and R.sup.3 are taken together with the nitrogen to which they are connected to form a heterocycle ring.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: June 10, 1997
    Assignee: Drug Institute
    Inventors: Aleksander P. Mazurek, Krzysztof Biniecki, Lech Kozerski