Patents by Inventor Leda MANNENT

Leda MANNENT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CHRONIC SPONTANEOUS URTICARIA BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20230146317
    Abstract: Methods for treating or preventing chronic spontaneous urticaria in a subject are provided. Methods comprising administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof, are provided.
    Type: Application
    Filed: July 25, 2022
    Publication date: May 11, 2023
    Inventors: Nikhil Amin, Elizabeth Laws, Leda Mannent, Allen Radin, Aleksandra Stjepanovic, Naimish Patel, Heribert Staudinger
  • METHODS FOR TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20220204631
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: November 23, 2021
    Publication date: June 30, 2022
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist
    Patent number: 11214621
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: January 4, 2022
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING ACTIVE EOSINOPHILIC ESOPHAGITIS
    Publication number: 20210363237
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4/interleukin-13 (IL-4/IL-13) pathway inhibitor such as an anti-IL-4R antibody.
    Type: Application
    Filed: June 4, 2021
    Publication date: November 25, 2021
    Inventors: Allen RADIN, Jennifer D. Hamilton, Leda Mannent
  • METHODS FOR TREATING EOSINOPHILIC ESOPHAGITIS BY ADMINISTERING AN IL-4R INHIBITOR
    Publication number: 20210363264
    Abstract: The present disclosure provides methods for treating, preventing, or ameliorating one or more symptoms of eosinophilic esophagitis in an adolescent or adult subject by administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) inhibitor, such as an anti-IL-4R antibody or antigen-binding fragment thereof.
    Type: Application
    Filed: May 21, 2021
    Publication date: November 25, 2021
    Inventors: Jennifer D. HAMILTON, Jennifer MALONEY, Leda MANNENT, Marcella RUDDY
  • Methods for treating active eosinophilic esophagitis
    Patent number: 11053309
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4/interleukin-13 (IL-4/IL-13) pathway inhibitor such as an anti-IL-4R antibody.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: July 6, 2021
    Assignees: Regeneron Pharmaceuticals, Inc., Sanofi Biotechnology
    Inventors: Allen Radin, Jennifer D. Hamilton, Leda Mannent
  • METHODS FOR TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20190040147
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: July 18, 2018
    Publication date: February 7, 2019
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING ACTIVE EOSINOPHILIC ESOPHAGITIS
    Publication number: 20190040126
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4/interleukin-13 (IL-4/IL-13) pathway inhibitor such as an anti-IL-4R antibody.
    Type: Application
    Filed: August 3, 2018
    Publication date: February 7, 2019
    Inventors: Allen RADIN, Jennifer D. HAMILTON, Leda MANNENT
  • METHODS FOR TREATING NASAL POLYPOSIS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20190040146
    Abstract: The present invention provides methods for treating nasal polyposis. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: July 18, 2018
    Publication date: February 7, 2019
    Inventors: Leda Mannent, Gianluca Pirozzi, Allen Radin, Namita A. Gandhi, Robert Evans
  • Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist
    Patent number: 10066017
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: September 4, 2018
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • Methods for treating nasal polyposis by administering an IL-4R antagonist
    Patent number: 10059771
    Abstract: The present invention provides methods for treating nasal polyposis. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: August 28, 2018
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Leda Mannent, Gianluca Pirozzi, Allen Radin, Namita A. Gandhi, Robert Evans
  • METHODS FOR TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20160185866
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: November 13, 2015
    Publication date: June 30, 2016
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING NASAL POLYPOSIS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20150017182
    Abstract: The present invention provides methods for treating nasal polyposis. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: June 20, 2014
    Publication date: January 15, 2015
    Inventors: Leda MANNENT, Gianluca PIROZZI, Allen RADIN, Namita A. GANDHI, Robert EVANS