Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

Abstract: Aspects of the subject disclosure may include, for example generating, by a first Core Intelligent Controller (CIC) comprising a first processing system including a first processor, first data indicative of one or more first control functions that have been carried out by the first CIC, the first CIC being part of a wireless communication system; communicating, by the first CIC to a Service Intelligent Controller (SIC) comprising a second processing system including a second processor, the first data, the SIC being part of the wireless communication system; generating, by a first RAN Intelligent Controller (RIC) comprising a third processing system including a third processor, second data indicative of one or more first radio access functions that have been carried out by the first RIC, the first RIC being part of the wireless communication system; communicating, by the first RIC to the SIC, the second data; generating, by the SIC, third data, the generating of the third data being based at least in part upon

Abstract: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds.

Abstract: A method being implemented via execution of computing instructions configured to run at one or more processors. The method can include determining a primary store and one or more secondary stores for pickup of an order of a user, based at least in part on a pickup type of the order. The method also can include determining real-time availabilities of first time slots at the primary store and real-time availabilities of second time slots at the one or more secondary stores. The method additionally can include generating a list of available time slots comprising at least a portion of the first time slots at the primary store and at least a portion of the second time slots at the one or more secondary stores, based at least in part on the real-time availabilities of the first time slots at the primary store and the real-time availabilities of the second time slots at the one or more secondary stores.

Abstract: A message processing facility is described. The facility receives user input defining a textual message intended for an addressee service principal. Before sending the defined textual message, the facility analyzes the defined textual message to determine a textual message category to which the defined textual message belongs among a plurality of textual message categories.

Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform: receiving, from one or more electronic devices of one or more users, one or more orders for pickup at a location during a first window of time; at a first time during the first window of time, determining when a designated pickup area at the location exceeds a predetermined level of congestion using: (1) continuously received mobile check-ins at the location; and (2) congestion data of the designated pickup area at the location; and when the designated pickup area at the location does not exceed the predetermined level of congestion during the first window of time, as determined at the first time, causing a pickup electronic device of a pickup to display a pickup request at the location to fulfill at least one order of the one or more orders during the first window of time. Other embodiments are disclosed herein.

Abstract: In some examples, an apparatus can include a syringe body including an electrical interface at a side surface of the syringe body, an interface at an end of the syringe body including an output at a distal surface of the syringe body, a print material particles reservoir located in the syringe body, and a structure to adapt a volume of the print material particles reservoir to move print material particles out of the print material particles reservoir through the output, where in response to the volume adapting structure moving from a first position to a second position, a signal is transmitted by the electrical interface.

Abstract: A dashboard capable of extracting skills in jobs and analyzing those skills for other jobs is disclosed. It utilizes multiple API and datasets from across the world that continue to update over time, showing the current description regardless of location or region. This gives the user the best information possible to identify what jobs within the company have the easiest chance to transition into another job.

Abstract: A lightweight vehicle includes a pair of rear wheel assemblies, one or more front wheel assemblies, a universal assembly platform, and forward facing seating. The universal assembly platform includes a planar main vehicle chassis, a front suspension system connected to the planar main vehicle chassis and to which the one or more front wheel assemblies is mounted, and a rear suspension system connected to the planar main vehicle chassis and to which the pair of rear wheel assemblies is mounted. A front distal end of the one or more front wheel assemblies is longitudinally forward of a front end of the planar main vehicle chassis. The forward facing seating is mounted to the planar main vehicle chassis such that a portion of a seat bottom of the forward facing seating is located longitudinally rearward of an axis extending through a center of the pair of rear wheel assemblies.

Abstract: An insert for an arthropod trapping device. The insert comprising a substrate and a frame for supporting the substrate, where a surface of the substrate has an adhesive disposed thereon, an optional mounting bracket spaced apart from the adhesive surface of the insert and located at a first end of the insert, and an optional graspable tab extending from the frame at a second end of the insert.

Abstract: An apparatus and method for trapping particles disposed in a fluid. The apparatus may comprise one or more cavities disposed axially along a length of a tubular housing, one or more connecting components disposed at opposing ends of the housing, and may optionally comprise a check valve system. Alternate embodiments are provided for forming each of the one or more cavities, which may comprise a combination of a cavity frame and cavity surface. The method may comprise flowing a fluid into a first end of a particle trap apparatus at a rate of fluid flow, directing the fluid flow at least partially through one or more cavity sub-assemblies disposed in the particle trap apparatus, collecting the particulate matter in one or more of the cavity sub-assemblies when the rate of fluid flow may slow or become suspended, and clearing collected particles from the one or more cavity sub-assemblies upon restoration of fluid flow in a primary direction of travel.

Abstract: Disclosed herein are systems, apparatuses, methods, and non-transitory computer readable media related to display constructs that can be fixed or movable. The display constructs can be configured to facilitate media display at opposite sides. The display constructs may be is at least partially transparent and can be viewed therethrough. Various interactive capabilities with the display construct are disclosed, as well as various installation component and kits. Further disclosed are wireless chargers embedded in fixtures and/or real assets of a facility.

Abstract: A lightweight vehicle includes a first wheel assembly including a first wheel rotatable about an axis, a second wheel assembly including a second wheel rotatable about the axis, a platform including a chassis and a rear suspension assembly coupling the first wheel assembly and the second wheel assembly to the chassis, a first seat coupled to the chassis, and a second seat coupled to the chassis rearward of the first seat. At least a portion of the chassis has a planar shape. The second seat includes a bottom and a back. The back is positioned rearward of at least a portion of the bottom such that the second seat defines a forward-facing seating. At least a portion of the bottom of the second seat is positioned longitudinally rearward of a plane extending vertically upward from the axis about which the first wheel and the second wheel are rotatable.

Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

Abstract: A lightweight vehicle includes a pair of rear wheel assemblies, one or more front wheel assemblies, a universal assembly platform, and forward facing seating. The universal assembly platform includes a main vehicle chassis, a front suspension system coupled to the main vehicle chassis and to which the one or more front wheel assemblies is mounted, and a rear suspension system coupled to the main vehicle chassis and to which the pair of rear wheel assemblies is mounted. A front distal end of the one or more front wheel assemblies is longitudinally forward of a front end of the main vehicle chassis. The forward facing seating is mounted to the main vehicle chassis such that a portion of a seat bottom of the forward facing seating is located longitudinally rearward of an axis extending through a center of the pair of rear wheel assemblies.

Abstract: A laminate film, package formed from the laminate film, and method for constructing the laminate film are provided. The laminate film includes a barrier layer, sealing layer, bonding layer, and thermochromic ink layer. The thermochromic ink layer includes thermochromic ink such that the thermochromic ink is trapped between the barrier layer and sealing layer. The thermochromic ink has a first visual appearance and is adapted to permanently change to a second visual appearance upon exposure to certain pre-determined conditions during a sealing process and to maintain permanence of the second visual appearance during post-sealing processes. The package includes the laminate film, a substrate, and a packaged article. The edges of the laminate film are sealed to the substrate and form a seal. The seal forms a perimeter about the article and has the second visual appearance, including a different color, such that the integrity of the seal is quickly and confidently verifiable by an observer.

Abstract: A fluid management and medical device system may include a fluid management system and a medical device having one or more sensors proximate the distal end of the elongate shaft of the medical device. The controller of the fluid management system may be configured to calculate a fluid deficit when the distal end of the elongate shaft is disposed within a patient and configured to automatically pause fluid deficit calculation when the distal end of the elongate shaft is removed from the patient. In some instances the controller is configured to calculate the fluid deficit using rotational speed of the inflow pump in combination with a difference between a change in weight of a fluid supply source supplying fluid to the fluid management system and a change in weight of a collection container collecting fluid from the fluid management system.

Abstract: A tubing assembly is provided that can comprise a plurality of tubes or lumens that can be disposed within a head of a peristaltic pump. The tubing assembly can provide a flow rate or volume capacity that is generally equal to or greater than that achieved with a comparable prior art tube while operating at higher pressures than that possible using the prior art tube. Further, in accordance with some embodiments, the tubing assembly can achieve a longer working life than a comparable prior art tube, and the load on the pump motor can be reduced such that the pump life is increased and/or a larger pump motor is not required to achieve such advantageous results.

Abstract: Disclosed embodiments include apparatuses, systems, and methods for facilitating surgical anastomosis between bodily passages. In an illustrative embodiment, an eversion mechanism is configured to partially evert a distal portion of an opening of a receiving passage and further configured to leave a proximal portion of the opening of the receiving passage in a non-everted position. A donor support mechanism is configured to partially evert a distal portion of an opening at an end of a donor passage and further configured to leave a first proximal portion of the end of the donor passage in a non-everted position. The donor support mechanism is further configured to form a passage juncture at the end of the donor passage and the opening of the receiving passage. A suturing mechanism is configured to motivate a filament through a generally helical path around the passage juncture to suture the donor passage to the receiving passage.