Patents by Inventor Lee Adam Wheeler

Lee Adam Wheeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition and method for oligonucleotide delivery
    Patent number: 11384356
    Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: July 12, 2022
    Assignee: The Children's Medical Center Corporation
    Inventors: Judy Lieberman, Lee Adams Wheeler
  • Methods and compositions for the treatment of cancer
    Patent number: 11180762
    Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: November 23, 2021
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Judy Lieberman, Adi Gilboa-Geffen, Lee Adam Wheeler
  • COMPOSITION AND METHOD FOR OLIGONUCLEOTIDE DELIVERY
    Publication number: 20190359987
    Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.
    Type: Application
    Filed: May 24, 2019
    Publication date: November 28, 2019
    Applicant: The Children's Medical Center Corporation
    Inventors: Judy Lieberman, Lee Adams Wheeler
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
    Publication number: 20190309297
    Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.
    Type: Application
    Filed: May 10, 2019
    Publication date: October 10, 2019
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Judy LIEBERMAN, Adi GILBOA-GEFFEN, Lee Adam WHEELER
  • Methods and compositions for the treatment of cancer
    Patent number: 10385343
    Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: August 20, 2019
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Judy Lieberman, Adi Gilboa-Geffen, Lee Adam Wheeler
  • Composition and method for oligonucleotide delivery
    Patent number: 10378016
    Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: August 13, 2019
    Assignee: Children's Medical Center Corporation
    Inventors: Judy Lieberman, Lee Adam Wheeler
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
    Publication number: 20170275629
    Abstract: Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.
    Type: Application
    Filed: August 28, 2015
    Publication date: September 28, 2017
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Judy LIEBERMAN, Adi GILBOA-GEFFEN, Lee Adam WHEELER
  • COMPOSITION AND METHOD FOR OLIGONUCLEOTIDE DELIVERY
    Publication number: 20130338215
    Abstract: The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.
    Type: Application
    Filed: December 6, 2011
    Publication date: December 19, 2013
    Inventors: Judy Lieberman, Lee Adam Wheeler