Patents by Inventor Lee Ayres

Lee Ayres has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220143275
    Abstract: A medical device to be inserted into a body at depths greater than 5 cm, includes an echogenic coating composition including: (i) a polymer matrix and (ii) an amount of ultrasound-reflective microparticles having a diameter that is at least 10 and at most 250 ?m in size, with a defined relationship between the particle size, expressed as D 50, and the surface density. A method for ultrasound detection of a medical device at a scan depth greater than 5 cm includes providing the medical device with the echogenic coating composition. An echogenic assembly includes the medical device having the echogenic coating composition and a convex probe.
    Type: Application
    Filed: March 26, 2020
    Publication date: May 12, 2022
    Inventors: Lee Ayres, Yiyuan Lin, Hendricus Philip Breek
  • Publication number: 20220088277
    Abstract: An echogenic coating composition on a medical device to be inserted into a body at depths greater than 5 cm includes: (i) a polymer matrix and (ii) an amount of ultrasound-reflective microparticles having a diameter that is at least 10 and at most 250 ?m in size, with a defined relationship between the particle size, expressed as D50, and the surface density. A method for ultrasound detection of a medical device at a scan depth greater than 5 cm includes: providing the medical device with the echogenic coating composition and to an echogenic assembly including the medical device and a convex probe.
    Type: Application
    Filed: March 26, 2020
    Publication date: March 24, 2022
    Inventors: Lee Ayres, Yiyuan Lin, Hendricus Philip Breek
  • Publication number: 20220061881
    Abstract: A sheath assembly configured to be positioned over a needle of a needle assembly or over a needle of a catheter assembly includes an elongated tube which defines a bore and an echogenic structure and a connector configured to be fixated to an outside of the cannula wall of the needle, thereby fixating the sheath assembly.
    Type: Application
    Filed: February 28, 2020
    Publication date: March 3, 2022
    Inventors: Hendricus Philip Breek, Lee Ayres
  • Patent number: 10245356
    Abstract: The invention provides medical devices comprising improved non-uniform coatings for ultrasound detection, which provide optimal ultrasound images. Methods for preparing such devices are also provided.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: April 2, 2019
    Assignee: ENCAPSON B.V.
    Inventors: Lee Ayres, David Asrian, Johannes Antonius Opsteen, Dennis Manuel Vriezema
  • Patent number: 10166005
    Abstract: The disclosure provides medical devices comprising improved coatings for ultrasound detection, which provide optimal ultrasound images. Methods for preparing such devices are also provided.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: January 1, 2019
    Assignee: Encapson B.V.
    Inventors: Dennis Manuel Vriezema, Lee Ayres, David Asrian, Johannes Antonius Opsteen
  • Publication number: 20170258450
    Abstract: The disclosure provides medical devices comprising improved coatings for ultrasound detection, which provide optimal ultrasound images. Methods for preparing such devices are also provided.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 14, 2017
    Applicant: ENCAPSON B.V.
    Inventors: Dennis Manuel Vriezema, Lee Ayres, David Asrian, Johannes Antonius Opsteen
  • Patent number: 9681852
    Abstract: The disclosure provides medical devices comprising improved coatings for ultrasound detection, which provide optimal ultrasound images. Methods for preparing such devices are also provided.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: June 20, 2017
    Assignee: Encapson B.V.
    Inventors: Dennis Manuel Vriezema, Lee Ayres, David Asrian, Johannes Antonius Opsteen
  • Publication number: 20170043063
    Abstract: The invention provides medical devices comprising improved non-uniform coatings for ultrasound detection, which provide optimal ultrasound images. Methods for preparing such devices are also provided.
    Type: Application
    Filed: April 30, 2015
    Publication date: February 16, 2017
    Inventors: Lee Ayres, David Asrian, Johannes Antonius Opsteen, Dennis Manuel Vriezema
  • Publication number: 20150351721
    Abstract: The disclosure provides medical devices comprising improved coatings for ultrasound detection, which provide optimal ultrasound images. Methods for preparing such devices are also provided.
    Type: Application
    Filed: October 31, 2013
    Publication date: December 10, 2015
    Inventors: Dennis Manuel Vriezema, Lee Ayres, David Asrian, Johannes Antonius Opsteen
  • Publication number: 20140207000
    Abstract: The disclosure relates to a coating for improving the ultrasound visibility of a device, the coating being made of a matrix material comprising at least one contrast agent, wherein the at least one contrast agent is a plurality of gas-filled microparticles. Moreover, this disclosure relates to an ultrasonic contrast agent-containing coating for a device. In addition, the herein-described disclosure relates to a method for preparing a microparticle, a method for preparing a coating, and a method for coating a device as well as the coated device.
    Type: Application
    Filed: April 25, 2012
    Publication date: July 24, 2014
    Applicant: ENCAPSON B.V.
    Inventors: Dennis Manuel Vriezema, Lee Ayres, Abraham Reiner Keereweer
  • Publication number: 20120083734
    Abstract: The invention provides a solution to the above mentioned problem in that it provides a catheter balloon comprising a flexible coating on its outer surface wherein a plurality of microparticles are contained wherein said coating comprises a material selected from the group consisting of poly(N-vinyl-pirrolidone, poly(N-vinyl-pirrolidone-co-butylacrylate), poly(-vinyl pyridine), polyacrylamides, e.g. poly(N-isopropylacrylamide), poly(amido-amines), poly(ethylene imine), poly(ethylene oxide-block-propylene oxide), poly(ethylene oxide-block-propylene oxide-block-ethylene oxide), poly(styrene-block-isobutylene-block-styrene), poly(hydroxystyrene-block-isobutylene-block-hydroxystyrene), polydialkylsiloxanes, polysaccharides, polyacrylates and polyalkylmethacrylates, e.g. polymethylmethacrylate and poly(2-hydroxyethylmethacrylate) and wherein said microparticles comprise a material selected from the group consisting of polyesters, e.g.
    Type: Application
    Filed: May 17, 2010
    Publication date: April 5, 2012
    Applicant: Encapson B.V.
    Inventors: Lee Ayres, Dennis Manuel Vriezema, Johannes Hendrikus Leonardus Hanssen, Johannes Antonius Opsteen
  • Publication number: 20090312741
    Abstract: The invention provides a bioresorbable composition comprising a mixture of at least one polymer and capsules, which capsules comprise an inner part which is encapsulated by a shell which shell is at least partly decomposable by application of an external stimulation source. The invention also relates to a medical device comprising said composition.
    Type: Application
    Filed: September 19, 2007
    Publication date: December 17, 2009
    Applicant: STICHTING KATHOLIEKE UNIVERSITEIT, MORE PARTICULAR
    Inventors: Nicolaas Jacobus Joseph Verdonschot, Jan Cornelis Maria van Hest, Pieter Buma, Lee Ayres, Dennis M. Vriezema