Abstract: The present disclosure is an electronic device that senses when the ignition of a vehicle has been turned off and automatically delivers a reminder, audibly, visibly, haptically or through other electronic means, to remind the driver to check the interior for any young passengers, pets, or valuables before exiting the vehicle. After this message is delivered, the device will continue to actively monitor the interior of the vehicle for both extreme compartment temperatures and any activity that indicates that a person or animal is still present inside of the vehicle. It will also sense any case where an individual has entered the vehicle unattended without the operator's knowledge and the vehicle is not started within a reasonable amount of time as expected. Once a determination for either of these situations has been made, an alert is delivered electronically to the vehicle owner or any other relevant parties in the vicinity.

Abstract: A system for preparing compounded medication doses is disclosed. The system includes a medication compounding workstation configured to receive a medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare a compounded medication dose specified by the medication dose order. The example workstation is also configured to display, on a display screen to a pharmacy operator, information related to the set of steps for preparing the compounded medication dose and receive input related to the preparation of the compounded medication dose including at least medication information from at least one source medication container. The workstation verifies completion for each step for preparing the compounded medication dose.

Abstract: A system for preparing compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a batch compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare compounded medication doses specified by the batch compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the compounded medication doses and receive input related to the preparation of the compounded medication doses including at least medication information scanned from at least one source medication container and a digital image from a digital camera. The workstation verifies completion for each step before allowing the pharmacy operator to move to a next step to prepare the compounded medication doses.

Abstract: A system for preparing compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a batch compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare compounded medication doses specified by the batch compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the compounded medication doses and receive input related to the preparation of the compounded medication doses including at least medication information scanned from at least one source medication container and a digital image from a digital camera. The workstation verifies completion for each step before allowing the pharmacy operator to move to a next step to prepare the compounded medication doses.

Abstract: A system for preparing patient-specific compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a patient-specific compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare a patient-specific compounded medication dose specified by the patient-specific compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the patient-specific compounded medication dose and receive input related to the preparation of the patient-specific compounded medication dose including at least medication information scanned from at least one source medication container and a digital image from a digital camera.

Abstract: A system for preparing and managing patient-specific dose orders includes an order processing server configured to receive the patient-specific dose orders, define a queue of dose orders and distribute the dose orders to at least one dose preparation station. The dose preparation station is in bi-directional communication with the order processing server and has an interface for providing an operator with a protocol associated with each received drug order and specifying a set of steps to fill the drug order. Steps to fill the drug order are captured at the station and a display, positionable independent of the station outputs the dose order queue and metrics concerning activity at the dose preparation station. Systems for preparing patient-specific doses and a method for telepharmacy in which data captured while following the protocol are provided to a remote site for review and approval by a pharmacist.

Abstract: A system for preparing patient-specific compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a patient-specific compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare a patient-specific compounded medication dose specified by the patient-specific compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the patient-specific compounded medication dose and receive input related to the preparation of the patient-specific compounded medication dose including at least medication information scanned from at least one source medication container and a digital image from a digital camera.

Abstract: A system for preparing and managing patient-specific dose orders includes an order processing server configured to receive the patient-specific dose orders, define a queue of dose orders and distribute the dose orders to at least one dose preparation station. The dose preparation station is in bi-directional communication with the order processing server and has an interface for providing an operator with a protocol associated with each received drug order and specifying a set of steps to fill the drug order. Steps to fill the drug order are captured at the station and a display, positionable independent of the station outputs the dose order queue and metrics concerning activity at the dose preparation station. Systems for preparing patient-specific doses and a method for telepharmacy in which data captured while following the protocol are provided to a remote site for review and approval by a pharmacist.

Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin ?5?1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-?5?1 antibodies or antigen binding portions thereof described herein.

Abstract: A system for preparing and managing patient-specific dose orders includes an order processing server configured to receive the patient-specific dose orders, define a queue of dose orders and distribute the dose orders to at least one dose preparation station. The dose preparation station is in bi-directional communication with the order processing server and has an interface for providing an operator with a protocol associated with each received drug order and specifying a set of steps to fill the drug order. Steps to fill the drug order are captured at the station and a display, positionable independent of the station outputs the dose order queue and metrics concerning activity at the dose preparation station. Systems for preparing patient-specific doses and a method for telepharmacy in which data captured while following the protocol are provided to a remote site for review and approval by a pharmacist.

Abstract: A system for preparing and managing patient-specific dose orders includes an order processing server configured to receive the patient-specific dose orders, define a queue of dose orders and distribute the dose orders to at least one dose preparation station. The dose preparation station is in bi-directional communication with the order processing server and has an interface for providing an operator with a protocol associated with each received drug order and specifying a set of steps to fill the drug order. Steps to fill the drug order are captured at the station and a display, positionable independent of the station outputs the dose order queue and metrics concerning activity at the dose preparation station. Systems for preparing patient-specific doses and a method for telepharmacy in which data captured while following the protocol are provided to a remote site for review and approval by a pharmacist.

Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin ?5?1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-?5?1 antibodies or antigen binding portions thereof described herein.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device. At least one of the stations includes a peripheral device for performing at least one operation and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system includes a master controller that tracks and controls the movement of the transporting device and operation of equipment at one or more stations.

Abstract: A system for preparing and managing patient-specific dose orders includes an order processing server configured to receive the patient-specific dose orders, define a queue of dose orders and distribute the dose orders to at least one dose preparation station. The dose preparation station is in bi-directional communication with the order processing server and has an interface for providing an operator with a protocol associated with each received drug order and specifying a set of steps to fill the drug order. Steps to fill the drug order are captured at the station and a display, positionable independent of the station outputs the dose order queue and metrics concerning activity at the dose preparation station. Systems for preparing patient-specific doses and a method for telepharmacy in which data captured while following the protocol are provided to a remote site for review and approval by a pharmacist.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device. At least one of the stations includes a peripheral device for performing at least one operation and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system includes a master controller that tracks and controls the movement of the transporting device and operation of equipment at one or more stations.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Abstract: An aeronautical navigation plotting instrument is provided that includes a plotting frame and a compass rose attached to the plotting frame. The compass rose includes angular markings incrementally disposed thereon about a center of the compass for defining the angular orientation of the compass. A longitudinal slot is aligned with the center of the compass rose and extends through the plotting frame to define an opening for receiving a writing instrument. A plurality of first radial openings extends through the plotting frame to allow a writing instrument to extend therethrough. Each first radial opening is incrementally spaced from an originating opening in the plotting frame to form a plurality of incrementally spaced radial distances from the originating opening.

Abstract: A housing structure for improving air flow to the intake manifold of an internal combustion engine is claimed. The present invention is a replacement part for a factory-installed mass air flow sensor housing and is designed to allow for larger air flow through the housing through the use of a bypass air passage or calibration tube that reduces air flow as experienced by the mass air flow sensor. The calibration tube reduces air flow across the sensor with a larger bore on its inlet and a restriction in its outlet. The calibration tube is angled to reduce back flow from the engine.

Abstract: Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.