Patents by Inventor Lee C. Makowski

Lee C. Makowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and system for allowing increased migration across a lipid bilayer
    Patent number: 5284588
    Abstract: A method and system are disclosed for allowing significantly increased migration of a molecule across a lipid bilayer membrane. The method includes combining an aqueous solvent medium, in which the lipid bilayer membrane and the molecule are disposed, with a solute. The aqueous solvent medium, the lipid bilayer membrane and the molecule are then exposed to a sufficient partial pressure of the solute to cause the solute to dissolve in the aqueous solvent medium, whereby a significant portion of the solute migrates to the hydrophobic fatty acyl portion of the lipid bilayer membrane. The solute thereby allows a significantly increased migration of the molecule across the lipid bilayer membrane.
    Type: Grant
    Filed: January 8, 1992
    Date of Patent: February 8, 1994
    Assignees: Trustees of Boston University, General Electric Company
    Inventors: Lee C. Makowski, Hoshang F. Batliwala