Patents by Inventor Lee Chao

Lee Chao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240112928
    Abstract: A trimming method is provided. The trimming method includes the following steps. A first wafer including a substrate and a device layer over a first side of the substrate is provided. The first wafer is bonded to a second wafer with the first side of the substrate facing toward the second wafer. An edge trimming process is performed to remove a trimmed portion of the substrate from a second side opposite to the first side vertically downward toward the first side in a first direction along a perimeter of the substrate, wherein the edge trimming process results in the substrate having a flange pattern laterally protruding from the device layer and laterally surrounding an untrimmed portion of the substrate along a second direction perpendicular to the first direction.
    Type: Application
    Filed: January 10, 2023
    Publication date: April 4, 2024
    Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: An-Hsuan Lee, Chen-Hao Wu, Chun-Hung Liao, Huang-Lin Chao
  • Patent number: 11939584
    Abstract: Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.
    Type: Grant
    Filed: July 31, 2021
    Date of Patent: March 26, 2024
    Assignee: PRECIGEN, INC.
    Inventors: Xinhua Zhao, Mark Anton Held, Tina Huynh, Lily Yuin Chao, Na Trinh, Matthias Helmut Schmalisch, Bryan Yeh, James Kealey, Kevin Lee Dietzel
  • Patent number: 11942373
    Abstract: A semiconductor device structure is provided. The semiconductor device structure includes a first fin, a second fin and a third fin therebetween. A first insulating structure includes a first insulating layer formed between the first and third fins, a capping structure covering the first insulating layer, a first insulating liner covering sidewall surfaces of the first insulating layer and the capping structure and a bottom surface of the first insulating layer, and a second insulating liner formed between the first insulating liner and the first fin and between the first insulating liner and the third fin. The second insulating structure includes a second insulating layer formed between the second fin and the third fin and a third insulating liner formed between the second insulating layer and the second fin and between the second insulating layer and the third fin.
    Type: Grant
    Filed: May 10, 2023
    Date of Patent: March 26, 2024
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Chu-An Lee, Chen-Hao Wu, Peng-Chung Jangjian, Chun-Wen Hsiao, Teng-Chun Tsai, Huang-Lin Chao
  • Publication number: 20220148591
    Abstract: A method for programming a stimulation device of a stimulation system using a programming device includes providing a set of programming commands for the programming device that include a first programming command increasing a stimulation amplitude and a second programming command includes decreasing the stimulation amplitude; receiving a verbal communication by a voice command handler of the programming device or in communication with the programming device; determining whether the verbal communication is a trigger word and, when the verbal communication is the trigger word, entering a triggered state, wherein, after entering the triggered state, the programming device remains in the triggered state until a one of at least one stop condition is met; and, when in the triggered state, determining whether the verbal communication is one of the programming commands and, when the verbal communication is one of the programming commands, executing the one of the programming commands.
    Type: Application
    Filed: October 28, 2021
    Publication date: May 12, 2022
    Inventors: Jimmy Lee Chao, Vishal Jagannathan, Eugene Mesina, Travis McCoy
  • Publication number: 20200188532
    Abstract: Methods for treating age-related eye diseases or conditions are provided. Methods for treating an age-related eye disease or condition in a subject by administering one or more demethylation compounds or agents are provided.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Inventors: Dorota Skowronska-Krawczyk, Daniel Lee Chao, Daniel Chen
  • Patent number: 10632211
    Abstract: Methods for treating age-related eye diseases or conditions are provided. Methods for treating an age-related eye disease or condition in a subject by administering one or more demethylation compounds or agents are provided.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: April 28, 2020
    Assignee: The Regents of the University of California
    Inventors: Dorota Skowronska-Krawczyk, Daniel Lee Chao, Daniel Chen
  • Publication number: 20190374653
    Abstract: Methods for treating age-related eye diseases or conditions are provided. Methods for treating an age-related eye disease or condition in a subject by administering one or more demethylation compounds or agents are provided.
    Type: Application
    Filed: May 29, 2019
    Publication date: December 12, 2019
    Inventors: Dorota Skowronska-Krawczyk, Daniel Lee Chao
  • Patent number: 7190579
    Abstract: An air purifying data processing system includes a chassis, a planar, a microprocessor and an air purifier. The air purifier produces purified air that is exhausted exterior to the chassis to improve the air quality in the vicinity of the chassis. The air purifier produces an air flow that is preferably in proximity to the microprocessor to facilitate dissipation of heat generated by the microprocessor. The air purifier may be oriented to direct the air flow through an opening in a first face of the chassis. The air purifier may include a high voltage unit to create an electrical discharge within the air purifier. The high voltage unit preferably produces a voltage greater of 8000 V or at an output point of the high voltage unit. The air purifier includes a grounded and electrically conductive grid in the vicinity of the high voltage unit output point.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: March 13, 2007
    Assignee: International Business Machines Corporation
    Inventor: James Lee Chao
  • Patent number: 7161098
    Abstract: A method and system of minimizing sticky keys in an electronic device having a body, circuitry, and a plurality of keypads is disclosed. The method and system comprise providing a protectant coating; and applying the protectant coating on surfaces of both the keypad and also the body to prevent sticking between the mating surfaces. A system and method is added in accordance with the present invention utilizing a protectant on critical surfaces which serves to prevent the residual buildup of contaminants following spills. In so doing the sticky key problem associated with the contaminated buildup is substantially eliminated.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: January 9, 2007
    Assignee: Lenovo (Singapore) Pte. Ltd.
    Inventors: James Lee Chao, Leonard Douglas Hobgood
  • Patent number: 6864093
    Abstract: Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell line, MCF-7, while invasive human breast cancer cell lines MDA-MB-231 and MDA-MB-435s were found not to express either the prostasin protein or the mRNA. A non-invasive human breast cancer cell line, MDA-MB-453, was shown to express prostasin mRNA but not prostasin protein.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: March 8, 2005
    Assignee: University of Central Florida
    Inventors: Karl X. Chai, Li-Mei Chen, Lee Chao, Julie Chao
  • Publication number: 20040206608
    Abstract: A method and system of minimizing sticky keys in an electronic device having a body, circuitry, and a plurality of keypads is disclosed. The method and system comprise providing a protectant coating; and applying the protectant coating on surfaces of both the keypad and also the body to prevent sticking between the mating surfaces. A system and method is added in accordance with the present invention utilizing a protectant on critical surfaces which serves to prevent the residual buildup of contaminants following spills. In so doing the sticky key problem associated with the contaminated buildup is substantially eliminated.
    Type: Application
    Filed: April 2, 2001
    Publication date: October 21, 2004
    Inventors: James Lee Chao, Leonard Douglas Hobgood
  • Patent number: 6747140
    Abstract: The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence in the subject of a tissue kallikrein promoter allele genotype correlated with an increased likelihood of regulating blood pressure with dietary sodium intake, whereby the presence of the genotype identifies the subject as having an increased likelihood of regulating blood pressure by dietary sodium intake.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: June 8, 2004
    Assignee: Medical University of South Carolina
    Inventors: Lee Chao, Julie Chao, Qing Song
  • Patent number: 6716518
    Abstract: A method and system of reversibly absorbing liquid penetrations into electronic devices having a body and circuitry is described. The method and system comprises providing an absorbent sponge membrane structure in sheet-like form. The structure contains a hydrogel-forming core integrated into a blown polymer foam. The method and system includes placing the absorbent structure within the electronic device such that the hydrogel-forming core and blown polymer foam at least partly covers the electronic circuitry to be protected. A method and system in accordance with the present invention has the further advantage that due to the inclusion of the crystals into the open cells of the sponge, that structure is much easier to manufacture into various templates by punching or stamping holes where the keys and other mechanical obstructions such as bosses and supports must be accommodated.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: April 6, 2004
    Assignee: International Business Machines Corporation
    Inventors: James Lee Chao, Charles C. Sloop, III
  • Patent number: 6706483
    Abstract: Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell line, MCF-7, while invasive human breast cancer cell lines MDA-MB-231 and MDA-MB-435s were found not to express either the prostasin protein or the mRNA. A non-invasive human breast cancer cell line. MDA-MB-453, was shown to express prostasin mRNA but not prostasin protein.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: March 16, 2004
    Assignee: University of Central Florida
    Inventors: Karl X. Chai, Li-Mei Chen, Lee Chao, Julie Chao
  • Patent number: 6689614
    Abstract: Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell line, MCF-7, while invasive human breast cancer cell lines MDA-MB-231 and MDA-MB-435s were found not to express either the prostasin protein or the mRNA. A non-invasive human breast cancer cell line, MDA-MB-453, was shown to express prostasin mRNA but not prostasin protein.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: February 10, 2004
    Assignee: University of Central Florida
    Inventors: Karl X. Chai, Li-Mei Chen, Lee Chao, Julie Chao
  • Publication number: 20030157490
    Abstract: The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence in the subject of a tissue kallikrein promoter allele genotype correlated with an increased likelihood of regulating blood pressure with dietary sodium intake, whereby the presence of the genotype identifies the subject as having an increased likelihood of regulating blood pressure by dietary sodium intake.
    Type: Application
    Filed: January 29, 2002
    Publication date: August 21, 2003
    Applicant: Medical University of South Carolina
    Inventors: Lee Chao, Julie Chao, Qing Song
  • Patent number: 6569684
    Abstract: Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell line, MCF-7, while invasive human breast cancer cell lines MDA-MB-231 and MDA-MB-435s were found not to express either the prostasin protein or the mRNA. A non-invasive human breast cancer cell line, MDA-MB-453, was shown to express prostasin mRNA but not prostasin protein.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: May 27, 2003
    Assignee: University of Central Florida
    Inventors: Karl X. Chai, Li-Mei Chen, Lee Chao, Julie Chao
  • Publication number: 20030017324
    Abstract: A method and system of reversibly absorbing liquid penetrations into electronic devices having a body and circuitry is described. The method and system comprises providing an absorbent sponge membrane structure in sheet-like form. The structure contains a hydrogel-forming core integrated into a blown polymer foam. The method and system includes placing the absorbent structure within the electronic device such that the hydrogel-forming core and blown polymer foam at least partly covers the electronic circuitry to be protected. A method and system in accordance with the present invention has the further advantage that due to the inclusion of the crystals into the open cells of the sponge, that structure is much easier to manufacture into various templates by punching or stamping holes where the keys and other mechanical obstructions such as bosses and supports must be accommodated.
    Type: Application
    Filed: July 17, 2001
    Publication date: January 23, 2003
    Applicant: International Business Machines Corporation
    Inventors: James Lee Chao, Charles C. Sloop
  • Patent number: 6398436
    Abstract: The present invention offers an improved method of reversibly absorbing aqueous solution penetrations into electronic equipment. The method comprises providing an absorbent structure having a certain thickness, the thickness defined by the desired or expected use of the electronic equipment such as a computer keyboard, cellular phone, ATM machine keyboard, radios, PDAs, remote controls, and other electronic devices that might be compromised by liquids and aqueous solutions, rain and the like. The absorbent structure comprises at least a water-permeable top sheet, a hydrogel-forming core, and a water-impermeable back sheet. Several layers and combinations of layers may also be provided, depending upon the desired usage.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: June 4, 2002
    Assignee: International Business Machines Corporation
    Inventor: James Lee Chao
  • Patent number: 6376182
    Abstract: The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence in the subject of a tissue kallikrein promoter allele genotype correlated with an increased likelihood of regulating blood pressure with dietary sodium intake, whereby the presence of the genotype identifies the subject as having an increased likelihood of regulating blood pressure by dietary sodium intake.
    Type: Grant
    Filed: January 31, 2000
    Date of Patent: April 23, 2002
    Assignee: Medical University of South Carolina
    Inventors: Lee Chao, Julie Chao, Qing Song