Patents by Inventor Lee E. Babiss

Lee E. Babiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230010886
    Abstract: Compounds of Formula 1 as inhibitors of protein tyrosine phosphatase SHP2 are disclosed. The pharmaceutical compositions comprising compounds of Formula 1, methods of synthesis of these compounds, methods of treatment for diseases associated with the aberrant activity of SHP2 such as cancer using these compounds or compositions containing these compounds are also disclosed.
    Type: Application
    Filed: September 18, 2020
    Publication date: January 12, 2023
    Inventors: Yinong XIE, Lee E. BABISS
  • Publication number: 20200385370
    Abstract: Compounds of Formula I as IRAK4 inhibitors are disclosed. The pharmaceutical compositions comprising compounds of formula I, methods of synthesis of these compounds, methods of treatment for diseases associated with IRAK-4 such as inflammatory diseases and autoimmune diseases using these compounds or compositions containing these compounds are also disclosed.
    Type: Application
    Filed: October 29, 2018
    Publication date: December 10, 2020
    Inventors: Yinong XIE, Lee E BABISS
  • Patent number: 10561655
    Abstract: Compounds of Formula 1 as inhibitors of protein tyrosine phosphatase SHP2 are disclosed. The pharmaceutical compositions comprising compounds of Formula 1, methods of synthesis of these compounds, methods of treatment for diseases associated with the aberrant activity of SHP2 such as cancer using these compounds or compositions containing these compounds are also disclosed.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: February 18, 2020
    Assignee: SYNBLia Therapeutics, Inc.
    Inventors: Yinong Xie, Lee E. Babiss
  • Publication number: 20190290649
    Abstract: Compounds of Formula 1 as inhibitors of protein tyrosine phosphatase SHP2 are disclosed. The pharmaceutical compositions comprising compounds of Formula 1, methods of synthesis of these compounds, methods of treatment for diseases associated with the aberrant activity of SHP2 such as cancer using these compounds or compositions containing these compounds are also disclosed.
    Type: Application
    Filed: March 18, 2019
    Publication date: September 26, 2019
    Inventors: Yinong Xie, Lee E. Babiss