Patents by Inventor Lee Fisher

Lee Fisher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150003723
    Abstract: A system and method of detecting one or more objects in a three-dimensional point cloud scene are provided. The method includes receiving a three-dimensional point cloud scene, the three-dimensional point cloud scene comprising a plurality of points; classifying at least a portion of the plurality of points in the three-dimensional point cloud into two or more categories by applying a classifying-oriented three-dimensional local descriptor and learning-based classifier; extracting from the three-dimensional point cloud scene one or more clusters of points utilizing the two or more categories by applying at least one of segmenting and clustering; and matching the extracted clusters with objects within a library by applying a matching-oriented three-dimensional local descriptor.
    Type: Application
    Filed: June 27, 2013
    Publication date: January 1, 2015
    Inventors: Jing HUANG, Suya YOU, Amir ANVAR, Christopher Lee FISHER
  • Patent number: 8816058
    Abstract: Isolated polynucleotides are provided which encode antibody VH and VL polypeptides, and anti-CD100 antibodies and antigen-binding fragments thereof. In another aspect, the invention provides a vector comprising a polynucleotide of the invention. In another aspect, the invention provides a host cell comprising the vector of the invention. In another aspect, the invention provides a method of producing an antibody of the invention, e.g., for treating diseases associated with CD100, including certain autoimmune diseases, inflammatory diseases, and cancers.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: August 26, 2014
    Assignee: Vaccinex, Inc.
    Inventors: Ernest S. Smith, Terrence Lee Fisher
  • Publication number: 20140094872
    Abstract: The present invention relates a system that can configure a stimulus for functional electrical stimulation (“FES”) to maintain a constant muscle force while delaying the onset of muscle fatigue and a related method of use. The stimulus can be delivered to a nerve via a set of multiple electrode contacts according to a stimulation parameter that maximizes a joint moment associated with the stimulus and minimizes the overlap between pairs of contacts. The joint moment can be related to the muscle force, and the overlap can be related to the onset of muscle fatigue.
    Type: Application
    Filed: December 10, 2013
    Publication date: April 3, 2014
    Applicant: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Lee Fisher, Ronald Triolo, Dustin J. Tyler
  • Publication number: 20140031910
    Abstract: Systems and methods are provided for stimulating motor units. An electrode array includes a plurality of electrodes configured to provide stimulation to respective motor units of a plurality of independent, mutually agonist motor units. A stimulator assembly is configured to provide a stimulation current to each electrode of the plurality of electrodes. The stimulation current is provided such that a sum of respective time-varying moments at the plurality of motor units remains substantially constant and non-zero.
    Type: Application
    Filed: June 14, 2013
    Publication date: January 30, 2014
    Inventors: Lee Fisher, Ronald Triolo, Dustin J. Tyler
  • Publication number: 20130274449
    Abstract: Compositions and methods are provided for treating diseases associated with CD100, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-CD100 monoclonal antibodies have been developed to neutralize CD100.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 17, 2013
    Inventors: Ernest S. SMITH, Terrence Lee Fisher
  • Patent number: 8496938
    Abstract: Compositions and methods are provided for treating diseases associated with CD100, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-CD100 monoclonal antibodies have been developed to neutralize CD100.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: July 30, 2013
    Assignee: Vaccinex, Inc.
    Inventors: Ernest S. Smith, Terrence Lee Fisher
  • Patent number: 8333551
    Abstract: A device operating in an environment includes a fiber optic sensing system having one or more fiber optic sensors disposed in the device and configured to detect one or more parameters related to the device. The parameters may include temperature, strain, pressure, vibration, or combinations thereof.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: December 18, 2012
    Assignee: General Electric Company
    Inventors: Eric John Ruggiero, Kevin Thomas McCarthy, Christopher Edward Wolfe, Hua Xia, Bala Corattiyil, Kenneth Lee Fisher
  • Publication number: 20120270268
    Abstract: Compositions and methods are provided for treating diseases associated with CD100, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-CD100 monoclonal antibodies have been developed to neutralize CD100.
    Type: Application
    Filed: June 14, 2012
    Publication date: October 25, 2012
    Applicant: Vaccinex, Inc.
    Inventors: Ernest S. SMITH, Terrence Lee Fisher
  • Patent number: 8092093
    Abstract: A rotating seal for a gas turbine engine includes: (a) an annular seal body; (b) a sealing component carried by the seal body which is adapted to form one-half of a rotating seal interface; and (c) an impeller carried by the seal body which comprises a plurality of radially-inwardly-extending impeller blades.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: January 10, 2012
    Assignee: General Electric Company
    Inventors: Ning Fang, Ray Harris Kinnaird, Gary Paul Moscarino, Kenneth Lee Fisher, Jonothan Allen Scheetz, Dave William Pugh, Edward William Grace, Duane Howard Anstead, Bala Corattiyil, Prasad Laxman Kane
  • Patent number: 7993425
    Abstract: The present invention provides a free vortex air-oil separator that may be used in systems for separating oil from air oil mixtures. The free vortex air-oil separator comprises a free vortex chamber having a first chamber wall, a second chamber wall located axially aft from the first chamber wall and a rim located in a radially outer region from an axis of rotation, a plurality of vent holes in the rim and a cavity formed by the first and second chamber walls, and the rim, wherein a free vortex is created when there is a flow into the cavity through the plurality of vent holes.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: August 9, 2011
    Assignee: General Electric Company
    Inventors: Bala Corattiyil, Duane Howard Anstead, Mark Eden Zentgraf, Stephen Anthony Wilton, Ramon Themudo, Gary Paul Moscarino, Kenneth Lee Fisher
  • Patent number: 7919594
    Abstract: Compositions and methods are provided for treating diseases associated with CD100, including certain types of cancers, autoimmune diseases, inflammatory diseases including central nervous system (CNS) and peripheral nervous system (PNS) inflammatory diseases, transplant rejections, and invasive angiogenesis. Compositions include anti-CD100 antibodies capable of binding to a soluble human CD100 antigen or a CD100 antigen located on the surface of a human CD100-expressing cell, wherein the antibody has CD100 blocking activity that is achieved by having at least one optimized CDR or FWR engineered within the variable region of the antibody. Compositions also include antigen-binding fragments, variants, and derivatives of the monoclonal antibodies, cell lines producing these antibody compositions, and isolated nucleic acid molecules encoding the amino acid sequences of the antibodies.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: April 5, 2011
    Assignee: Vaccinex, Inc.
    Inventors: Ernest S. Smith, Terrence Lee Fisher, Jr., Maurice Zauderer
  • Publication number: 20100285036
    Abstract: Compositions and methods are provided for treating diseases associated with CD100, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-CD100 monoclonal antibodies have been developed to neutralize CD100.
    Type: Application
    Filed: May 7, 2010
    Publication date: November 11, 2010
    Applicant: Vaccinex, Inc.
    Inventors: Ernest S. Smith, Terrence Lee Fisher
  • Publication number: 20090133961
    Abstract: The present invention provides a free vortex air-oil separator that may be used in systems for separating oil from air oil mixtures. The free vortex air-oil separator comprises a free vortex chamber having a first chamber wall, a second chamber wall located axially aft from the first chamber wall and a rim located in a radially outer region from an axis of rotation, a plurality of vent holes in the rim and a cavity formed by the first and second chamber walls, and the rim, wherein a free vortex is created when there is a flow into the cavity through the plurality of vent holes.
    Type: Application
    Filed: November 28, 2007
    Publication date: May 28, 2009
    Inventors: Bala Corattiyil, Duane Howard Anstead, Mark Eden Zentgraf, Stephen Anthony Wilton, Ramon Themudo, Gary Paul Moscarino, Kenneth Lee Fisher
  • Publication number: 20090087303
    Abstract: A device operating in an environment includes a fiber optic sensing system having one or more fiber optic sensors disposed in the device and configured to detect one or more parameters related to the device. The parameters may include temperature, strain, pressure, vibration, or combinations thereof.
    Type: Application
    Filed: September 28, 2007
    Publication date: April 2, 2009
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Eric John Ruggiero, Kevin Thomas McCarthy, Christopher Edward Wolfe, Hua Xia, Bala Corattiyil, Kenneth Lee Fisher
  • Publication number: 20090034896
    Abstract: A bearing retainer having an inner portion, an outer portion spaced apart from said inner portion, and an intermediate portion connecting the inner portion and the outer portion, such that the inner portion and the outer portion are radially spaced apart and define a space therebetween, and a contact surface on at least one of the inner portion and the outer portion for engaging a component of a bearing assembly disposed in the space.
    Type: Application
    Filed: June 11, 2008
    Publication date: February 5, 2009
    Inventors: Kenneth Lee Fisher, Richard Walker Nicholson, Mark Hopper, Gary Paul Moscarino, Steven Alan Ross, Michael Slusher
  • Publication number: 20080219971
    Abstract: Compositions and methods are provided for treating diseases associated with CD100, including certain types of cancers, autoimmune diseases, inflammatory diseases including central nervous system (CNS) and peripheral nervous system (PNS) inflammatory diseases, transplant rejections, and invasive angiogenesis. Compositions include anti-CD100 antibodies capable of binding to a soluble human CD100 antigen or a CD100 antigen located on the surface of a human CD100-expressing cell, wherein the antibody has CD100 blocking activity that is achieved by having at least one optimized CDR or FWR engineered within the variable region of the antibody. Compositions also include antigen-binding fragments, variants, and derivatives of the monoclonal antibodies, cell lines producing these antibody compositions, and isolated nucleic acid molecules encoding the amino acid sequences of the antibodies.
    Type: Application
    Filed: February 13, 2008
    Publication date: September 11, 2008
    Applicant: Vaccinex, Inc.
    Inventors: Ernest S. Smith, Terrence Lee Fisher, Maurice Zauderer
  • Publication number: 20080114326
    Abstract: Aspects of the present disclosure involve a disposable absorbent article configured to be placed on the body of a wearer to mimic swaddling characteristics. The disposable absorbent article may include a chassis having a tuck flap and two ears or side panels. The two ears extend in opposing lateral directions from a first waist region, and the tuck flap extends in a longitudinal direction from a second waist region. Other chassis embodiments may include two additional ears extending in opposing lateral directions from the second waist region. The chassis is adapted to fit a wearer by wrapping the two ears around a wearer's waist, passing the second waist region between a wearer's legs, and folding and/or tucking the tuck flap over the ears. Embodiments of the chassis may be constructed with manually formed or pre-formed tuck flaps that may also be stretchable.
    Type: Application
    Filed: September 11, 2007
    Publication date: May 15, 2008
    Inventors: Donald Carroll Roe, Carl Louis Bergman, Kimberly Ann Dreier, Constance Lee Fisher, Barry Robert Feist, Mark James Kline
  • Patent number: 7101359
    Abstract: A strong, easy to use tab and slot fastening device suitable for use with disposable absorbent articles. The fastening device preferably includes a tab member and a slot member. The slot member has an inboard portion, an outboard portion and a slot. The inboard portion located laterally inboard of the outboard portion and the slot located between the inboard portion and the outboard portion. The tab member has a length, a proximal edge, a distal edge and a lip portion. The tab portion is passed through the slot of the slot member to engage the fastening device. Once passed through the slot, at least the lip portion of the tab member pivots such that it overlaps the outboard portion of the slot member to prevent the tab member from disengaging from the slot member.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: September 5, 2006
    Assignee: The Procter & Gamble Company
    Inventors: Mark James Kline, Tracey Elaine Beckman, Thomas Henrich, David Joseph Kenneth Goulait, Miguel Alvaro Robles, Constance Lee Fisher
  • Patent number: 7051894
    Abstract: A dispensing container is formed from a toroidal-shaped body having a top surface, a bottom surface, and opposing outer and inner sidewalls defining a hollow interior and a central void. A lid having a tab portion hinged to an actuator portion covers part of the top surface of the body and is dimensioned to cover the aperture. The actuator is depressable to cause the tab portion to pivot away from the aperture, thereby allowing one to dispense the contents present in the container.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: May 30, 2006
    Assignee: Wm. Wrigley Jr. Company
    Inventors: Robert Cregg Barnes, Scott Lee Fisher, Donald Allan Scott, David John Jochem
  • Patent number: 6820417
    Abstract: An exhaust aftertreatment system for use with an internal combustion engine includes at least one leg having a multi-stage NOx adsorber, with each NOx adsorber stage corresponding to a different temperature range of NOx adsorption. In a multi-pass aftertreatment system, a manifold has at least one inlet and a plurality of outlets. A plurality of legs are connected with a respective manifold outlet. Each leg has a NOx adsorber therein. At least one valve is positioned in association with at least one leg for at least partially opening and closing the at least one leg.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: November 23, 2004
    Assignee: Analytical Engineering, Inc.
    Inventors: David F. May, Charles R. Schenk, Louis A. Krempel, H. Lee Fisher, Angela R. May