Patents by Inventor Lee Flippin

Lee Flippin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF
    Publication number: 20080004309
    Abstract: The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Application
    Filed: April 4, 2007
    Publication date: January 3, 2008
    Inventors: Shaojiang DENG, Min Wu, Eric Turtle, Wen-Bin Ho, Michael Arend, Heng Cheng, Lee Flippin
  • CYANOISOQUINOLINE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20070298104
    Abstract: The present invention relates to cyanoisoquinoline compounds suitable for use in treating hypoxia inducible factor-mediated and/or erythropoietin-associated conditions.
    Type: Application
    Filed: January 26, 2007
    Publication date: December 27, 2007
    Inventors: Michael Arend, Lee Flippin, Min Wu, Eric Turtle, Wen-Bin Ho, Shaojiang Deng
  • Novel Nitrogen-Containing Heteroaryl Compounds And Methods of Use Thereof
    Publication number: 20070185159
    Abstract: The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo.
    Type: Application
    Filed: January 19, 2007
    Publication date: August 9, 2007
    Inventors: Michael AREND, Lee Flippin, Volkmar Guenzler-Pukall, Wen-Bin Ho, Eric Turtle, Xiaohui Du
  • Novel nitrogen-containing heteroaryl compounds and methods of use thereof
    Publication number: 20070155784
    Abstract: The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo.
    Type: Application
    Filed: October 13, 2006
    Publication date: July 5, 2007
    Inventors: Michael Arend, Lee Flippin, Volkmar Guenzler-Pukall, Wen-Bin Ho, Eric Turtle, Xiaohui Du
  • Stabilization of hypoxia inducible factor (HIF) alpha
    Publication number: 20060270699
    Abstract: The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
    Type: Application
    Filed: July 28, 2006
    Publication date: November 30, 2006
    Applicant: FibroGen, Inc.
    Inventors: Volkmar Guenzler-Pukall, Thomas Neff, Qingjian Wang, Michael Arend, Lee Flippin, Alex Melekhov
  • Stabilization of hypoxia inducible factor (HIF) alpha
    Publication number: 20060258702
    Abstract: The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
    Type: Application
    Filed: July 28, 2006
    Publication date: November 16, 2006
    Applicant: FibroGen, Inc.
    Inventors: Volkmar Guenzler-Pukall, Thomas Neff, Qingjian Wang, Michael Arend, Lee Flippin, Alex Melekhov
  • Stabilization of hypoxia inducible factor (HIF) alpha
    Publication number: 20060258660
    Abstract: The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
    Type: Application
    Filed: July 28, 2006
    Publication date: November 16, 2006
    Applicant: FibroGen, Inc.
    Inventors: Volkmar Guenzler-Pukall, Thomas Neff, Qingjian Wang, Michael Arend, Lee Flippin, Alex Melekhov
  • Novel nitrogen-containing heteroaryl compounds and methods of use thereof
    Publication number: 20060217416
    Abstract: The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo.
    Type: Application
    Filed: May 26, 2006
    Publication date: September 28, 2006
    Inventors: Michael Arend, Lee Flippin, Volkmar Guenzler-Pukall, Wen-Bin Ho, Eric Turtle, Xiaohui Du
  • Novel thienopyridine compounds, and methods of use thereof
    Publication number: 20060199836
    Abstract: The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Application
    Filed: March 2, 2006
    Publication date: September 7, 2006
    Inventors: Eric Turtle, Lee Flippin, Michael Arend, Heng Cheng
  • Methods of increasing endogenous erythropoietin (EPO)
    Publication number: 20060183695
    Abstract: The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 17, 2006
    Applicant: FibroGen, Inc.
    Inventors: Stephen Klaus, Al Lin, Thomas Neff, Qingjian Wang, Volkmar Guenzler-Pukall, Michael Arend, Lee Flippin, Alex Melekhov
  • Methods of increasing endogenous erythropoietin (EPO)
    Publication number: 20060178317
    Abstract: The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 10, 2006
    Applicant: FibroGen, Inc.
    Inventors: Stephen Klaus, Al Lin, Thomas Neff, Qingjian Wang, Volkmar Guenzler-Pukall, Michael Arend, Lee Flippin, Alex Melekhov
  • Methods of increasing endogenous erythropoietin (EPO)
    Publication number: 20060178316
    Abstract: The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 10, 2006
    Applicant: FibroGen, Inc.
    Inventors: Stephen Klaus, Al Lin, Thomas Neff, Qingjian Wang, Volkmar Guenzler-Pukall, Michael Arend, Lee Flippin, Alex Melekhov