Abstract: A guide for an esophageal echo probe includes a bite block with a collar about one end thereof to seat about the patient's mouth and a sleeve of low friction, flexible, form-retaining material having a generally arcuate configuration and dimensioned and configured to extend from the patient's mouth through the ovopharynx and into the esophagus. A secondary guide extends along the length of the bite block and sleeve and provides a passage seating an orogastric tube to lead the sleeve through the ovopharynx and into the esophagus. The passage through the bite block and sleeve is dimensioned to slidably receive and guide a transesophageal echo probe for placement in the patient's body.