Abstract: A diagnostic device, process, system and software arrangement are provided for ascertaining particular information (e.g., medical dosage recommendation and/or therapeutic recommendation) related to a patient. In particular, a diagnostic device can receive previously-stored data associated with the patient from a remote device. Then, a test to ascertain the particular information based on the received previously-stored data can be performed on a biological property (e.g., a biological sample). The particular information may include a level of at least one measurement for the biological property, which may be a compound provided in the sample, with the sample containing a bodily fluid of the patient A web access processing arrangement can also be made available such that access to the respective patient associated with the particular information and a further user (e.g., the patient's physician, nurse, relatives etc.

Abstract: An apparatus for the measurement of intracranial pressure in an area proximate to the jugular bulb from a minimally invasive insertion point exterior to the cranial cavity, comprising a narrow diameter intravascular catheter (20) and a conventional guidewire (32, not shown), a first proximal balloon (22) and a second distal balloon (24), an aperture (26) in the distal portion of the catheter (20) for accommodating a sensor (28) or emitter and an aperture (30) in the distal end (31) for accommodating the guidewire (32). An inflation/deflation mechanism (37) is connected to the catheter via an aperture (34) in the external wall of the catheter (20).

Abstract: A bolus containing optical and MRI contrast agents is administered to a patient for determining quantitative perfusion indices from perfusion weighted magnetic resonance imaging analysis (PWI). The optical contrast agent time-concentration data, which can be obtained non-invasively, is used to define an arterial input function. The MRI contrast agent time concentration can be non-invasively determined using MRI to define a tissue function. An MRI time-signal curve can be determined by deconvolving the arterial and tissue functions. In one embodiment, SVD is used to determine a residue function from which a flow map can be computed.

Abstract: A bolus containing optical and MRI contrast agents is administered to a patient for determining quantitative perfusion indices from perfusion weighted magnetic resonance imaging analysis (PWI). The optical contrast agent time-concentration data, which can be obtained non-invasively, is used to define an arterial input function. The MRI contrast agent time concentration can be non-invasively determined using MRI to define a tissue function. An MRI time-signal curve can be determined by deconvolving the arterial and tissue functions. In one embodiment, SVD is used to determine a residue function from which a flow map can be computed.