Patents by Inventor Lee Hedemyr

Lee Hedemyr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chelator and use thereof
    Patent number: 10662261
    Abstract: The present invention relates to dimeric pentadentate chelators with exceptionally strong binding of metal ions, for detection, immobilization and purification of biomolecules. Dimeric chelators offer a cooperativity of binding of two adjacent immobilized metal ions simultaneously to a histidine-tagged biomolecule, which gives advantageous properties regarding strength of binding compared to a corresponding monomer chelator. In addition, a dimer increases the selectivity (ease of separation) against non-tagged biomolecules with low metal-ion affinity.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: May 26, 2020
    Assignee: GE Healthcare BioProcess R&D AB
    Inventors: Mattias Algotsson, Lars C. Andersson, Eggert Brekkan, Lee Hedemyr, Jean-Luc Maloisel, Ronnie Palmgren
  • Novel Chelator and Use Thereof
    Publication number: 20180223003
    Abstract: The present invention relates to dimeric pentadentate chelators with exceptionally strong binding of metal ions, for detection, immobilization and purification of biomolecules. Dimeric chelators offer a cooperativity of binding of two adjacent immobilized metal ions simultaneously to a histidine-tagged biomolecule, which gives advantageous properties regarding strength of binding compared to a corresponding monomer chelator. In addition, a dimer increases the selectivity (ease of separation) against non-tagged biomolecules with low metal-ion affinity.
    Type: Application
    Filed: March 27, 2018
    Publication date: August 9, 2018
    Inventors: Mattias Algotsson, Lars C. Andersson, Eggert Brekkan, Lee Hedemyr, Jean-Luc Maloisel, Ronnie Palmgren
  • Chelator and use thereof
    Patent number: 9944722
    Abstract: The present invention relates to dimeric pentadentate chelators with exceptionally strong binding of metal ions, for detection, immobilization and purification of biomolecules. Dimeric chelators offer a cooperativity of binding of two adjacent immobilized metal ions simultaneously to a histidine-tagged biomolecule, which gives advantageous properties regarding strength of binding compared to a corresponding monomer chelator. In addition, a dimer increases the selectivity (ease of separation) against non-tagged biomolecules with low metal-ion affinity.
    Type: Grant
    Filed: May 30, 2011
    Date of Patent: April 17, 2018
    Assignee: GE Healthcare Bioprocess R&D AB
    Inventors: Mattias Algotsson, Lars C. Andersson, Eggert Brekkan, Lee Hedemyr, Jean-Luc Maloisel, Ronnie Palmgren
  • NOVEL CHELATOR AND USE THEREOF
    Publication number: 20130072638
    Abstract: The present invention relates to dimeric pentadentate chelators with exceptionally strong binding of metal ions, for detection, immobilization and purification of biomolecules. Dimeric chelators offer a cooperativity of binding of two adjacent immobilized metal ions simultaneously to a histidine-tagged biomolecule, which gives advantageous properties regarding strength of binding compared to a corresponding monomer chelator. In addition, a dimer increases the selectivity (ease of separation) against non-tagged biomolecules with low metal-ion affinity.
    Type: Application
    Filed: May 30, 2011
    Publication date: March 21, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Mattias Algotsson, Lars C. Andersson, Eggert Brekkan, Lee Hedemyr, Jean-Luc Maloisel, Ronnie Palmgren