Abstract: Disclosed herein is a buoyant structure for offshore deployment. The buoyant structure comprises a first deck having a first channel through the first deck; a second deck having a second channel through the second deck, wherein the first deck and second deck are coupled to each other and arranged spaced apart from each other; and a plurality of floatable substructures coupled to and around at least one of the first deck and the second deck, the plurality of floatable substructures arranged spaced apart from one another, wherein the first channel and the second channel are aligned to receive at least a portion of a tower of a wind turbine.

Abstract: Disclosed herein is a method for determining whether a subject is suffering from, or is at risk of developing breast cancer, wherein the method comprises detecting differential expression levels of at least two or more miRNA markers from a biological sample. Also disclosed herein is a method of determining whether a subject is suffering from, or is at risk of developing, breast cancer based on miRNA expression.

Abstract: The disclosure provides compositions and methods that combine the benefits of different genetic analysis methods by performing simultaneous genetic analysis on a single pool of different libraries that were generated for different approaches, such as a combined library comprising a LPWG library and a target-enriched library.

Abstract: A semiconductor device includes a conductive can include a flat portion and at least one peripheral rim portion extending from an edge of the flat portion, a semiconductor die comprising a first main face and a second main face opposite to the first main face, a first contact pad disposed on the first main face and a second contact pad disposed on the second main face, wherein the first contact pad is electrically connected to the flat portion of the can, an electrical interconnector connected with the second contact pad, and an encapsulant disposed under the semiconductor die so as to surround the electrical interconnector, wherein an external surface of the electrical interconnector is recessed from an external surface of the encapsulant.

Abstract: This technology relates to a method of treating breast cancer in a subject and a method of determining whether a breast lesion in a subject is malignant or benign using miRNA panels.

Abstract: Disclosed herein is a buoyant structure for offshore deployment. The buoyant structure comprises a first deck having a first channel through the first deck; a second deck having a second channel through the second deck, wherein the first deck and second deck are coupled to each other and arranged spaced apart from each other; and a plurality of floatable substructures coupled to and around at least one of the first deck and the second deck, the plurality of floatable substructures arranged spaced apart from one another, wherein the first channel and the second channel are aligned to receive at least a portion of a tower of a wind turbine.

Abstract: The present invention includes compositions and methods useful for the detection of a mutational change. SNP, translocation, inversion, deletion, change in copy number, or other genetic variation within a sample of cellular genomic DNA or cell-free DNA (cfDNA). In some embodiments, the compositions and methods of the present invention provide an extremely high level of resolution that is particularly useful in detecting copy number variations in a small fraction of the total cfDNA from a biological sample (e.g., blood).

Abstract: The invention provides a method for efficient DNA library construction and targeted genetic analyses of the libraries.

Abstract: The present subject matter relates to techniques of controlling a position of a microphone coupled to a headset. In an example implementation of present subject matter, the position of the microphone coupled to the headset is changed between a first position and a second position, depending upon a signal received by the headset.

Abstract: An example of an apparatus including a rendering engine to render an image to a display. The image includes a pointer. The apparatus further includes an input interface associated with the pointer to receive movement data. The apparatus also includes an analysis engine to process the movement data to determine whether the movement data represents a command to locate the pointer on the display. In addition, the apparatus includes an applet engine to execute an applet upon receiving the command The applet generates a pop-up window to provide a location of the pointer.

Abstract: The present invention includes compositions and methods useful for the detection of a mutational change, SNP, translocation, inversion, deletion, change in copy number, or other genetic variation within a sample of cellular genomic DNA or cell-free DNA (cfDNA). In some embodiments, the compositions and methods of the present invention provide an extremely high level of resolution that is particularly useful in detecting copy number variations in a small fraction of the total cfDNA from a biological sample (e.g., blood).

Abstract: In an example implementation according to aspects of the present disclosure, a method may include determining whether a user profile associated with a user of a computing device is available for a human interface device (HID) of the computing device, and, upon determining that the user profile is available, adjusting a parameter of the HID according to a setting found in the user profile.

Abstract: The present subject matter relates to techniques of controlling a position of a microphone coupled to a headset. In an example implementation of present subject matter, the position of the microphone coupled to the headset is changed between a first position and a second position, depending upon a signal received by the headset.

Abstract: A semiconductor device includes a conductive can include a flat portion and at least one peripheral rim portion extending from an edge of the flat portion, a semiconductor die comprising a first main face and a second main face opposite to the first main face, a first contact pad disposed on the first main face and a second contact pad disposed on the second main face, wherein the first contact pad is electrically connected to the flat portion of the can, an electrical interconnector connected with the second contact pad, and an encapsulant disposed under the semiconductor die so as to surround the electrical interconnector, wherein an external surface of the electrical interconnector is recessed from an external surface of the encapsulant.

Abstract: A key assembly for a keyboard may include a key cap that includes a touch sensor that is communicatively coupled to a control device. When the touch sensor senses a touch event, the touch sensor may send a touch signal to the control device, and when the touch sensor senses an absence of touch, the touch sensor may send a control signal to the control device. The key assembly may further include a switch that is communicatively coupled to the control device and that is movable between a pressed position and an un-pressed position. When the switch is in the pressed position, the switch may send a closed signal to the control device, and when the switch is in the un-pressed position, the switch may send an open signal to the control device. Various other apparatuses, systems, and methods are also disclosed.

Abstract: The instant disclosure features single-stranded RNA molecules comprising one or more internal, non-nucleotide spacers. A non-nucleotide spacer covalently links nucleotide portions of the molecule. The single-stranded RNA molecules function as guide or antisense strands that are capable of inhibiting gene expression via an RNA interference mechanism and, thus, represent single-stranded RNAi agents. The single-stranded RNAi molecules can be used in methods for a variety of therapeutic, diagnostic, target validation, genomic discovery, genetic engineering, and pharmacogenomic applications.

Abstract: A package includes an electronic chip having a pad. The pad is at least partially covered with adhesion enhancing structures. The pad and the adhesion enhancing structures have at least aluminium in common.

Abstract: This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.

Abstract: A key assembly for a keyboard may include a key cap that includes a touch sensor that is communicatively coupled to a control device. When the touch sensor senses a touch event, the touch sensor may send a touch signal to the control device, and when the touch sensor senses an absence of touch, the touch sensor may send a control signal to the control device. The key assembly may further include a switch that is communicatively coupled to the control device and that is movable between a pressed position and an un-pressed position. When the switch is in the pressed position, the switch may send a closed signal to the control device, and when the switch is in the un-pressed position, the switch may send an open signal to the control device. Various other apparatuses, systems, and methods are also disclosed.

Abstract: A key assembly for a keyboard may include a key cap that includes a touch sensor that is communicatively coupled to a control device. When the touch sensor senses a touch event, the touch sensor may send a touch signal to the control device, and when the touch sensor senses an absence of touch, the touch sensor may send a control signal to the control device. The key assembly may further include a switch that is communicatively coupled to the control device and that is movable between a pressed position and an un-pressed position. When the switch is in the pressed position, the switch may send a closed signal to the control device, and when the switch is in the un-pressed position, the switch may send an open signal to the control device. Various other apparatuses, systems, and methods are also disclosed.