Patents by Inventor Lee Noll

Lee Noll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • En vivo generated tissue system
    Patent number: 8778330
    Abstract: The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: July 15, 2014
    Assignee: Aastrom Biosciences, Inc.
    Inventors: Lee Noll, Brian Hampson, Kristin Goltry, Samantha Snabes
  • EN VIVO GENERATED TISSUE SYSTEM
    Publication number: 20130295057
    Abstract: The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
    Type: Application
    Filed: March 11, 2013
    Publication date: November 7, 2013
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Lee Noll, Brian Hampson, Kristin Goltry, Samantha Snabes
  • In Vitro Tumor Metastasis Model
    Publication number: 20130196349
    Abstract: This invention provides a system and methods for modeling tumor metastasis in vitro where primary tumor tissue is cultivated in an orientation and an environment such that the natural composition, three-dimensional organization, and environmental conditions of the tumor can be adjusted. The invention further provides mechanism for inducing tumors to undergo metastatic processes resulting in production of tumor progenitor or stem cells that can be collected, characterized, or used to induce tumors in normal tissue constructs in vitro.
    Type: Application
    Filed: August 2, 2012
    Publication date: August 1, 2013
    Applicants: REALBIO TECHNOLOGY, INC., ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: George A. Martin, Lee A. Noll, William P. Pfund
  • Ex vivo generated tissue system
    Patent number: 8394632
    Abstract: The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: March 12, 2013
    Assignee: Aastrom Biosciences, Inc.
    Inventors: Lee Noll, Brian Hampson, Kristin Goltry, Samantha Snabes
  • Ex vivo generated tissue system
    Patent number: 7682822
    Abstract: The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: March 23, 2010
    Assignee: Aastrom Biosciences, Inc.
    Inventors: Lee Noll, Brian Hampson, Kristin Goltry, Samantha Snabes
  • EX VIVO GENERATED TISSUE SYSTEM
    Publication number: 20100055792
    Abstract: The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
    Type: Application
    Filed: November 10, 2009
    Publication date: March 4, 2010
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Lee NOLL, Brian Hampson, Kristin Goltry, Samantha Snabes
  • Ex vivo generated tissue system
    Publication number: 20070231305
    Abstract: The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
    Type: Application
    Filed: March 31, 2006
    Publication date: October 4, 2007
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Lee Noll, Brian Hampson, Kristin Goltry, Samantha Snabes
  • Cell culture using a monolithic support
    Patent number: 4514499
    Abstract: A novel immobilized cell composite used in a novel apparatus/method for cell culture. The composite comprises:(a) a high surface area monolithic support having a multiplicity of mutually parallel channels passing therethrough, the channels having walls formed of a medium-insoluble, non-toxic, composition and the support having at least about 20 channels per square inch of cross-sectional area; and(b) a population of plant or animal tissue cells anchored to the porous channel walls.
    Type: Grant
    Filed: February 4, 1983
    Date of Patent: April 30, 1985
    Assignee: Corning Glass Works
    Inventor: Lee A. Noll