Patents by Inventor Lee P Lim

Lee P Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High efficiency construction of DNA libraries
    Patent number: 11339391
    Abstract: The invention provides a method for efficient DNA library construction and targeted genetic analyses of the libraries.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: May 24, 2022
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher K. Raymond, Lee P. Lim
  • METHODS FOR TARGETED GENOMIC ANALYSIS
    Publication number: 20210198658
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Application
    Filed: January 5, 2021
    Publication date: July 1, 2021
    Inventors: Christopher K. RAYMOND, Christopher D. ARMOUR, Lee P. LIM
  • Methods for targeted genomic analysis
    Patent number: 10907149
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: February 2, 2021
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher K. Raymond, Christopher D. Armour, Lee P. Lim
  • HIGH EFFICIENCY CONSTRUCTION OF DNA LIBRARIES
    Publication number: 20180245072
    Abstract: The invention provides a method for efficient DNA library construction and targeted genetic analyses of the libraries.
    Type: Application
    Filed: April 27, 2018
    Publication date: August 30, 2018
    Inventors: Christopher K. RAYMOND, Lee P. LIM
  • METHODS FOR QUANTITATIVE GENETIC ANALYSIS OF CELL FREE DNA
    Publication number: 20180179578
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provides methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Application
    Filed: October 9, 2017
    Publication date: June 28, 2018
    Inventors: Christopher K. RAYMOND, Lee P. LIM, Christopher D. ARMOUR
  • METHODS FOR TARGETED GENOMIC ANALYSIS
    Publication number: 20180142234
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Application
    Filed: January 17, 2018
    Publication date: May 24, 2018
    Inventors: Christopher K. RAYMOND, Christopher D. ARMOUR, Lee P. LIM
  • Methods for targeted genomic analysis
    Patent number: 9932576
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: April 3, 2018
    Assignee: RESOLUTION BIOSCIENCE, INC.
    Inventors: Christopher K. Raymond, Christopher D. Armour, Lee P. Lim
  • METHODS FOR QUANTITATIVE GENETIC ANALYSIS OF CELL FREE DNA
    Publication number: 20160053301
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provides methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 25, 2016
    Inventors: CHRISTOPHER K. RAYMOND, LEE P. LIM, CHRISTOPHER D. ARMOUR
  • METHODS FOR TARGETED GENOMIC ANALYSIS
    Publication number: 20140274731
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Application
    Filed: December 10, 2013
    Publication date: September 18, 2014
    Applicant: CLEARFORK BIOSCIENCE, INC.
    Inventors: Christopher K. RAYMOND, Christopher D. ARMOUR, Lee P. LIM
  • Methods of using MIR34 as a biomarker for TP53 functional status
    Patent number: 8399248
    Abstract: In one aspect, the invention generally relates to use of miR-34 as a biomarker to estimate TP53 function in a cell. In another aspect, the invention generally relates to multiple uses of miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: March 19, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michele A. Cleary, Aimee L. Jackson, Peter S. Linsley, Julja Burchard, Lee P. Lim, Jill F. Magnus, Lin He, Xingyue He, Scott W. Lowe, Gregory J. Hannon
  • Compositions comprising MIR34 therapeutic agents for treating cancer
    Patent number: 8378088
    Abstract: In one aspect, the invention generally relates to compositions comprising miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: February 19, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Michele A Cleary, Aimee L Jackson, Peter S Linsley, Julja Burchard, Lee P Lim, Jill F Magnus
  • METHODS OF USING MIR34 AS A BIOMARKER FOR TP53 FUNCTIONAL STATUS
    Publication number: 20110105583
    Abstract: In one aspect, the invention generally relates to use of miR-34 as a biomarker to estimate TP53 function in a cell. In another aspect, the invention generally relates to multiple uses of miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Application
    Filed: May 5, 2008
    Publication date: May 5, 2011
    Applicants: MERCK & CO., INC., COLD SPRING HARBOR LABORATORY
    Inventors: Michele A. Cleary, Aimee L. Jackson, Peter S. Linsley, Julja Burchard, Lee P. Lim, Jill F. Magnus, Lin He, Xingyue He, Scott W. Lowe, Gregory J. Hannon
  • COMPOSITIONS COMPRISING MIR34 THERAPEUTIC AGENTS FOR TREATING CANCER
    Publication number: 20100227909
    Abstract: In one aspect, the invention generally relates to compositions comprising miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.
    Type: Application
    Filed: May 5, 2008
    Publication date: September 9, 2010
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michele A. Cleary, Aimee L. Jackson, Peter S. Linsley, Julja Burchard, Lee P. Lim, Jill F. Magnus