Abstract: The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.

Abstract: A continuous process for making a pigment dispersion includes continuously feeding a pigment into a feed section of a screw extruder at a controlled rate, continuously feeding a surfactant into the feed section of the screw extruder at a controlled rate, continuously feeding water downstream of the feed section to emulsify the pigment and the surfactant, forming a water-in-pigment dispersion, continuously feeding additional water downstream of the previously fed water to cause a phase inversion of the water-in-pigment dispersion, forming a pigment-in-water dispersion, continuously homogenizing the pigment-in-water dispersion in the screw extruder to create a homogenous aqueous pigment dispersion and collecting the homogenous aqueous pigment dispersion from an exit section of the screw extruder.

Abstract: A continuous process for making a pigment dispersion includes continuously feeding a pigment into a feed section of a screw extruder at a controlled rate, continuously feeding a surfactant into the feed section of the screw extruder at a controlled rate, continuously feeding water downstream of the feed section to emulsify the pigment and the surfactant, forming a water-in-pigment dispersion, continuously feeding additional water downstream of the previously fed water to cause a phase inversion of the water-in-pigment dispersion, forming a pigment-in-water dispersion, continuously homogenizing the pigment-in-water dispersion in the screw extruder to create a homogenous aqueous pigment dispersion and collecting the homogenous aqueous pigment dispersion from an exit section of the screw extruder.

Abstract: The cephalosporin compound of formula (I) is disclosed, which exhibits antibiotic activity against Gram-negative (e.g., Pseudomonas aeruginosa) and Gram-positive (e.g., methicillin-resistant Staphylococcus aureus) bacteria. Methods of manufacturing the compound of formula (I), and uses of the compound in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.

Abstract: The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.

Abstract: The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.

Abstract: The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.

Abstract: Cotton harvester frame structure includes main structural members elevated to approximately cab floor level and extending horizontally rearwardly in a planar fashion over the engine compartment and the rear axle. The structural members attach to the central portion of the rear axle to provide added clearance for larger wheels and tires. The single elevated plane of the main frame structure provides simplified attachment of a power module including a transversely mounted engine. Access areas under the main structural members are of sufficient minimum width and height to allow an operator or an assembler to stand fairly erect while accessing most areas of the power module and a harvester fan.

Abstract: Cotton harvester frame structure includes main structural members elevated to approximately cab floor level and extending horizontally rearwardly in a planar fashion over the engine compartment and the rear axle. The structural members attach to the central portion of the rear axle to provide added clearance for larger wheels and tires. The single elevated plane of the main frame structure provides simplified attachment of a power module including a transversely mounted engine. Access areas under the main structural members are of sufficient minimum width and height to allow an operator or an assembler to stand fairly erect while accessing most areas of the power module and a harvester fan.

Abstract: A chassis-mounted round baler particularly useful with an on-board cotton module building system includes a bale release gate frame section connected to a forward frame section by a four bar linkage to define a gate path that allows the folding of the baler into both field transport and shipping configurations while maintaining desirable operating, transport and shipping heights. The gate linkage incorporates a self latching feature wherein a small vertical movement of the gate as the gate cylinders are operated releases a gate latch member from a forward frame member during gate opening and reengages the gate latch with the forward frame member during closing. The gate interacts with the bale handler to provide a stop for the baler gate when the baler gate is placed into a cradle on the handler.

Abstract: A hood receives a stream of material including a mix of cotton, air and debris from an air delivery system on a cotton harvester. A forward deflector directs the mixture towards the rear of an accumulator. The deflected mixture passes under finger grates which retains cotton but allows some of the air and light trash to pass through out of the stream. A curved rear deflector forces the remaining mix downwardly towards the accumulator and prevents build-up on receptacle walls. Air and light debris change direction abruptly at the bottom of the rear deflector and exit through an inlet area and upwardly directed path at the back of the deflector. The momentum of the heavier cotton prevents cotton from making the tight turn around the bottom of the deflector and directs the cotton towards the receptacle or accumulator. The inlet area can be adjusted or closed completely to prevent cotton loss in certain conditions.

Abstract: A plastics moulded part with a soft-feel surface 12 has a layer of soft material 26,28,30 moulded on the surface of the part. The edges of the soft material are protected and hidden by a rib 44 which is part of the moulded part, which extends in a plane which runs generally parallel to the contour of the part in the region of the rib 44 and which is substantially coplanar with the surface of the part not covered by soft material. The soft material is placed in the mould prior to plastics injection. During injection, the soft material is compressed against the outer mould wall. On ejection from the mould, the soft material recovers and expands so that its outer surface 31 is flush with the outer surface of the rib 44.

Abstract: Lower spiked rollers in the bottom of a cotton accumulator are inclined in the downstream direction towards an opening and rotate in the same direction to pull cotton down to the opening. An upper spiked roller located above the opening and above the last of the lower spiked rollers is only partially exposed to the cotton in the accumulator. The upper roller meters the cotton and tears apart clumps. An opening above the upper roller defines an upper discharge opening over the main discharge opening. When in a non-rotating condition, the spiked rollers act as a floor for the accumulator and prevent egress of the cotton through the openings.

Abstract: A duct support and transition structure for the air system of a cotton harvester includes a plurality of upright telescoping duct sections connected to a vertically adjustable support tube extending transversely between the sections providing lateral support for the ducts. Hydraulically operated slide structure connected to the support tube moves the sections vertically between operating and transport positions and eliminates duct binding problems. A telescoping harvester basket supports forwardly extending hood structure. The hood structure opens downwardly towards the upper ducts and includes grates for exhausting air and debris. The ends of the ducts open upwardly rather than rearwardly into the hood structure. The basket can move to and from the dump position without interference from the ducts, and the hood structure reduces cotton loss without need for side shields.

Abstract: A duct support and transition structure for the air system of a cotton harvester includes a plurality of upright telescoping duct sections connected to a vertically adjustable support tube extending transversely between the sections providing lateral support for the ducts. Hydraulically operated slide structure connected to the support tube moves the sections vertically between operating and transport positions and eliminates duct binding problems. A telescoping harvester basket supports forwardly extending hood structure. The hood structure opens downwardly towards the upper ducts and includes grates for exhausting air and debris. The ends of the ducts open upwardly rather than rearwardly into the hood structure. The basket can move to and from the dump position without interference from the ducts, and the hood structure reduces cotton loss without need for side shields.