Abstract: A wireless process variable transmitter for use in an industrial process includes a process variable sensor configured to sense a process variable of the industrial process and provide a process variable sensor output. A battery power source includes a plurality of battery power banks each having a primary cell battery, a low voltage cut-off circuit electrically connected to the primary cell battery which provides an electrical connection to the primary cell battery while a voltage of the primary cell battery is above a threshold, and an ideal diode having an input electrically connected to the primary cell battery through the low voltage cut-off and providing a power bank output. A power sharing node has an input connected to the battery power bank output of each of the plurality of battery power banks and having a shared power output which provides power to circuitry of the wireless process variable transmitter.

Abstract: Cargo assemblages including a pallet, a load of packages arranged in one or more layers. and a support layer, in which the support layer is sized and positioned within the cargo assemblage to support and/or stabilize the cargo, thereby providing improved pallet efficiency, improved shipping efficiency, and/or improved stability.

Abstract: Described herein are methods and compositions for the treatment of ocular conditions and for the improvement of vision parameters using pharmaceutically acceptable ophthalmic pilocarpine formulations. A nonlimiting example of an ocular condition that may be treated with the methods and compositions disclosed herein is presbyopia.

Abstract: The present invention relates to Shiga toxin effector polypeptides with reduced antigenic and/or immunogenic potential. Immunogenicity can be a limitation for the repeated administration to mammals of proteins and polypeptides derived from Shiga toxins. The Shiga toxin effector polypeptides of the present invention have uses as components of therapeutics, diagnostics, and immunization materials. The cytotoxic proteins of the present invention have uses for selective killing of specific cell types and as therapeutics for the treatment of a variety of diseases, including cancers, immune disorders, and microbial infections. The proteins of the present invention also have uses for detecting specific cell types, collecting diagnostic information, and monitoring the treatment of a variety of diseases, such as, e.g., cancers, immune disorders, and microbial infections.

Abstract: Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound contact layer, an absorbent layer over the wound contact layer, the absorbent layer comprising one or more apertures, a cover layer configured to cover and form a seal over the wound contact layer and the absorbent layer, and an electronics assembly comprising a negative pressure source. A portion of the cover layer overlying the one or more apertures in the absorbent layer can be configured to be compressed within the aperture in the absorbent layer when negative pressure is applied to the wound dressing apparatus. The compressed cover layer can indicate a level of negative pressure below the cover layer. In some embodiments, the wound dressing apparatus can comprise an indicator material layer and a cover layer configured to cover and form a seal over the wound contact layer and the indicator material layer.

Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, R2 and R3 are as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. A wound dressing apparatus can comprises a wound contact layer, at least one absorbent layer, an electronics unit comprising a negative pressure source unit, and a cover layer. The electronics unit can comprise a plurality of sensors positioned on a printed circuit board and an inlet protection mechanism of the negative pressure source unit comprises a first recess in fluid communication with a first sensor and the outlet or exhaust mechanism negative pressure source unit comprises a second recess in fluid communication with a second sensor.

Abstract: Cargo assemblages including a pallet, a load of packages arranged in one or more layers, and a support layer, in which the support layer is sized and positioned within the cargo assemblage to support and/or stabilize the cargo, thereby providing improved pallet efficiency, improved shipping efficiency, and/or improved stability.

Abstract: A product delivery system includes a product transport vehicle having at least a plurality of tank compartments, internal valves, control valves, fluid property sensors, temperature sensors, overfill sensors, pressure sensors, a system controller, and a memory module. The product delivery system may be operable to communicatively connect with the loading system at a loading station, a fleet management system, or a cloud system to obtain information, such as the amount of liquid product to be loaded into a tank compartment. The product delivery system may be operable to compare the volumes of the tank compartments with the amounts of liquid product to be loaded at a loading station and maintain the internal valve or control valve in a locked state or transition the internal valve or control valve to an unlocked state based on the comparison. Other comparisons based on liquid type or distribution tank volume can also be made.

Abstract: The present invention relates to Shiga toxin effector polypeptides with reduced antigenic and/or immunogenic potential. Immunogenicity can be a limitation for the repeated administration to mammals of proteins and polypeptides derived from Shiga toxins. The Shiga toxin effector polypeptides of the present invention have uses as components of therapeutics, diagnostics, and immunization materials. The cytotoxic proteins of the present invention have uses for selective killing of specific cell types and as therapeutics for the treatment of a variety of diseases, including cancers, immune disorders, and microbial infections. The proteins of the present invention also have uses for detecting specific cell types, collecting diagnostic information, and monitoring the treatment of a variety of diseases, such as, e.g., cancers, immune disorders, and microbial infections.

Abstract: Disclosed are methods and systems that can maintain patient privacy in a video stream of a medical facility by obfuscating all patient identity information such that the patient's identity and medical information is protected. In addition, the system and methods disclosed herein can limit the change in the perspective of the camera based on a defined privacy zone in the medical facility such that the privacy zone is not in the field of view of the camera.

Abstract: An ultrasonic transducer probe comprises an array transducer and a microbeamformer ASIC (46a, 46b) containing transmit amplifiers and receive circuitry for operation of the array transducer. For higher power operation, the drive current of the amplifiers is increased, rather than the transmit voltage. The elements of the array present a low impedance to the transmit amplifiers for increased drive current by their construction of thin layers (12) of piezoelectric material which are electrically coupled in parallel to an amplifier while being mechanically coupled in series for ultrasound transmission.

Abstract: A ballast dispenser system and method for flight vehicles, such as high altitude lighter than air vehicles. The system passively retains ballast without power and deploys ballast in response to applying power. An electro-permanent magnet passively retains ballast within the dispenser. Application of power to a coil produces an opposing magnetic field that reduces the overall strength of a net magnetic field acting on the ballast. Lateral positional control of the electro-permanent magnet provides calibration and control of the retaining magnetic field strength. A collapsible silo may hold ballast prior to dispensing ballast and collapse upon landing for minimizing damage.

Abstract: The invention is directed to an ultrasound probe (1) configured to be operatively coupled to a cable (10), the cable (10) comprising a plurality of lanes adapted to carry signals between the ultrasound probe (1) and a data processing unit, which is adapted to process the signals, in particular to beamform the signals and to reconstruct ultrasound images of an imaging region. The ultrasonic probe (1) comprises a transducer head comprising a plurality of transducer elements, which are adapted to insonify the imaging region according to an insonification scheme and to receive ultrasound signals, and a controller adapted to, responsive to the information of a faulty lane from a fault detection module adapted to detect integrity of each of the plurality of lanes, redistribute and/or reconfigure the signals carried by the faulty lane onto one or more of the non-faulty lanes.

Abstract: Ultrasound imaging systems are provided. An ultrasound system according to some embodiments includes a console configured to selectively communicate with a first ultrasound imaging device and a second ultrasound imaging device. The console includes a housing, a computing device disposed within the housing, and a connector receptacle assembly coupled to the housing. The connector receptacle assembly includes a first connector bank including a first plurality of electrical connections; and a second connector bank including a second plurality of electrical connections. The connector receptacle assembly is selectively matable to a first connector of the first ultrasound imaging device via only the first connector bank and to a second connector of the second ultrasound imaging device via the first and second connector banks.

Abstract: A new and distinct variety of apple tree rootstock Malus domestica x Malus robusta hybrid ‘G.257’ is described. The new variety is a semi-dwarfing rootstock that is resistant to fire blight (Erwinia amylovora) and crown rot (Phytophthora cactorum) and tolerant to the replant disease complex. The ‘G.257’ rootstock is useful in that it can be propagated clonally and used as a rootstock or root system for apple trees as well as for interstems of apple trees.

Abstract: A new and distinct variety of apple tree rootstock Malus hybrid ‘G.484’ is described herein. The new variety is a dwarfing, precocious and productive rootstock that is resistant to fire blight (Erwinia amylovora) and crown rot (Phytophthora cactorum). The ‘G.484’ rootstock is useful in that it can be propagated clonally and used as a rootstock or root system for apple trees as well as for interstems of apple trees.

Abstract: A new and distinct variety of apple tree rootstock Malus domestica x Malus robusta hybrid ‘G.66’ is described herein. The new variety is a productive, yield efficient, semi-dwarfing rootstock that is resistant to fire blight (Erwinia amylovora) and crown rot (Phytophthora cactorum). The ‘G.66’ rootstock is useful in that it can be propagated clonally and used as a rootstock or root system for apple trees as well as for interstems of apple trees.

Abstract: A new and distinct cultivar of Styrax plant named ‘RNI-RIXRED’ is disclosed, characterized by dark, glossy foliage with emerging new growth colored bronze. Flowers bloom twice per year, in spring and again in fall. Petite, white flowers have a shiny quality. The new variety is a Styrax, normally used for outdoor ornamental purposes.