Patents by Inventor Lee Shapiro

Lee Shapiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959127
    Abstract: Temperature sensitive transcriptional bioswitches and related genetic circuits and in particular bandpass and/or multiplex genetic circuits, vectors, cells, compositions methods and systems are described.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: April 16, 2024
    Assignee: California Institute of Technology
    Inventors: Mikhail G. Shapiro, Dan Piraner, Mohamad H. Abedi, Brittany Moser, Audrey Lee-Gosselin
  • Publication number: 20190102794
    Abstract: Systems and methods are described herein for monitoring consumer behavior on an individual level across a plurality of consumer data providers. The systems and methods described herein can receive consumer behavior data for an individual consumer. The consumer behavior data can be generated based on advertisements and digital advertisements assets relative to the individual consumer.
    Type: Application
    Filed: October 2, 2017
    Publication date: April 4, 2019
    Inventors: Jillian Lee Shapiro, James Frederick Caruso, Jona Mici
  • Publication number: 20190102795
    Abstract: Systems and methods are described herein for monitoring consumer behavior on an individual level across a plurality of consumer data providers. The systems and methods described herein can receive consumer behavior data for an individual consumer. The consumer behavior data can be generated based on advertisements and digital advertisements assets relative to the individual consumer.
    Type: Application
    Filed: March 14, 2018
    Publication date: April 4, 2019
    Inventors: Jillian Lee Shapiro, James Frederick Caruso, Jona Mici
  • Publication number: 20140221327
    Abstract: Known or suspected traumatic brain injuries may be treated therapeutically by administering a therapeutically effective dose of resibufogenin. A preferred method for determining if a patient has a traumatic brain injury includes obtaining a body specimen from the patient, determining the concentration of marinobufagenin in the body specimen, comparing the concentration of marinobufagenin to the concentration in such body specimens in normal patients, and if the marinobufagenin concentration is substantially above the concentration of a normal patient, concluding traumatic brain injury exists. In a preferred embodiment, a substantial elevation is deemed to be an increase of about 30 percent above the marinobufagenin concentration of a normal patient. The body specimen may be blood, urine, or cerebrospinal fluid.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 7, 2014
    Inventors: Jules B. Puschett, Lee Shapiro
  • Patent number: 8642568
    Abstract: Known or suspected traumatic brain injuries may be treated therapeutically by administering a therapeutically effective dose of resibufogenin. A preferred method for determining if a patient has a traumatic brain injury includes obtaining a body specimen from the patient, determining the concentration of marinobufagenin in the body specimen, comparing the concentration of marinobufagenin to the concentration in such body specimens in normal patients, and if the marinobufagenin concentration is substantially above the concentration of a normal patient, concluding traumatic brain injury exists. In a preferred embodiment, a substantial elevation is deemed to be an increase of about 30 percent above the marinobufagenin concentration of a normal patient. The body specimen may be blood, urine, or cerebrospinal fluid.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: February 4, 2014
    Inventors: Jules B. Puschett, Lee Shapiro
  • Publication number: 20110319372
    Abstract: Known or suspected traumatic brain injuries may be treated therapeutically by administering a therapeutically effective dose of resibufogenin. A preferred method for determining if a patient has a traumatic brain injury includes obtaining a body specimen from the patient, determining the concentration of marinobufagenin in the body specimen, comparing the concentration of marinobufagenin to the concentration in such body specimens in normal patients, and if the marinobufagenin concentration is substantially above the concentration of a normal patient, concluding traumatic brain injury exists. In a preferred embodiment, a substantial elevation is deemed to be an increase of about 30 percent above the marinobufagenin concentration of a normal patient. The body specimen may be blood, urine, or cerebrospinal fluid.
    Type: Application
    Filed: June 15, 2011
    Publication date: December 29, 2011
    Applicant: SCOTT & WHITE HEALTHCARE
    Inventors: JULES B. PUSCHETT, LEE SHAPIRO
  • Publication number: 20110112017
    Abstract: Embodiments herein concern compositions and methods for treating diabetes in a subject.
    Type: Application
    Filed: June 11, 2010
    Publication date: May 12, 2011
    Inventors: Lee SHAPIRO, Charles A. DINARELLO, Eli LEWIS, Peter GOTTLIEB, Amy WALLACE, Aaron MICHELS, Gregory B. POTTS
  • Patent number: 7732696
    Abstract: An instantly playable stringed instrument having a body, neck and fret spaces is provided. The instrument includes a plurality of strings. The strings are tuned such that in combination the sound they produce is an open E minor chord. The instantly playable stringed instrument may further include a plurality of indicators, each indicator corresponding to one fret space. Each indicator indicates a minor chord to be played by depressing all the strings within the fret space the indicator is associated with. The stringed instrument may further include a minor third string that has a color identification to distinguish it from the rest of the plurality of strings. The minor third string may be depressed on an adjacent fret space thereby converting the minor chord associated with the fret space having all strings depressed to a major chord.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: June 8, 2010
    Inventor: Lee Shapiro
  • Patent number: 6375584
    Abstract: An apparatus for enhancing in simulated real-time environment, the skills of a football place kicker, center and holder, particularly the speed, distance, direction and angle of the kicks, by simulating charging lineman and providing simultaneous and integrally connected, resettable, visually displayed split-time and total elapsed timing feedback comprising uprights, a cross bar supporting a net, actuator switches for cross bar, timing means, and time display and reset means on the time display.
    Type: Grant
    Filed: August 25, 2000
    Date of Patent: April 23, 2002
    Inventor: Stan Lee Shapiro
  • Patent number: 6246782
    Abstract: A system for automated detection of cancerous masses in mammograms initially identifies regions of interest (ROIs) using Fourier analysis (e.g., by means of an optical correlator). Context data is extracted from the mammogram for each ROI, such as size, location, ranking, brightness, density, and relative isolation from other ROIs. The pixels in the ROI are averaged together to create a smaller array of super-pixels, which are input into a first neural net. A second neural net receives the output values from the first neural net and the context data as inputs and generates an output score indicating whether the ROI contains a cancerous mass. The second neural net can also be provided with context data from another view of the same breast, the same view of the other breast, or a previous mammogram for the same patient.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: June 12, 2001
    Assignee: Lockheed Martin Corporation
    Inventors: Gary Lee Shapiro, Davis ReGoalt Oliver, Jr.
  • Patent number: 6116977
    Abstract: The present invention is directed to a donation container system which includes a sensor for detecting the approach of one or more individuals to the container. The container system also includes a microprocessor and a speaker, so that when the sensor detects the approach of one or more individuals to the container, it sends a signal to the microprocessor which in turn communicates with a voice chip. The voice chip then sends an audio signal to an output speaker so as to produce an audio output.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: September 12, 2000
    Assignee: Chaim T. Tanny
    Inventors: Chaim T. Tanny, John Chan, Lee Shapiro