Abstract: A flow regulation system for regulating a flow of a fluid from a fluid reservoir is disclosed having a fluid reservoir container, an effluent conduit adapted to discharge fluid from the fluid reservoir container, and a fluid turbine disposed in the effluent conduit. A generator is operatively connected to the fluid turbine for converting mechanical energy of the fluid turbine to electrical energy, and a power conditioning module is energized by the generator to alter voltage and current characteristics of electricity generated by the generator. A load manager is provided to monitor operational characteristic of the flow regulation systems.

Abstract: An apparatus that floats at the surface of a body of water over which waves pass, causing a nominally vertical axis of the apparatus to tilt away from an axis normal to the resting surface of the body of water. Tilting allows a fluid to flow through a channel that in an un-tilted apparatus would require the gravitational potential energy of the fluid to increase (i.e., to flow uphill), but, because of the tilt allows the fluid to flow through the channel in a downhill direction. Successive wave-driven tilts of the apparatus incrementally raise water to a head from which a portion of its gravitational potential energy can be converted to electrical power by causing the water to return to a lower level by flowing through a water turbine, or through some other apparatus that performs a useful function when supplied with a flow of high-pressure water.

Abstract: A buoyant wave energy device is disclosed that incorporates an open-bottomed tube of substantial length in which is partially enclosed a first body of water that oscillates in response to wave action. The device incorporates a buoy to which an upper end of the tube is connected and inside of which is trapped a second body of water of substantial mass. A differential phase in the oscillations of the water trapped in the tube, and the oscillations of the buoy of augmented mass, result in the periodic compression of a pocket of air trapped at the top of the tube, and in the subsequent expulsion of pressurized air through a turbine, thereby generating electrical power.

Abstract: A pressure-regulating buoyant hydrodynamic pump is disclosed that floats adjacent to a surface of a body of water over which waves tend to pass. In response to wave-induced movements of the device, water is drawn into a mouth at a lower end of an injection tube, and water is ejected from a mouth at an upper end of the injection tube. The ejected water is deposited into an interior of the hollow buoy thereby augmenting a water reservoir therein. And water flows from the water reservoir to and through a water turbine, thereby energizing a generator, power electronics, and an electrical load. A novel water-turbine effluent buffering tube, or chamber, smooths pressure variations felt across the water turbine.

Abstract: The present invention relates to antibodies that specifically bind to one or more of IL-4, IL-13, IL-33, TSLP, and p40. The present invention further relates to antibodies that bind to one of IL-4, IL-13, IL-33, or TSLP. The invention further relates to multispecific antibodies that specifically bind to IL-4 and IL-13, and at least one other target. The present invention relates to multispecific antibodies that bind IL-4, IL-13, and one of IL-33, TSLP, or p40. The present invention also pertains to related molecules, e.g. nucleic acids which encode such antibodies or multispecific antibodies, compositions, and related methods, e.g., methods for producing and purifying such antibodies and multispecific antibodies, and their use in diagnostics and therapeutics.

Abstract: A computing apparatus that is integrated within a flotation module, the system obtaining the energy required to power its computing operations from waves that travel across the surface of a body of water on which the flotation module sets. Additionally, the self-powered computing apparatus employs novel designs to utilize its close proximity to the body of water and/or to strong ocean winds to significantly lower the cost and complexity of cooling their computing circuits.

Abstract: Disclosed is an autonomous vessel comprising a hydrodynamic pump that converts the energy of ocean waves into electrical power when the vessel is floating adjacent to an upper surface of an ocean, and utilizes a portion of the generated electrical power produced to charge an electrical energy storage device. The vessel may submerge itself, and then propel itself beneath the water's surface, after which it may return to the surface and resume its production of electrical energy and recharge its electrical energy storage device.

Abstract: A method of treating patients who are positive for Helicobacter pylori infection comprises determining that a first patient who is positive for Helicobacter pylori infection has a body mass index corresponding to normal weight or overweight; determining that a second patient who is positive for Helicobacter pylori infection has a body mass index corresponding to obese or extremely obese; and administering to both the first patient and the second patient, for 14 days, a rifabutin-based triple therapy consisting essentially of rifabutin, amoxicillin and omeprazole or an equivalent amount of a pharmaceutically acceptable salt thereof, wherein, after treatment is complete, there is no substantial difference in the efficacy of the treatment when the treatment is administered to the first patient or the second patient.

Abstract: A method by which an environmental energy (e.g., wave energy) is harvested, converted into electrical power, and thereafter used to electrolyze seawater into hydrogen and chlorine gases. Those gases are recombined into hydrogen chloride from which is formed hydrochloric acid solution which is diluted and deposited at a depth sufficient to ensure its neutralization and sequestration for a significant period of time (e.g., for over a millennium). By removing chloride ions from a portion of the sea adjacent to its upper surface and depositing them into a portion of the sea more adjacent to its bottom, acidity is shifted from the surface to base of the sea, and the surface ocean is given a greater ability to absorb and buffer atmospheric carbon dioxide without a corresponding increase in acidity.

Abstract: A method of treating patients who are positive for Helicobacter pylori infection comprises determining that a first patient who is positive for Helicobacter pylori infection has a body mass index corresponding to normal weight or overweight; determining that a second patient who is positive for Helicobacter pylori infection has a body mass index corresponding to obese or extremely obese; and administering to both the first patient and the second patient, for 14 days, a rifabutin-based triple therapy consisting essentially of rifabutin, amoxicillin and omeprazole or an equivalent amount of a pharmaceutically acceptable salt thereof, wherein, after treatment is complete, there is no substantial difference in the efficacy of the treatment when the treatment is administered to the first patient or the second patient.

Abstract: A method of treating patients who are positive for Helicobacter pylori infection comprises determining that a first patient who is positive for Helicobacter pylori infection has a body mass index corresponding to normal weight or overweight; determining that a second patient who is positive for Helicobacter pylori infection has a body mass index corresponding to obese or extremely obese; and administering to both the first patient and the second patient, for 14 days, a rifabutin-based triple therapy consisting essentially of rifabutin, amoxicillin and omeprazole or an equivalent amount of a pharmaceutically acceptable salt thereof, wherein, after treatment is complete, there is no substantial difference in the efficacy of the treatment when the treatment is administered to the first patient or the second patient.

Abstract: A portable, lightweight desk designed for comfortable performance by being simple, compact, and designed to provide easy adjustment to a desirable angular position for the work surface during a task of reading, drawing, or even painting, while pertinent equipment and supplies are available within an enclosed storage space. The portable desk was especially constructed to provide a desk which is available for many tasks while storing pertinent components. The desk will have a trim, sleek, and well-designed appearance. I have particularly constructed the surface of the lower member to be covered with a soft material to be comfortable on the user's lap. The user may then comfortably read, write, or draw when in a relaxed position. I have found a component of foam plastic efficient in use as a book support to maintain page control.

Abstract: A paper pallet generally comprises support blocks, a top pad, and a wrap. The support blocks are of a comb configuration, e.g., honeycomb or hexacomb. The top pad is of a corrugated material and is positioned above the support blocks. The wrap is also of a corrugated material and wraps, via direct contact, the top and side surfaces of the top pad as well as wrapping, via direct contact, at least two side surfaces of the support blocks.