Abstract: Methods for treating a disease, condition, or disorder associated with impaired muscle regeneration, including a muscular dystrophy, such as Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD), or limb-girdle muscular dystrophy (LGMD), by administering a PPAR? agonist to a subject. The PPAR? agonist can be one or more thiazolidinediones including, but not limited to pioglitazone and rosiglitazone.

Abstract: The instant disclosure relates to compositions and methods that include NOX4 inhibitors as therapeutic agents capable not only of reducing fibrosis in muscle tissues of subjects having or at risk of developing a muscular dystrophy but also of inducing muscle tissue regeneration, by a mechanism apparently involving activation of fibro-adipogenic progenitor (FAP) cells.

Abstract: The present invention relates to a collapsible device for assisting a construction worker in erecting a framed wall. The device includes an elongated telescoping arm having a planar foot member at a first end thereof for vertically securing the arm to a floor. A first end of an elongated nylon strap is attached to a retraction mechanism on the arm. A second end of the nylon strap has a bracket thereon for securing to the top of a wall. The telescoping arm has a weight indication means for indicating to a user the weight of a wall being erected thereby. Accordingly, the strap may be secured to a horizontally oriented wall and the nylon strap is retracted causing the wall to pivot to a vertical position. The telescoping arm allows the device to be easily collapsed for transport or storage.