Patents by Inventor Lee Terence Boulton

Lee Terence Boulton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of enantiomeric indanylamine derivatives
    Patent number: 7476757
    Abstract: A process for manufacturing (R)-propynylaminoindans, and alternatively, a process for manufacturing (S)-propynylaminoindans. The chiral propynylaminoindans include alkoxy or alkylcarbamates derivatives. The process comprises transfer or pressure hydrogenation in the presenc of an optically active catalyst to reduce 1-indanones. The chiral product, either (S)- or (R)-indanols undergo nucleophilic substitution to produce the named product. In an additional aspect, the invention relates to novel intermediates and compounds, namely, substituted indanones, substituted (S)-indanols and substituted (R)-indanols.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: January 13, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Lee Terence Boulton, Ian Campbell Lennon, Eliezer Bahar
  • PROCESS FOR THE SYNTHESIS OF ENANTIOMERIC INDANYLAMINE DERIVATIVES
    Publication number: 20080200720
    Abstract: A process for manufacturing (R)-propynylaminoindans, and alternatively, a process for manufacturing (S)-propynylaminoindans. The chiral propynylaminoindans include alkoxy or alkylcarbamates derivatives. The process comprises transfer or pressure hydrogenation in the presence of an optically active catalyst to reduce 1-indanones. The chiral product, either (S)- or (R)-indanols undergo nucleophilic substitution to produce the named product. In an additional aspect, the invention relates to novel intermediates and compounds, namely, substituted indanones, substituted (S)-indanols and substituted (R)-indanols.
    Type: Application
    Filed: April 15, 2008
    Publication date: August 21, 2008
    Applicant: Teva Pharmaceutical Industries Ltd.
    Inventors: Lee Terence Boulton, Ian Campbell Lennon, Eliezer Bahar
  • Process for the synthesis of enantiomeric indanylamine derivatives
    Patent number: 7375249
    Abstract: A process for manufacturing (R)-propynylaminoindans, and alternatively, a process for manufacturing (S)-propynylaminoindans. The chiral propynylaminoindans include alkoxy or alkylcarbamates derivatives. The process comprises transfer or pressure hydrogenation in the presence of an optically active catalyst to reduce 1-indanones. The chiral product, either (S)- or (R)-indanols undergo nucleophilic substitution to produce the named product. In an additional aspect, the invention relates to novel intermediates and compounds, namely, substituted indanones, substituted (S)-indanols and substituted (R)-indanols.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: May 20, 2008
    Assignee: TEVA Pharmaceutical Industries Ltd.
    Inventors: Lee Terence Boulton, Ian Campbell Lennon, Eliezer Bahar
  • Process for the production of quinazolines
    Patent number: 7026479
    Abstract: The invention provides a process for the production of a compound of formula (A), or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, and R4 are as defined herein.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: April 11, 2006
    Inventors: Lee Terence Boulton, Robert James Crook, Alan John Pettman, Robert Walton
  • Process for the production of quinazolines
    Publication number: 20030100753
    Abstract: The invention provides a process for the production of a compound of formula (A), or a pharmaceutically acceptable salt or solvate thereof, 1
    Type: Application
    Filed: July 19, 2002
    Publication date: May 29, 2003
    Applicant: Pfizer Inc.
    Inventors: Lee Terence Boulton, Robert James Crook, Alan John Pettman, Robert Walton