Patents by Inventor Leendert Marinus Schouls

Leendert Marinus Schouls has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and differentiation of mycobacterium tuberculosis complex bacteria by direct variant repeat oligotyping
    Patent number: 6074820
    Abstract: A method and primary pair and kit for the in vitro amplification of nucleic acid using amplification primers in amplification reactions. There is used a pair of primers comprising oligonucleotide sequences complementary to a part of a Direct Repeat sequence of a microorganism belonging to the M tuberculosis complex of microorganisms, whereby hybridization to a Direct Repeat occurs and subsequently elongation of the hybridized primer takes place. The primers are such that elongation in the amplification reaction occurs for one primer in a 5' direction and for the other primer in a 3' direction.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: June 13, 2000
    Assignee: De Staat der Nederlanden, Vertegenwoordigd door de Minister van Welzijn, Volksgezondhed en Cultuur
    Inventors: Johannes Dirk Anthonie Van Embden, Leendert Marinus Schouls, Judith Kamerbeek