Patents by Inventor Lei Chen
Lei Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250151606Abstract: The present disclosure provides a display device and a light emitting component. The light emitting component includes: an anode and a cathode arranged oppositely; a light emitting layer between the anode and the cathode, where the light emitting layer includes a host material and a dopant material, the host material includes hole type material and electron type material, the electron transport rate exceeds the hole transport rate in the light emitting layer; and an electron barrier layer on a surface of the light emitting layer facing the anode; where the hole type material, the electron type material, the dopant material, and the electron barrier layer or any combination thereof includes a deuterium-substituted compound.Type: ApplicationFiled: February 24, 2023Publication date: May 8, 2025Inventors: Yang LIU, Dan WANG, Lei CHEN
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Publication number: 20250147027Abstract: The invention provides a prostate cancer detection reagent and a preparation method thereof. The detection reagent is prepared by mixing the following reagents, reagent A is prepared by adding SDS with a mass concentration of 0.5˜5% into ammonium bicarbonate solution with a concentration of 10 mM; Reagent B was prepared by mixing 0.01-10 U/10 ?L glycoamidase and 0.01-10 U/10 ?L Sialidase, and the pH value of the mixed solution was 4-9. Reagent C: Prepared from 8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt dissolved in DMSO, the concentration is 0.01 mM˜1 M; Reagent D: Stopping solution. The invention determines the N-glycan profile in serum by the detection reagent, quantifies the peak value for statistical analysis, and provides a method for establishing a model of the N-glycan profile in serum of prostate cancer to detect prostate cancer.Type: ApplicationFiled: September 14, 2022Publication date: May 8, 2025Applicants: JIANGSU XIANSIDA BIOTECHNOLOGY CO., LTD., XIANSIDA NANJING BIOTECHNOLOGY CO., LTD.Inventors: Cuiying CHEN, Lei WANG, Zongnan TAN
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Publication number: 20250150735Abstract: This application discloses a CIS pixel readout circuit structure. An SG and an SF adopt different transverse thicknesses of spacers. The spacer of the SG adopts a smaller transverse thickness to reduce the parasitic resistance. The spacer of the SF adopts a larger transverse thickness to reduce the GIDL current. In the CIS pixel readout circuit structure according to this application, drain metal plugs are formed on outer sides of both left and right ends of an SF gate structure. The SF and the SG form a T-shaped combined compact structure to achieve equivalent parallel connection of two SF, thus effectively reducing the parasitic resistance of the share active area between the SG and the SF, and simultaneously saving the space area. This application further discloses a method for fabricating a CIS pixel readout circuit structure.Type: ApplicationFiled: August 20, 2024Publication date: May 8, 2025Applicant: Shanghai Huali Integrated Circuit CorporationInventors: Qiwei WANG, Zhen GU, Haoyu CHEN, Lei ZHANG, Zhi TIAN
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Publication number: 20250149655Abstract: The disclosure herein relates to rechargeable batteries and solid electrolytes therefore which include lithium-stuffed garnet oxides, for example, in a thin film, pellet, or monolith format wherein the density of defects at a surface or surfaces of the solid electrolyte is less than the density of defects in the bulk. In certain disclosed embodiments, the solid-state anolyte, electrolyte, and catholyte thin films, separators, and monoliths consist essentially of an oxide that conducts Li+ ions. In some examples, the disclosure herein presents new and useful solid electrolytes for solid-state or partially solid-state batteries. In some examples, the disclosure presents new lithium-stuffed garnet solid electrolytes and rechargeable batteries which include these electrolytes as separators between a cathode and a lithium metal anode.Type: ApplicationFiled: January 8, 2025Publication date: May 8, 2025Inventors: David CAO, Cheng-Chieh CHAO, Zhebo CHEN, Lei CHENG, Niall DONNELLY, Wes HERMANN, Timothy HOLME, Tommy HUANG, Kian KERMAN, Yang LI, Harsh MAHESHWARI
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Publication number: 20250149461Abstract: A multi-device graded embedding package substrate includes a first dielectric layer, a second dielectric layer, and a third dielectric layer. The first dielectric layer includes a first conductive copper pillar layer and a first device cavity. The second dielectric layer includes a first wiring layer located in a lower surface of the second dielectric layer, a second conductive copper pillar layer and a heat dissipation copper block layer provided on the first wiring layer. The third dielectric layer includes a second wiring layer, a third conductive copper pillar layer provided on the second wiring layer. A first device is attached to the bottom of the first device cavity, and a terminal of the first device is in conductive connection with the second wiring layer. A second device is attached to the bottom of a second device cavity penetrating through the first, second and third dielectric layers.Type: ApplicationFiled: January 7, 2025Publication date: May 8, 2025Inventors: XIANMING CHEN, LEI FENG, BENXIA HUANG, YEJIE HONG
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Publication number: 20250147122Abstract: A device for detecting electric leakage, includes: a detection assembly connected to a first phase discharge path, a second phase discharge path, and a sampling assembly which is connected to a signal processing circuit. The first and the second phase discharge paths are configured to connect to a power supply and transmit electricity from the power supply when the power supply discharges electricity. The detection assembly is configured to establish the detection loop when the power supply discharges electricity. The sampling assembly is configured to collect, from the detection loop, a first detected voltage of the first phase discharge path and a second detected voltage of the second phase discharge path. The signal processing circuit is configured to receive the first and the second detected voltages from the sampling assembly, and determine whether the power supply has electric leakage according to the first and the second detected voltages.Type: ApplicationFiled: January 10, 2025Publication date: May 8, 2025Inventors: Mingwen CHEN, Penghui XUE, Xiangxiang LI, Lei SHI, Weicheng LI
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Publication number: 20250146731Abstract: An internal circulation type clathrate hydrate-based cold storage system and method are provided in the field of industrial refrigeration. The internal circulation type clathrate hydrate-based cold storage system includes a water chilling unit, a hydrate-based cold storage tank, a gas disturbance device, a concentration measurement system, a heat exchange system, a direct-current power supply and circuit control system, and a system monitoring device. The water chilling unit provides a secondary refrigerant at a low temperature. The secondary refrigerant flows through an evaporator coil in the hydrate-based cold storage tank for a heat exchange. The gas disturbance device induces hydrate nucleation. The concentration measurement system monitors a concentration of a hydrate solution in real time. The heat exchange system is equipped with a finned tube heat exchanger with a fan.Type: ApplicationFiled: December 9, 2022Publication date: May 8, 2025Applicant: DALIAN UNIVERSITY OF TECHNOLOGYInventors: Yongchen SONG, Yuan LV, Lunxiang ZHANG, Chuanxiao CHENG, Mingjun YANG, Yu LIU, Fan WANG, Lei YANG, Yi ZHANG, Zheng LING, Yanghui LI, Cong CHEN, Peng WU, Bingbing CHEN
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Publication number: 20250151424Abstract: This application discloses a CIS pixel readout structure. An SF and an SG adopt an asymmetric spacer structure, so that the pitch from a lower end of a source metal plug of the SG to SG gate poly can be reduced while keeping the pitch from a lower end of a drain metal plug of the SF to SF gate poly unchanged, thus reducing the pitch from a drain connecting point of the SF to a source connecting point of the SG. Since a source of the SG is not connected with working voltage and it is not influenced by leakage, not only can GIDL current be maintained, but also parasitic resistance can be reduced. Without changing its effective size, it can reduce the parasitic resistance effect while reducing the area of a combined structure of the SF and the SG.Type: ApplicationFiled: July 24, 2024Publication date: May 8, 2025Applicant: Shanghai Huali Integrated Circuit CorporationInventors: Qiwei WANG, Zhen Gu, Haoyu Chen, Lei Zhang, Zhi Tian
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Patent number: 12294163Abstract: An antenna is provided and includes a bottom plate for being connected with a mounting body and an antenna body on the bottom plate. The antenna body includes: a substrate fixedly connected to the bottom plate; a plane of the substrate intersects the bottom plate; a radiation element on the substrate; a feeding structure configured to transmit and/or receive radio frequency signals to/from the radiation element and including a signal electrode and a ground electrode on a surface of the substrate. The signal electrode is electrically connected to the radiation element. On a reference plane perpendicular to the bottom plate, an orthographic projection of the ground electrode is spaced apart from that of the radiation element, and is entirely located between the orthographic projection of the radiation element and the bottom plate. The antenna can prevent the ground electrode from reflecting the electromagnetic waves radiated by the radiation element.Type: GrantFiled: February 22, 2022Date of Patent: May 6, 2025Assignees: Beijing BOE Sensor Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Yunnan Jin, Zhe Chen, Shuo Yang, Lei Wang
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Patent number: 12294507Abstract: This application discloses a service level configuration methods and apparatuses, and belongs to the field of communications network technologies. According to an example method, a target service level used by a first forwarding node to forward a data flow is directly determined based on a transmission parameter of the data flow and service level information of the first forwarding node, and service level configuration is performed on the first forwarding node. Because a transmission parameter of the target service level of the first forwarding node and the transmission parameter of the data flow meet a first target condition, if the first target condition is a delay requirement required by a special service and the first forwarding node transmits the data flow by using the target service level, transmission of the data flow may meet the delay requirement required by the special service.Type: GrantFiled: July 20, 2022Date of Patent: May 6, 2025Assignee: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Lihao Chen, Jiayi Zhang, Lei Li, Shuang Chen
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Publication number: 20250134019Abstract: The present disclosure relates to recombinant DNA molecules and engineered proteins useful for conferring tolerance to ?-triketone herbicides such as mesotrione. The present disclosure also provides herbicide tolerant transgenic plants, plant parts, cells and seeds comprising the recombinant DNA molecules, and methods of using the same.Type: ApplicationFiled: February 6, 2023Publication date: May 1, 2025Inventors: Danqi Chen, Shunhong Dai, David Duda, Stephen M. Duff, Clayton Larue, Qungang Qi, Lei Shi, Christina Taylor
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Publication number: 20250134987Abstract: The current disclosure includes coronavirus vaccines that protect against pathogenic coronavirus species, as well as their variants. In certain embodiments, SARS-CoV-2 variant specific and multivalent coronavirus vaccines are described. The vaccines typically include a modified mRNA which encodes at least one coronavirus derived immunogen, such as a spike protein or a fragment thereof. The mRNA can be encapsulated into lipid nanoparticles or other carriers and formulated as pharmaceutical compositions which can be used to generate an immune response to coronavirus in a subject. The vaccines can be used to elicit potent B and T cell responses against SARS-CoV-2 variants and to confer protective immunity against SARS-CoV-2, as well as other pathogenic coronavirus species such as SARS-CoV and/or MERS-CoV.Type: ApplicationFiled: October 14, 2022Publication date: May 1, 2025Inventors: Sidi Chen, Lei Peng, Zhenhao Fang, Jonathan Park, Matthew Dong, Xiaoyu Zhou, Paul Renauer
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Publication number: 20250142990Abstract: The present disclosure provides an image sensor and a method of manufacturing the same. The image sensor includes a substrate and a gate electrode. The gate electrode is disposed proximate to a first side of the substrate. The gate electrode includes a first gate portion, a second gate portion, and a third gate portion. The first gate portion is disposed over the first side of the substrate. The second gate portion is disposed within the substrate and connected to the first gate portion. The third gate portion is disposed below and connected to the second gate portion. A first width of the first gate portion is greater than a second width of the second gate portion, and a third width of the third gate portion is greater than the second width.Type: ApplicationFiled: February 19, 2024Publication date: May 1, 2025Inventors: Chung-Lei Chen, Yen-Liang Lin, Ru-Shang Hsiao
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Publication number: 20250134983Abstract: A viral vector delivery system for both respiratory and digestive tracts of pigs and an application thereof are provided. The viral vector delivery system includes a backbone plasmid and a helper plasmid. The backbone plasmid is produced by inserting a full-length cDNA of porcine enterovirus B (PEVB) into a pUC57 plasmid. The helper plasmid is produced by inserting a green fluorescent protein-coding gene into a plasmid pCAG-T7-polymerase. The viral vector delivery system can be constructed with high efficiency, can quickly cause a cytopathic effect (CPE) after infecting cells, has a viral titer up to 107.75 TCID50/mL, and can maintain high stability. A pathogenic epitope for the respiratory and digestive tracts of pigs is inserted into the backbone plasmid to produce a vaccine antigen, which is non-pathogenic, has high stability and a high viral titer, and allows a prominent immunization effect after being inoculated in pigs.Type: ApplicationFiled: January 8, 2025Publication date: May 1, 2025Applicants: JIANGSU ACADEMY OF AGRICULTURAL SCIENCES, SNU R&DB FOUNDATION, GUOTAI (TAIZHOU) CENTER OF TECHNOLOGY INNOVATION FOR VETERINARY BIOLOGICALS, TAIZHOUInventors: Xing XIE, Zhixin FENG, Daesub SONG, Rong CHEN, Fei HAO, Lulu XU, Minjoo YEOM, Jongwoo LIM, Lei ZHANG, Yuan GAN, Long ZHAO, Wenliang LI, Qiyan XIONG, Yongjie LIU, Beibei LIU, Yanfei YU, Yun BAI, Guoqing SHAO
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Publication number: 20250136694Abstract: Provided is an anti-B7-H4 antibody containing a VH, wherein the VH contains the following CDRs or a mutation thereof: CDR1 as shown in the amino acid sequence of SEQ ID NO: 4 or 5, CDR2 as shown in the amino acid sequence of SEQ ID NO: 15, and CDR3 as shown in the amino acid sequence of SEQ ID NO: 24 or 25, and wherein the mutation is an insertion, deletion or substitution of 3, 2 or 1 amino acid(s) in the amino acid sequences of the CDRs. The antibody has the activity of binding to human B7-H4 and cynomolgus monkey B7-H4. The antibody still retains the activity of binding to human B7-H4 and cynomolgus monkey B7-H4 when prepared into a B7-H4×CD3 bispecific antibody, and has a strong killing effect on tumor cells. The antibody induces a very low expression of nonspecific cytokines such as IL-6 and IFN-?, and exhibits a strong in vivo anti-tumor activity.Type: ApplicationFiled: August 16, 2022Publication date: May 1, 2025Applicant: HARBOUR BIOMED (SHANGHAI) CO., LTDInventors: Xiaodong WU, Yongqiang WANG, Gezi JIA, Chuchu ZHAO, Fei CHEN, Yun HE, Yiping RONG, Yi DING, He LI, Lei NIU
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Patent number: 12286037Abstract: An automobile seat integrated with height adjustment and angle adjustment comprises a seat body comprising a pedestal skeleton and a backrest skeleton, a height adjustment mechanism comprising a bottom support, a rear connection rod, an upper connection rod and a front connection rod and an angle adjustment mechanism comprising the bottom support, an angle adjustment connection rod, a driving connection rod, a front connection rod and the upper connection rod, the bottom support, the front connection rod and the upper connection rod are common parts of the height adjustment mechanism and the angle adjustment mechanism, the bottom support, the rear connection rod, the upper connection rod and the front connection rod are successively adjacently connected by rotating pairs, and the rear connection rod is connected with a height adjustment driving source which drives the rear connection rod to move when working to realize the height adjustment of the automobile seat.Type: GrantFiled: December 23, 2022Date of Patent: April 29, 2025Assignee: Magna Seating Research & Development (Chongqing) Co., Ltd.Inventors: Jiale Zuo, Guogang Chen, Lei Xue
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Patent number: 12285013Abstract: The present invention relates to a processing method for increasing seed production rate of seed fruits of Cucumis sativus L., comprising the following steps: (1) preparing a plant growth regulator according to a formula proportion; (2) selecting seed fruits of Cucumis sativus L. growing naturally in a greenhouse and reaching a pollination stage, and dipping female flowers thereof with the plant growth regulator prepared in step (1) before pollination; (3) picking male flowers for pollination after the female flowers are completely dry; (4) dipping the pollinated female flowers again; (5) conducting field routine cultivation management. The present invention uses a DNA methyltransferase inhibitor “5-azacytidine” (C8H12N4O5) to treat the seed fruits of Cucumis sativus L. by soaking and dipping, wherein 5-azacytidine increases seed production efficiency by reducing fruit length of the seed fruits, reducing fruit weight and reducing nutrient loss for fruit growth.Type: GrantFiled: August 27, 2024Date of Patent: April 29, 2025Assignee: Yangzhou UniversityInventors: Xiaodong Yang, Yizhuo Deng, Lili Zhang, Lei Qiu, Jieni Gu, Xuehao Chen
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Patent number: 12288726Abstract: An array substrate, a display panel and methods of manufacturing the same are provided. The method of manufacturing an array substrate according to an embodiment of the present disclosure includes: forming f pixel electrodes and a conductive structure on a substrate through a patterning process, wherein the pixel electrodes arranged in a first direction are connected through the conductive structure; and forming a signal line on the substrate through a patterning process, wherein the signal line and the pixel electrodes are disposed in the same layer. By means of the array substrate according to the embodiments of the present disclosure, the problem that it is not easy to discover the point defects caused by short circuit between the signal line and pixel electrodes in the related art can be solved.Type: GrantFiled: May 27, 2021Date of Patent: April 29, 2025Assignees: Hefei Xinsheng Optoelectronics Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Yu Ji, Guoping Qian, Lei Feng, Wanqing Chen, Lingling Zeng, Xianchun Huang, Chao Zhou, Youpeng Gan
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Patent number: 12287521Abstract: Disclosed is a photodetector with a resonant waveguide structure, including: a substrate; a light absorption layer located on the substrate and configured for detecting an optical signal; a resonant waveguide structure including a first waveguide portion and a second waveguide portion spaced apart; the first waveguide portion receives the optical signal and transmits the received optical signal to a first region of the second waveguide portion, the second waveguide portion includes a second region for coupling the optical signal to the light absorption layer, and the second waveguide portion provides a circular transmission path for transmission of the optical signal to transmit the optical signal that transmitted to the first region to the second region along part of the circular transmission path and retransmit the optical signal that flows through the second region without being coupled to the light absorption layer to the second region along the circular transmission path.Type: GrantFiled: December 4, 2020Date of Patent: April 29, 2025Assignee: WUHAN OPTICAL VALLEY INFORMATION OPTOELECTRONICS INNOVATION CENTER CO., LTDInventors: Xiao Hu, Xi Xiao, Daigao Chen, Lei Wang, Yuguang Zhang, Miaofeng Li
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Patent number: 12288794Abstract: An image sensor includes a storage device, where the storage device includes a memory element, a first dielectric layer and a light shielding element. The memory element includes a storage node and a storage transistor gate, where the storage transistor gate is located over the storage node. The first dielectric layer is located over a portion of the storage transistor gate. The light shielding element is located on the first dielectric layer and includes a semiconductor layer. The semiconductor layer is electrically isolated from the memory element, where the light shielding element is overlapped with at least a part of a perimeter of the storage transistor gate in a vertical projection on a plane along a stacking direction of the memory element and the light shielding element, and the stacking direction is normal to the plane.Type: GrantFiled: April 18, 2023Date of Patent: April 29, 2025Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: Chung-Lei Chen, Clark Lee, Wen-Sheng Wang, Chien-Li Kuo