Patents by Inventor Lei Hamilton

Lei Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10318608
    Abstract: Systems and methods may identify at least a first set of right singular vectors and a first set of singular values of a subset of the matrix, reduce the subset by an amount of energy of a selected data entry of the subset based on the first set of right singular vectors and the first set of singular values, incorporate a new data entry from the matrix into the subset, update the first set of right singular vectors and the first set of singular values of the subset based on the new data entry by a singular value decomposition (SVD) update, and generate the low-rank approximation of the matrix based on the updated first set of right singular vectors and the updated first set of singular values.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: June 11, 2019
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Timothy Galvin, Christopher C. Yu, Piotr Indyk, Lei Hamilton, William Whitacre
  • Patent number: 10219688
    Abstract: The present disclosure describes systems and methods to select fovea containing optical coherence tomography (OCT) images. The systems and methods described herein receive a plurality of OCT images. The portion of the OCT images are selected for further processing, where a line tracing the border between the retina and non-retina tissue is generated. A difference of the line is generated. Candidate OCT images are then generated responsive to the generated difference line. The lowest point among each difference lines generated for each of the OCT images is identified, and the OCT image to which the lowest point corresponds is identified as the fovea containing OCT image.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: March 5, 2019
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Nathan Lowry, Peter Lommel, Lei Hamilton, Rami Mangoubi
  • Patent number: 10062162
    Abstract: The present disclosure describes a system and method to segment optical coherence tomography (OCT) images. The present system uses a hybrid method that employs both Bayesian level sets (BLS) and graph-based segmentation algorithms. The system first identifies retinal tissue within an OCT image using the BLS algorithms. The identified retinal tissue is then further segmented using the graph-based segmentation algorithms.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: August 28, 2018
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Nathan Lowry, Peter Lommel, Rami Mangoubi, Richard Wood, Lei Hamilton, John Irvine, Stephen Duncan
  • Publication number: 20170105616
    Abstract: The present disclosure describes systems and methods to select fovea containing optical coherence tomography (OCT) images. The systems and methods described herein receive a plurality of OCT images. The portion of the OCT images are selected for further processing, where a line tracing the border between the retina and non-retina tissue is generated. A difference of the line is generated. Candidate OCT images are then generated responsive to the generated difference line. The lowest point among each difference lines generated for each of the OCT images is identified, and the OCT image to which the lowest point corresponds is identified as the fovea containing OCT image.
    Type: Application
    Filed: October 18, 2016
    Publication date: April 20, 2017
    Inventors: Nathan Lowry, Peter Lommel, Lei Hamilton, Rami Mangoubi, Richard Wood, John Irvine, Stephen Duncan, David O'Dowd
  • Publication number: 20170109883
    Abstract: The present disclosure describes a system and method to segment optical coherence tomography (OCT) images. The present system uses a hybrid method that employs both Bayesian level sets (BLS) and graph-based segmentation algorithms. The system first identifies retinal tissue within an OCT image using the BLS algorithms. The identified retinal tissue is then further segmented using the graph-based segmentation algorithms.
    Type: Application
    Filed: October 18, 2016
    Publication date: April 20, 2017
    Inventors: Nathan Lowry, Peter Lommel, Rami Mangoubi, Richard Wood, Lei Hamilton, John Irvine, Stephen Duncan
  • Publication number: 20160055124
    Abstract: Systems and methods for generating a low-rank approximation of a matrix are provided. The various systems and methods may identify at least a first set of right singular vectors and a first set of singular values of a subset of the matrix, reduce the subset by an amount of energy of a selected data entry of the subset based on the first set of right singular vectors and the first set of singular values, incorporate a new data entry from the matrix into the subset, update the first set of right singular vectors and the first set of singular values of the subset based on the new data entry by a singular value decomposition (SVD) update, and generate the low-rank approximation of the matrix based on the updated first set of right singular vectors and the updated first set of singular values.
    Type: Application
    Filed: August 21, 2015
    Publication date: February 25, 2016
    Inventors: Timothy Galvin, Christopher C. Yu, Piotr Indyk, Lei Hamilton, William Whitacre