Patents by Inventor Lei Hua
Lei Hua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240126764Abstract: Techniques support graph pattern matching queries inside a relational database management system (RDBMS) that supports SQL execution. The techniques compile a graph pattern matching query that includes a bounded recursive pattern query into a SQL query that can then be executed by the relational engine. As a result, techniques enable execution of graph pattern matching queries that include bounded recursive patterns on top of the relational engine by avoiding any change in the existing SQL engine.Type: ApplicationFiled: October 13, 2022Publication date: April 18, 2024Inventors: VLAD IOAN HAPRIAN, LEI SHENG, LAURENT DAYNES, ZHEN HUA LIU, HUGO KAPP, MARCO ARNABOLDI, ANDREW WITKOWSKI, SUNGPACK HONG, HASSAN CHAFI
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Publication number: 20240122917Abstract: Disclosed is the use of a composition containing cilostazol or a pharmaceutically acceptable salt thereof and edaravone in the preparation of a drug for treating cerebrovascular diseases, especially ischemic cerebrovascular diseases. The experiment result shows that the tail vein administration of 1-15 mg/kg of cilostazol or 1.67-8.33 mg/kg of edaravone on rats with a focal cerebral ischemia-reperfusion injury can significantly ameliorate neurological defects in rats with an MCAO and reduce a cerebral infarction area; and performing compound combination within the dosage range (the mass ratio of cilostazol:edaravone is 1:5 to 5:1) can be synergistic. The tail vein administration of 3.33-16.67 mg/kg of cilostazol or 3.33-16.67 mg/kg of edaravone on mice with a focal cerebral ischemia-reperfusion injury can significantly ameliorate neurological defects in mice with an MCAO and reduce a cerebral infarction area.Type: ApplicationFiled: January 26, 2022Publication date: April 18, 2024Applicant: NEURODAWN PHARMACEUTICAL CO., LTD.Inventors: Yao HUA, Lei WANG, Zhengping ZHANG, Rong CHEN, Shibao YANG
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Publication number: 20240082234Abstract: The present invention belongs to the pharmaceutical field, and relates to an application of a cilostazol and d-borneol composition in preparing a drug for treating cerebrovascular disease, in particular ischemic cerebrovascular disease. The present invention specifically relates to a composition containing cilostazol or a pharmaceutically acceptable salt thereof and d-borneol, and an application of the composition in preparing a drug for treating cerebrovascular disease, in particular ischemic cerebrovascular disease.Type: ApplicationFiled: January 12, 2022Publication date: March 14, 2024Applicant: NEURODAWN PHARMACEUTICAL CO., LTD.Inventors: Yao HUA, Lei WANG, Zhengping ZHANG, Rong CHEN, Shibao YANG
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Publication number: 20240081271Abstract: A dust removal-sterilization-deodorization integrated intelligent lightweight device for livestock and poultry houses includes: a transparent housing, a photocatalyst slidably connected to an inner wall of the transparent housing, filter sleeves rotatably mounted on the inner wall of the transparent housing, a flow guide cavity defined in the transparent housing, a fan fixedly connected to a left sidewall of the flow guide cavity, and a flow baffle fixedly connected to an air inlet end of the flow guide cavity. The filter sleeve includes a low-resistance melt-blown fabric, a rutile manganese-zinc layer is laid on an outer side of the low-resistance melt-blown fabric, a skeleton fabric is attached to an outer wall of the rutile manganese-zinc layer, and an outer wall of the skeleton fabric is rotatably connected to the inner wall of the transparent housing. At least two filter sleeves are transversely arranged, and the filter sleeves are tubular.Type: ApplicationFiled: November 19, 2023Publication date: March 14, 2024Inventors: Zhifang Shi, Lei Xi, Xuanyang Li, Pu Cheng, Chunhui Hua, Sixin Zhang, Limin Wang
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Patent number: 11447543Abstract: Antibodies and antigen binding fragments thereof directed against Staphylococcus aureus (S. aureus) surface determinant antigens and secreted toxins are disclosed. Methods of detecting, diagnosing and treating S. aureus using the antibodies and antigen binding fragments thereof are also provided.Type: GrantFiled: July 9, 2020Date of Patent: September 20, 2022Assignee: MedImmune, LLCInventors: Bret Sellman, Christine Tkaczyk, Partha S. Chowdhury, Lei Hua, Peter Pavlik, Rebecca Buonpane, Chew-Shun Chang
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Method and device for estimating open circuit voltage of battery based on a gas-liquid dynamic model
Patent number: 11428741Abstract: A method and device for estimating an open circuit voltage of a battery based on a gas-liquid dynamic model, includes the following steps: deriving an undetermined equation for estimating the open circuit voltage according to a gas-liquid dynamic model; identifying the estimation equation parameters according to experimental data; designing a method for estimating the open circuit voltage according to the complete equation for estimating open circuit voltage and calculating to obtain an estimated value of the open circuit voltage. The estimation equation of open circuit voltage includes the battery temperature.Type: GrantFiled: March 29, 2019Date of Patent: August 30, 2022Assignee: JIANGSU UNIVERSITYInventors: Biao Chen, Haobin Jiang, Huayang Sun, Huanhuan Li, Lei Hua -
Patent number: 11341909Abstract: A pixel drive circuit, a drive method thereof and a display device are provided. The pixel drive circuit includes a writing sub-circuit, an amplification sub-circuit, and a drive sub-circuit, writing sub-circuit is configured to transmit a data voltage provided by a signal input terminal to the amplification sub-circuit under control of the scan signal terminal; the amplification sub-circuit is configured to generate an amplification electrical signal according to the data voltage and output the amplification electrical signal to a drive sub-circuit, the drive sub-circuit is configured to obtain the data voltage based on the amplification electrical signal output by the amplification sub-circuit and provide a drive current to a light-emitting device under control of the data voltage, and the light-emitting device is configured to emit light according to the drive current output by the drive sub-circuit.Type: GrantFiled: April 2, 2019Date of Patent: May 24, 2022Assignees: Hefei BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Lei Hua, Jie Ling, Ran Jiang, Xiaohua Lin, Lei Qin
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Patent number: 11307258Abstract: A method and system for estimating open circuit voltage of lithium ion batteries with temperature input, that has the following steps: step 1 the undetermined equation for estimating open circuit voltage with temperature input is derived according to the gas-liquid dynamic model; step 2: the estimation equation parameters are identified according to the experimental data and put into the undetermined equation for estimating open circuit voltage in the step 1 to obtain a complete equation for estimating open circuit voltage; step 3: the method for estimating open circuit voltage with temperature input is designed according to the complete equation for estimating open circuit voltage.Type: GrantFiled: April 30, 2019Date of Patent: April 19, 2022Assignee: JIANGSU UNIVERSITYInventors: Biao Chen, Haobin Jiang, Huayang Sun, Huanhuan Li, Lei Hua
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METHOD AND DEVICE FOR ESTIMATING OPEN CIRCUIT VOLTAGE OF BATTERY BASED ON A GAS-LIQUID DYNAMIC MODEL
Publication number: 20210405119Abstract: A method and device for estimating an open circuit voltage of a battery based on a gas-liquid dynamic model, includes the following steps: deriving an undetermined equation for estimating the open circuit voltage according to a gas-liquid dynamic model; identifying the estimation equation parameters according to experimental data; designing a method for estimating the open circuit voltage according to the complete equation for estimating open circuit voltage and calculating to obtain an estimated value of the open circuit voltage. The estimation equation of open circuit voltage includes the battery temperature.Type: ApplicationFiled: March 29, 2019Publication date: December 30, 2021Inventors: Biao CHEN, Haobin Jiang, Huayang SUN, Huanhuan LI, Lei HUA -
Publication number: 20210383753Abstract: A pixel drive circuit, a drive method thereof and a display device are provided. The pixel drive circuit includes a writing sub-circuit, an amplification sub-circuit, and a drive sub-circuit, writing sub-circuit is configured to transmit a data voltage provided by a signal input terminal to the amplification sub-circuit under control of the scan signal terminal; the amplification sub-circuit is configured to generate an amplification electrical signal according to the data voltage and output the amplification electrical signal to a drive sub-circuit, the drive sub-circuit is configured to obtain the data voltage based on the amplification electrical signal output by the amplification sub-circuit and provide a drive current to a light-emitting device under control of the data voltage, and the light-emitting device is configured to emit light according to the drive current output by the drive sub-circuit.Type: ApplicationFiled: April 2, 2019Publication date: December 9, 2021Applicants: Hefei BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Lei Hua, Jie Ling, Ran Jiang, Xiaohua Lin, Lei Qin
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Publication number: 20210327870Abstract: A semiconductor device includes a voltage input circuit node and a ground voltage node. A first transistor is coupled between the voltage input circuit node and the ground voltage node. A triggering circuit is coupled between the voltage input circuit node and the ground voltage node in parallel with the first transistor. The triggering circuit includes a trigger diode. An output of the triggering circuit is coupled to a control terminal of the first transistor. A load is powered by coupling the load between the voltage input circuit node and the ground voltage node.Type: ApplicationFiled: June 30, 2021Publication date: October 21, 2021Applicant: Semtech CorporationInventors: Lei Hua, William Allen Russell, Changjun Huang, Bo Liang, Pengcheng Han
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Patent number: 11114432Abstract: A semiconductor device includes a voltage input circuit node and a ground voltage node. A first transistor is coupled between the voltage input circuit node and the ground voltage node. A triggering circuit is coupled between the voltage input circuit node and the ground voltage node in parallel with the first transistor. The triggering circuit includes a trigger diode. An output of the triggering circuit is coupled to a control terminal of the first transistor. A load is powered by coupling the load between the voltage input circuit node and the ground voltage node.Type: GrantFiled: March 5, 2019Date of Patent: September 7, 2021Assignee: Semtech CorporationInventors: Lei Hua, William Allen Russell, Changjun Huang, Bo Liang, Pengcheng Han
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Publication number: 20210141019Abstract: A method and system for estimating open circuit voltage of lithium ion batteries with temperature input, that has the following steps: step 1 the undetermined equation for estimating open circuit voltage with temperature input is derived according to the gas-liquid dynamic model; step 2: the estimation equation parameters are identified according to the experimental data and put into the undetermined equation for estimating open circuit voltage in the step 1 to obtain a complete equation for estimating open circuit voltage; step 3: the method for estimating open circuit voltage with temperature input is designed according to the complete equation for estimating open circuit voltage.Type: ApplicationFiled: April 30, 2019Publication date: May 13, 2021Applicant: JIANGSU UNIVERSITYInventors: Biao CHEN, Haobin JIANG, Huayang SUN, Huanhuan LI, Lei HUA
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Publication number: 20200407429Abstract: Antibodies and antigen binding fragments thereof directed against Staphylococcus aureus (S. aureus) surface determinant antigens and secreted toxins are disclosed. Methods of detecting, diagnosing and treating S. aureus using the antibodies and antigen binding fragments thereof are also provided.Type: ApplicationFiled: July 9, 2020Publication date: December 31, 2020Applicant: MedImmune, LLCInventors: Bret SELLMAN, Christine Tkaczyk, Partha S. Chowdhury, Lei Hua, Peter Pavlik, Rebecca Buonpane, Chew-Shun Chang
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Patent number: 10804694Abstract: An embodiment of the present disclosure discloses an over-temperature protection circuitry and a driving method. The circuit includes a source circuit, a comparator circuit and an output circuit, wherein the comparator circuit includes a thermistor, a first resistor and a comparator, the source circuit is connected to a first input terminal of the comparator via the thermistor and is connected to a second input terminal of the comparator via the first resistor; and the comparator circuit is configured to compare a first signal from the first input terminal with a second signal from the second input terminal, and output a control signal according to a comparison result, the control signal is an over-temperature control signal in the case that the comparison result indicates that the temperature is greater than or equal to a protection threshold, and the output circuit is configured to output an disenabling signal.Type: GrantFiled: December 18, 2017Date of Patent: October 13, 2020Assignees: BOE TECHNOLOGY GROUP CO., LTD., HEFEI BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Ran Jiang, Hai Kang, Donghui Wang, Lei Hua, Zhen Tang, Weiwei Pan, Hongxun Zhang
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Patent number: 10759849Abstract: The present invention provides for methods of preventing and/or treating S. aureus-associated bacteremia and sepsis, and methods for preventing and/or treating S. aureus-associated pneumonia in immunocompromised patients using anti-S. aureus alpha-toxin (anti-AT) antibodies. Also provided are methods of reducing S. aureus bacterial load in the bloodstream or heart of a mammalian subject comprising administering to the subject an effective amount of an isolated anti-S. aureus alpha toxin (anti-AT) antibody or antigen-binding fragment thereof. Methods of reducing S. aureus bacterial agglutination and/or thromboembolic lesion formation in a mammalian subject comprising administering to the subject an effective amount of an isolated anti-S. aureus alpha toxin (anti-AT) antibody or antigen-binding fragment thereof, are also provided. Also provided are methods of preventing or reducing the severity of S. aureus associated pneumonia in an immunocompromised mammalian subject.Type: GrantFiled: October 11, 2019Date of Patent: September 1, 2020Assignee: MEDIMMUNE, LLCInventors: Brett R. Sellman, Christine Tkaczyk, Melissa Hamilton, Lei Hua
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Patent number: 10730934Abstract: Antibodies and antigen binding fragments thereof directed against Staphylococcus aureus (S. aureus) surface determinant antigens and secreted toxins are disclosed. Methods of detecting, diagnosing and treating S. aureus using the antibodies and antigen binding fragments thereof are also provided.Type: GrantFiled: January 25, 2018Date of Patent: August 4, 2020Assignee: Medlmmune, LLCInventors: Bret Sellman, Christine Tkaczyk, Partha S. Chowdhury, Lei Hua, Peter Pavlik, Rebecca Buonpane, Chew-Shun Chang
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Patent number: 10706789Abstract: A pixel driving circuit, a driving method thereof, and a display device are provided. According to the pixel driving circuit, a data voltage is provided to a first electrode of a driving transistor; a storage sub-circuit is charged or discharged; a first voltage signal from a first voltage terminal is provided to a control electrode of the driving transistor, and a second voltage signal from a second voltage terminal or a third voltage signal from a third voltage terminal is provided to a first node; the data voltage and a threshold voltage of the driving transistor are written to the control electrode of the driving transistor, to turn on a second electrode of the driving transistor and the third voltage terminal, to control a light-emitting element to emit light.Type: GrantFiled: November 29, 2018Date of Patent: July 7, 2020Assignees: BOE TECHNOLOGY GROUP CO., LTD., HEFEI BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Lei Hua, Jie Ling, Donghui Wang
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Patent number: 10642417Abstract: The present disclosure provides a method and apparatus for determining touching action and a display device. The method comprises the following steps of: determining a first touching region where a variation value of capacitance is larger than or equal to a first preset value during each period of N consecutive periods, in which N?2; and outputting a touching signal according to the first touching region, wherein each period of the N consecutive periods is a scanning period of the touch pane. The embodiment of the present disclosure may scan all of the touching regions of the touch panel during N consecutive scanning periods, and then determine the first touching region has a variation value of capacitance larger than or equal to the first preset value during the N consecutive scanning periods to be a region touched by the user so as to output a touch signal based on the region.Type: GrantFiled: August 3, 2016Date of Patent: May 5, 2020Assignees: BOE TECHNOLOGY GROUP CO., LTD., HEFEI BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Lei Hua, Qing Yang, Hongchao He
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Publication number: 20200109191Abstract: The present invention provides for methods of preventing and/or treating S. aureus-associated bacteremia and sepsis, and methods for preventing and/or treating S. aureus-associated pneumonia in immunocompromised patients using anti-S. aureus alpha-toxin (anti-AT) antibodies. Also provided are methods of reducing S. aureus bacterial load in the bloodstream or heart of a mammalian subject comprising administering to the subject an effective amount of an isolated anti-S. aureus alpha toxin (anti-AT) antibody or antigen-binding fragment thereof. Methods of reducing S. aureus bacterial agglutination and/or thromboembolic lesion formation in a mammalian subject comprising administering to the subject an effective amount of an isolated anti-S. aureus alpha toxin (anti-AT) antibody or antigen-binding fragment thereof, are also provided. Also provided are methods of preventing or reducing the severity of S. aureus associated pneumonia in an immunocompromised mammalian subject.Type: ApplicationFiled: October 11, 2019Publication date: April 9, 2020Applicant: MedImmune, LLCInventors: Brett R. SELLMAN, Christine TKACZYK, Melissa HAMILTON, Lei HUA