Patents by Inventor Lei Jin
Lei Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12366950Abstract: Provided are an interaction method and apparatus, an electronic device, and a storage medium. The method includes displaying a target page, where target content containing a target object is displayed in the target page; receiving a shake trigger operation of a user; and in response to the shake trigger operation, displaying associated content of the target content in a layer above the target page and displaying the detail page of the target object after completing displaying the associated content.Type: GrantFiled: July 27, 2023Date of Patent: July 22, 2025Assignee: Beijing Zitiao Network Technology Co., Ltd.Inventors: Han Xu, Mengqi Wu, Xiaolei Shi, Xu Zhong, Huan Wang, Shuo Wang, Ji Liu, Zhiquan Zhang, Zhiyong Luo, Jia Liu, Chengkai Peng, Yongkang Chen, Ziqi Liu, Jialong Zhao, Yirui Cao, Lei Jin
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Patent number: 12344669Abstract: An anti-CD47 monoclonal antibody and use thereof. The provided anti-CD47 monoclonal antibody can effectively inhibit tumor growth. Blocking human SIRP and human CD47 signals may enhance macrophage phagocytosis of tumor cells, prevent the tumor cells from escaping a tumor immune defense system, and have an anti-tumor function. Blocking association between the CD47 on a tumor cell surface and the SIRP on a macrophage surface may block a “do not eat me” signal from the tumor cells, promoting tumor cell recognition and uptake of macrophages, and thereby facilitating tumor cells to be phagocytosed. The association between the CD47 on a tumor cell surface and the SIRP on a macrophage surface is a common “do not eat me” signal. The anti-CD47 antibody, as a very promising target in the tumor immune system, will play a powerful and effective role in human cancer therapy.Type: GrantFiled: September 30, 2021Date of Patent: July 1, 2025Assignee: CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD.Inventors: Xiao Feng, Lei Jin, Liang Xiao, Tao Wang, Suofu Qin
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Publication number: 20250186201Abstract: An interventional aortic valve includes a stent and three fan-shaped valve leaflets on an inner side of the stent. The stent is a metal mesh tube with three connecting posts, and is radially compressible and in a flaring shape after being expanded by a balloon. Each of the fan-shaped valve leaflets has a free edge, an arc-shaped bottom edge opposite the free edge, and valve leaflet junction connecting parts extending on two sides of the valve leaflet. Three connecting posts are uniformly distributed on the metal mesh tube. Each valve leaflet junction connecting part is folded twice to form a cushioning portion in which a tip of each of the valve leaflet junction connecting part is folded inside the cushioning portion. Each cushioning portion is fixed by sutures which extend in a direction perpendicular to a radial direction of the metal mesh tube. Adjacent cushioning portions of every two adjacent valve leaflets are sutured to one of the connecting posts.Type: ApplicationFiled: February 20, 2025Publication date: June 12, 2025Inventors: Lei JIN, Hong MU, Zhihao FAN
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Publication number: 20250161031Abstract: The present invention discloses a presettable artificial biological aortic valve which comprises a valve seat (1), a valve leaflet stent (2) and three valve leaflets (3), wherein the valve seat (1) is a one-way limiting expandable annular metal seat; the head end of each seat body unit (4) is sequentially provided with a first rivet (7), a limiting protrusion (6) and a first long circular groove (5) from the outside to the inside; the tail end of each seat body unit (4) is sequentially provided with a second long circular groove (8), a second limiting hole (10) and a first limiting hole (9) matched with the limiting protrusion (6), and a second rivet (11) matched with the first long circular groove (5). The presettable artificial biological aortic valve has an original preset state and a normal use state after one-way limiting expansion.Type: ApplicationFiled: February 15, 2023Publication date: May 22, 2025Applicant: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD.Inventors: Lei JIN, Chengxiong GU, Jiangang WANG, Zhihao FAN, Tiegang LIU, Jia WU
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Publication number: 20250143872Abstract: The present invention discloses a one-way limiting expandable artificial heart valve which comprises a valve seat (1), a valve leaflet stent (2) and three valve leaflets (3) wherein the valve seat (1) comprises a one-way limiting expandable annular metal seat (4), the annular metal seat (4) is composed of three sections of seat body units (5), the head end of each section of seat body unit (5) is sequentially provided with a first rivet (8), a limiting protrusion (7) and a first long circular groove (6), the tail end of each section of seat body unit (5) is sequentially provided with a second long circular groove (9), a second limiting hole (11) and a first limiting hole (10), and a second rivet (12), and the artificial heart valve has a normal use original state and a one-way limiting expansion state.Type: ApplicationFiled: February 15, 2023Publication date: May 8, 2025Applicants: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD., WEST CHINA HOSPITAL OF SICHUAN UNIVERSITYInventors: Lei JIN, Yingqiang GUO, Zhihao FAN, Tiegang LIU, Jia WU
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Publication number: 20250140329Abstract: Upon determining that a first read operation on one memory cell of memory cells has failed, a second read operation on the memory cell is started. In the second read operation, a second pass voltage is applied to second word line, and a first pass voltage is applied to third word line. The second word line include one or more word lines adjacent to a selected word line, and the third word line include remaining unselected word lines. The selected word line corresponds to the memory cell to be read. The first pass voltage includes a voltage applied to the second word line in the first read operation. The second pass voltage is higher than the first pass voltage.Type: ApplicationFiled: January 6, 2025Publication date: May 1, 2025Inventors: Hongtao Liu, Lei Jin, Xiangnan Zhao, Ying Huang, Lei Guan, Yuanyuan Min
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Patent number: 12285335Abstract: A split type precisely-anchorable transcatheter aortic valve system comprises a split transcatheter aortic valve anchoring stent (10) and a transcatheter artificial biological aortic valve (20), wherein the shape and structure of the transcatheter aortic valve anchoring stent (10) are matched with the real structure of the aortic valve after the patient's image data is subjected to three-dimensional reconstruction, the transcatheter aortic valve anchoring stent (10) is delivered to the aortic valve position of the patient to be released, deformed and combined with the aortic valve leaflet tissue and the subvalvular tissue of the patient; the transcatheter artificial biological aortic valve (20) is delivered into the transcatheter aortic valve anchoring stent (10) to be released, the valve stent is deformed to expand the valve to the functional state, the transcatheter aortic valve anchoring stent (10) is deformed again and combined with the expanded transcatheter artificial biological aortic valve (20), and mType: GrantFiled: November 17, 2022Date of Patent: April 29, 2025Assignee: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD.Inventors: Lei Jin, Xiangbin Pan, Jia Wu, Liyan Li, Zhihao Fan, Kangjian Wu
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Patent number: 12268594Abstract: A split type precisely-anchorable transcatheter mitral valve system comprises a split transcatheter mitral valve anchoring stent (10) and a transcatheter artificial biological mitral valve (20), wherein the shape and structure of the transcatheter mitral valve anchoring stent (10) are matched with the mitral valve real structure after the patient image data is subjected to three-dimensional reconstruction, the transcatheter mitral valve anchoring stent (10) is firstly delivered to the mitral valve position of the patient to be released and deformed, and the transcatheter artificial biological mitral valve (20) is in personalized precise alignment and coaptation with tissues on the mitral valve position of the patient and under the petals; the transcatheter artificial biological mitral valve (20) is delivered into the transcatheter mitral valve anchoring stent (10) to be released, the transcatheter artificial biological mitral valve (20) is released and deformed and expanded to a functional state, the transcatType: GrantFiled: November 17, 2022Date of Patent: April 8, 2025Assignees: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD., WEST CHINA HOSPITAL OF SICHUAN UNIVERSITYInventors: Lei Jin, Yingqiang Guo, Jia Wu, Liyan Li, Hong Mu, Kangjian Wu, Zhihao Fan
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Publication number: 20250107888Abstract: A split type precisely-anchorable transcatheter valve-in-ring system comprises a split transcatheter valve-in-ring anchoring stent (10) and a transcatheter artificial biological valve-in-ring (20), wherein the shape and structure of the transcatheter valve-in-ring anchoring stent (10) are matched with the real structure of the annuloplasty ring and supravalvular and infravalvular tissues after three-dimensional reconstruction based on imaging data of a patient who have undergone valve failure after implantation of a annuloplasty ring (30), the transcatheter valve-in-ring anchoring stent (10) is firstly delivered to the patient's failed annuloplasty ring for release, deformation and alignment with the supravalvular and infravalvular tissues of the failed annuloplasty ring; the transcatheter artificial biological valve-in-ring (20) is delivered to the transcatheter valve-in-ring anchoring stent (10) for release, the stent of the transcatheter artificial biological valve-in-ring (20) deforms and expands to the fType: ApplicationFiled: November 17, 2022Publication date: April 3, 2025Applicant: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD.Inventors: Lei JIN, Lai WEI, Kangjian WU, Jia WU, Zhihao FAN, Liyan LI
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Patent number: 12258386Abstract: Provided are a humanized anti-A? monoclonal antibody and use thereof. The humanized anti-A? monoclonal antibody provided can inhibit the polymerization of A? monomers, protect nerve cells from the toxicity of A?, and have a certain effect on improving the cognitive learning and memory ability of Alzheimer's dementia model mice, and can be used for the treatment and diagnosis of diseases and disorders related to amyloidosis, such as Alzheimer's disease.Type: GrantFiled: January 17, 2020Date of Patent: March 25, 2025Assignee: Changchun Genescience Pharmaceutical Co., Ltd.Inventors: Xiao Feng, Yangqiu Liang, Lei Jin, Dawei Sun, Tao Wang, Liang Xiao, Shuang Liu, Yuheng Chen, Zhengyi Li
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Publication number: 20250092557Abstract: An aluminum containing component comprises an aluminum alloy and an aluminum oxide layer disposed on the aluminum alloy. The aluminum oxide layer comprises crystalline aluminum oxide. The aluminum containing component is at least one of vane, a fan blade or a fan casing of a low pressure compressor section of a gas turbine. In an embodiment, a method comprises disposing an aluminum containing component in an electrochemical cell that comprises a dilute alkaline solution. The aluminum containing component is electrically contacted to become a first electrode in the electrochemical cell. The wall of the bath is electrically contacted to act as a second electrode in the electrochemical cell. A voltage is applied between the first electrode and the second electrode to form an aluminum oxide layer on the aluminum containing component.Type: ApplicationFiled: September 6, 2024Publication date: March 20, 2025Inventors: Lei Jin, Ryan Matthew Brodeur
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Publication number: 20250069673Abstract: According to one aspect, a method of operating a memory is provided. The method may include applying a first power supply voltage to a common source during a program precharge process. The method may include applying a first voltage to a first bottom gate line and applying a second voltage to a second bottom gate line starting at a first moment of the program precharge process. The method may include applying a second power supply voltage to the first bottom gate line and applying a third voltage to the second bottom gate line after the first moment of the program precharge process.Type: ApplicationFiled: December 15, 2023Publication date: February 27, 2025Inventors: Junbao Wang, Jianquan Jia, Yuanyuan Min, Xiangnan Zhao, Ying Cui, Kaikai You, Jiameng Cui, Lei Guan, Chenhui Li, An Zhang, Lei Jin
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Publication number: 20250068558Abstract: The present disclosure provides a method for operating a memory, a memory and a memory system, and relates to the technical field of semiconductor chip. The method includes: during the erase phase, applying an erase voltage to the word line, and applying an erase voltage to the select line coupled to a target select gate; during the program phase for select gate, applying a pass voltage to the word line, and applying a program voltage to the select line coupled to the target select gate.Type: ApplicationFiled: December 4, 2023Publication date: February 27, 2025Inventors: Jianquan JIA, XiangNan ZHAO, Yuanyuan MIN, Ying CUI, Kaikai YOU, Chenhui LI, Wei QI, Jiameng CUI, Lei GUAN, Junbao WANG, Lei JIN
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Publication number: 20250069662Abstract: The present disclosure provides a memory device, a memory system, and an operation method of a memory device, and relates to the technical field of semiconductor chips. The memory device includes a memory cell array including a source layer, a bottom select gate layer, and a gate layer, and the bottom select gate layer is located between the source layer and the gate layer, wherein the bottom select gate layer includes a plurality of bottom select gates, and a bottom select gate of a first memory string and a bottom select gate of a second memory string are connected with a same select line; and a peripheral circuit coupled to the memory cell array, wherein the peripheral circuit is configured to apply a selection voltage to the select line to control the first memory string and the second memory string.Type: ApplicationFiled: December 18, 2023Publication date: February 27, 2025Inventors: Jianquan JIA, XiangNan ZHAO, Feng XU, Yuanyuan MIN, Ying CUI, Chenhui LI, Wei QI, Junbao WANG, Lei JIN
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Publication number: 20250058144Abstract: Disclosed are a negative-pressure drug loading apparatus and a negative-pressure drug loading method. When the apparatus is in use, drug particles to be loaded are placed into the particle storage tube, and a proper amount of drug solution is introduced. The particle storage tube is placed in the body, and the sealing space is sealed. A vacuum pump is used to execute a negative pressure operation in the body until the inside of the particle storage tube is pumped into a vacuum. An air valve of the vacuum pump is opened, such that the drug solution comes into the said particles under the action of pressure. After the pressure is stable, the particle storage tube is let stand for a period of time such that the drug solution stably stays in the said particles.Type: ApplicationFiled: September 2, 2024Publication date: February 20, 2025Applicant: SUZHOU YIBEN LIFE TECHNOLOGY CO., LTDInventors: Guoxiang SUN, Yonghua DONG, Liangliang ZHAO, Lei JIN
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Patent number: 12230342Abstract: Upon determining that a first read operation on one memory cell of a plurality of memory cells has failed, a second read operation on the memory cell is started. In the second read operation, a second pass voltage is applied to first unselected word lines, and a first pass voltage is applied to second unselected word lines. The first unselected word lines include one or more word lines adjacent to a selected word line, and the second unselected word lines include remaining unselected word lines. The selected word line corresponds to the memory cell to be read. The first pass voltage includes a voltage applied to the first unselected word lines in the first read operation. The second pass voltage is higher than the first pass voltage.Type: GrantFiled: July 22, 2022Date of Patent: February 18, 2025Assignee: YANGTZE MEMORY TECHNOLOGIES CO., LTD.Inventors: Hongtao Liu, Lei Jin, Xiangnan Zhao, Ying Huang, Lei Guan, Yuanyuan Min
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Publication number: 20250041057Abstract: The split type precisely-anchorable transcatheter tricuspid valve system comprises a split transcatheter tricuspid valve anchoring stent (10) and a transcatheter artificial biological tricuspid valve (20), wherein the shape and structure of the transcatheter tricuspid valve anchoring stent (10) are matched with the tricuspid valve real structure after the patient's image data is subjected to three-dimensional reconstruction, the transcatheter tricuspid valve anchoring stent (10) is firstly delivered to the tricuspid valve site of the patient to be released, deformed and personalized and precise alignment with a supravalvular (40) and subvalvular (50) tissue of the patient's tricuspid valve site; the transcatheter artificial biological tricuspid valve (20) is delivered into the transcatheter tricuspid valve anchoring stent (10) to be released, and the transcatheter artificial biological tricuspid valve (20) is released and deformed and expanded to a functional state, the transcatheter tricuspid valve anchoringType: ApplicationFiled: November 17, 2022Publication date: February 6, 2025Applicant: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD.Inventors: Lei JIN, Huanlei HUANG, Zhenzhong WANG, Liyan LI, Zhihao FAN, Hong MU, Jia WU, Kangjian WU
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Publication number: 20250032252Abstract: A split type precisely-anchorable transcatheter aortic valve system comprises a split transcatheter aortic valve anchoring stent (10) and a transcatheter artificial biological aortic valve (20), wherein the shape and structure of the transcatheter aortic valve anchoring stent (10) are matched with the real structure of the aortic valve after the patient's image data is subjected to three-dimensional reconstruction, the transcatheter aortic valve anchoring stent (10) is delivered to the aortic valve position of the patient to be released, deformed and combined with the aortic valve leaflet tissue and the subvalvular tissue of the patient; the transcatheter artificial biological aortic valve (20) is delivered into the transcatheter aortic valve anchoring stent (10) to be released, the valve stent is deformed to expand the valve to the functional state, the transcatheter aortic valve anchoring stent (10) is deformed again and combined with the expanded transcatheter artificial biological aortic valve (20), and mType: ApplicationFiled: November 17, 2022Publication date: January 30, 2025Applicant: BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD.Inventors: Lei JIN, Xiangbin PAN, Jia WU, Liyan LI, Zhihao FAN, Kangjian WU
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Publication number: 20250029660Abstract: The disclosure provides a programming method of a memory, a memory and a memory system, which relate to the technical field of semiconductor chips. The programming method comprises: applying a program voltage to a first word line coupled to a plurality of memory cells of a first memory cell slice and a plurality of memory cells of a second memory cell slice; and during a stage of applying the program voltage to the first word line, applying a turn-on voltage to a first select line and a second select line sequentially, wherein the first select line is coupled to a select transistor of the first memory cell slice, and the second select line is coupled to a select transistor of the second memory cell slice.Type: ApplicationFiled: December 4, 2023Publication date: January 23, 2025Inventors: Jianquan JIA, Junbao WANG, Hongtao LIU, Lei JIN
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Publication number: 20250022519Abstract: The present application discloses a memory, a memory system, and a method for operating memory, which belongs to the memory techniques field. The method for operating memory comprises determining a storage state of a reference memory cell, determining a discharge duration of a sensing node corresponding to a target memory cell based on the storage state of the reference memory cell, and reading the target memory cell based on the discharge duration of the sensing node corresponding to the target memory cell to obtain read results. The target memory cell and the reference memory cell are located in the same string and are adjacent, and the programming order of the reference memory cell is after that of the target memory cell. The present application may reduce the influence on reading memory cells by interlayer interference and improve the accuracy of reading memory cells.Type: ApplicationFiled: December 4, 2023Publication date: January 16, 2025Inventors: Xiangnan ZHAO, Hongtao LIU, Chenhui LI, Lei JIN, Hua TAN