Publication number: 20240228501
Abstract: A compound represented by formula (I), or a stereoisomer, a tautomer, an isotope-labeled form, a nitrogen oxide, a solvate, a polymorph, a pharmaceutically acceptable salt, or a prodrug thereof, a method for preparing the same, and a pharmaceutical composition comprising the same are provided. The compound is a NK-3 receptor antagonist, and may be used for preventing and/or treating depression, anxiety disorder, psychosis, schizophrenia, psychotic disorder, bipolar disorder, cognitive disorder, Parkinson's disease, Alzheimer's disease, attention deficit hyperactivity disorder, pain, convulsion, obesity, inflammatory disease, vomiting, preeclampsia, airway-related disease, reproductive disorder, contraception and sex hormone-dependent disease, gynecological disease-related disease, or menopausal syndrome-related disease.
Type:
Application
Filed:
April 20, 2022
Publication date:
July 11, 2024
Inventors:
Yunlong SONG, Guangyuan SHEN, Peng LIU, Manhua LI, Lei JIN, Guocheng WANG, Xinyuan MIAO, Yue HUANG