Patents by Inventor Lei Johnson

Lei Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR ALTERING COMPLEMENT ACTIVATION
    Publication number: 20260258407
    Abstract: Compositions and methods for reducing complement activation by introducing one or more alterations into a complement factor B (CFB) polynucleotide in a cell. In particular embodiments, the invention of the disclosure features a base editor system (e.g., a fusion protein or complex comprising a programmable DNA binding protein, a nucleobase editor, and gRNA) for modifying a CFB polynucleotide, where the modification is associated with reduced expression, and/or reduced activity of the CFB polypeptide encoded by the polynucleotide.
    Type: Application
    Filed: May 14, 2026
    Publication date: September 3, 2026
    Applicant: Beam Therapeutics Inc.
    Inventors: Lei Johnson, Tanggis Bohnuud, Lo-I Cheng, Michael Packer, Brian Cafferty