Abstract: An automatic generation method for three-dimensional morphology of ruts in asphalt pavements comprises: constructing a standard rut cross-section representation model, classifying ruts, acquiring detection data of a rutted section of an asphalt pavement, selecting different rut cross-sections at equal intervals in a longitudinal direction of the pavement, denoising and smoothening the rut cross-sections, selecting feature points according to geometric fluctuation features of the rut cross-sections, connecting the feature points and fitting a cross-sectional curve based on an evolution law of rut deformation, and fusing multiple reconstructed rut cross-sections to realize automatic generation and visualization of three-dimensional morphology of a rut.

Abstract: A semiconductor device having a ring-shaped cell region, a first termination region and a second termination region. The cell region includes a first base region, a source region in the first base region, first and second gate trench structures. The first base region and the source region are sandwiched by the first and second gate trench structure in a plane. The first termination region is surrounded by the ring-shaped cell region in the plane. The second termination region surrounds the ring-shaped cell region in the plane. The first termination region has a round-shaped source trench structure including a source electrode filling in a source trench with a source dielectric layer in between for insulation. The second termination region has a ring-shaped first source trench structure including a source electrode filling in a source trench with a source dielectric layer in between for insulation.

Abstract: An automatic generation method for three-dimensional morphology of ruts in asphalt pavements comprises: constructing a standard rut cross-section representation model, classifying ruts, acquiring detection data of a rutted section of an asphalt pavement, selecting different rut cross-sections at equal intervals in a longitudinal direction of the pavement, denoising and smoothening the rut cross-sections, selecting feature points according to geometric fluctuation features of the rut cross-sections, connecting the feature points and fitting a cross-sectional curve based on an evolution law of rut deformation, and fusing multiple reconstructed rut cross-sections to realize automatic generation and visualization of three-dimensional morphology of a rut.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: Disclosed is a filtering device. The device includes a main body part and a filter element assembly, where the main body part has a mounting cavity for accommodating the filter element assembly, further includes a base and a screen cover arranged as a cover of the base, and at least one rack for fixing the filter element assembly is disposed on an inner wall of the screen cover and/or the base; and the filter element assembly includes a folded filter element arranged in a folded shape, and a rubber strip arranged on the folded filter element for maintaining the shape of the folded filter element to facilitate quick assembly and disassembly of the folded filter element. Further, the screen cover and the base are connected through various snap-fit assemblies, without requiring additional connecting members for fixing them, which is convenient for disassembly and assembly, and has a simple structure.

Abstract: A conjugate and preparation method therefor, comprising a medication composition comprising the conjugate and a use of the medication composition in preparing medications for the treatment or prevention of diseases.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: A touch operation method applied to an electronic device having a curved screen, where the curved screen includes a side edge of the electronic device. After detecting that the side edge is touched, the electronic device determines a target region, where the target region is a contact region of a user on the side edge in a holding mode. The electronic device prompts a location of the target region. After detecting a touch operation performed by the user on the target region, the electronic device performs a corresponding response operation for the touch operation.

Abstract: The present invention provided an oligonucleotide targeting the core editing-site complementary sequence (ECS) of AZIN1 gene, wherein the core ECS of AZIN1 gene comprises the sequence 5?-GCTTTTCC-3?, and wherein the oligonucleotide comprises one or more nucleotides with sugar modification and one or more modified internucleotide linkages. In another aspect, there is provided a pharmaceutical composition comprising the oligonucleotide as disclosed herein. In another aspect, there is provided a method of inhibiting AZIN1 pre-mRNA editing in a cell, wherein the AZIN1 pre-mRNA editing is mediated by adenosine deaminase acting on RNA-1 (ADAR-1), as well as a method of using the same for the treatment of cancers associated with AZIN1 pre-mRNA editing, including liver cancer.

Abstract: A mobile quantitative feeding-spraying integrated system and method. The system includes at least one hull equipped with a propeller, a feeder housing fixedly arranged on the hull, a feed box arranged on the feeder housing, a flip assembly provided at an upper end of the feed box, a blanking device arranged in the feeder housing to quantitatively control the bait blanking amount, a casting device and a spraying device. An upper end of the blanking device is a feeding end, which supports and is connected to the lower end of the feed box. A lower end of the blanking device is the discharging end. An upper side of the casting device is connected with the lower end of the blanking device, and the lower side of the casting device is provided with a discharging end facing the aquaculture water body.

Abstract: A TEM electromechanical in-situ testing method of one-dimensional materials is provided. A multi-function sample stage which can compress, buckle and bend samples is designed and manufactured. A carbon film on a TEM grid of Cu is eliminated, and the TEM grid of Cu is cut in half through the center of the circle. The samples are dispersed ultrasonically in alcohol and dropped on the edge of the semicircular grid of Cu with a pipette. A single sample is fixed on the edge of a substrate of the sample stage with conductive silver epoxy by using a micromechanical device under an optical microscope, and conductive silver paint is applied to the surface of the substrate of the sample stage; and an electromechanical in-situ testing is conducted in a TEM. This provides a simple and efficient sample preparation and testing method for a TEM electromechanical in-situ observing experiment.

Abstract: A mobile quantitative feeding-spraying integrated system and method. The system includes at least one hull equipped with a propeller, a feeder housing fixedly arranged on the hull, a feed box arranged on the feeder housing, a flip assembly provided at an upper end of the feed box, a blanking device arranged in the feeder housing to quantitatively control the bait blanking amount, a casting device and a spraying device. An upper end of the blanking device is a feeding end, which supports and is connected to the lower end of the feed box. A lower end of the blanking device is the discharging end. An upper side of the casting device is connected with the lower end of the blanking device, and the lower side of the casting device is provided with a discharging end facing the aquaculture water body.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: A conjugate and preparation method therefor, comprising a medication composition comprising the conjugate and a use of the medication composition in preparing medications for the treatment or prevention of diseases.

Abstract: The present invention provides a self-healing method for fractured SiC amorphous nanowires. A goat hair in a Chinese brush pen of goat hair moves and transfers single crystal nanowires under an optical microscope. On an in-situ nanomechanical test system of a TEM, local single crystal nanowires are irradiated with an electron beam for conducting amorphization transformation. Amorphous length of a single crystal after transformation is 60-100 nm. A fracture strength test is conducted on the amorphous nanowires in the single crystal after transformation in the TEM; and fracture strength of the amorphous nanowires is 9-11 GPa. After the amorphous nanowires are fractured, unloading causes a slight contact between the fractured end surfaces; and self-healing of the nanowires is conducted after waiting for 16-25 min in a vacuum chamber of the TEM. Atom diffusion is found at a healed fracture through in-situ TEM representation; and recrystallization is found in the amorphous nanowires.

Abstract: A TEM electromechanical in-situ testing method of one-dimensional materials is provided. A multi-function sample stage which can compress, buckle and bend samples is designed and manufactured. A carbon film on a TEM grid of Cu is eliminated, and the TEM grid of Cu is cut in half through the center of the circle. The samples are dispersed ultrasonically in alcohol and dropped on the edge of the semicircular grid of Cu with a pipette. A single sample is fixed on the edge of a substrate of the sample stage with conductive silver epoxy by using a micromechanical device under an optical microscope, and conductive silver paint is applied to the surface of the substrate of the sample stage; and an electromechanical in-situ testing is conducted in a TEM. This provides a simple and efficient sample preparation and testing method for a TEM electromechanical in-situ observing experiment.