Abstract: Provided in the present invention are a compound as shown in formula I, various crystal forms thereof, a hydrate, a solvate or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition. The compound of the present invention can effectively treat Alzheimer's disease or Down's syndrome, especially cognitive function impairment caused by Alzheimer's disease or Down's syndrome. Also disclosed in the present invention is use of a ubiquitin specific protease USP25 encoded and expressed by chromosome 21 for preventing, treating or ameliorating Alzheimer's disease or Down's syndrome.

Abstract: The invention discloses a sucking particle for heat-not-bum cigarettes, which comprises the following components by weight fraction: 8-20 parts of microcrystalline cellulose, 50-80 parts of tobacco powder, 0.5-2 parts of tobacco pyrolysate, 1 part of physiological taste adjusting component of tobacco, 8-30 parts of atomizing agent, 0.1-2 parts of tobacco essence and 1-10 parts of propylene glycol; the present invention further provides a manufacturing method for the above product. The product has the benefits of good heating performance, rapid atomizing when heated at 250-310° C. with a heating sheet, complete heating and considerable smoke, similar tobacco aroma and physiological satisfaction as smoking traditional cigarettes and less processing difficulty.

Abstract: A strain-sensing device includes a flexible printed circuit and a strain sensor formed on the flexible printed circuit. The flexible printed circuit includes a stacked set of layers. Each layer in the stacked set of layers has a glass transition temperature (Tg) greater than 50 degrees Celsius (50° C.), and each pair of adjacent layers in the stacked set of layers has a Tg greater than 50° C. The stacked set of layers, as a whole, also has a Tg greater than 50° C.

Abstract: One or more processors of a computing device may receive image data obtained via an image sensor of a camera. The one or more processors may apply one or more horizontal filters to the image data to generate horizontally filtered image data and may apply one or more vertical filters to the image data to generate vertically filtered image data. The one or more processors may generate a first accumulation matrix for the horizontally filtered image data and may generate a second accumulation matrix for the vertically filtered image data. The one or more processors may determine autofocus statistics based on the first accumulation matrix and the second accumulation matrix and may output information to adjust one or more lenses of the camera based on the autofocus statistics.

Abstract: A heating component includes: a heating element; and a pipe body. The heating element includes a heating main body that generates infrared light in a powered-on state. The heating main body is arranged in a hollowed-out cylindrical shape and is spaced apart from the pipe body. The pipe body allows the infrared light to pass through. A transmittance of the pipe body to infrared light at wavelengths of 2-4.75 ?m is more than or equal to 50%.

Abstract: A heating structure includes: a tube body having a cavity and a pipe wall transparent to infrared light; and a heating element at least partially arranged in the cavity, at least partially spaced apart from the pipe wall, and that radiates infrared light to pass through the tube body so as to heat an aerosol-generating substrate. The heating element has a first dimension in a transverse direction. The cavity has a second dimension in the transverse direction. A ratio of the first dimension to the second dimension is greater than or equal to 0.65 and less than 1.

Abstract: An aerosol generating device includes a heating element for generating infrared light; a housing having a housing wall that allows the infrared light to pass through, the heating element and the housing wall being at least partially spaced apart; a first temperature obtaining unit that obtains the housing wall temperature of the housing wall; a second temperature obtaining unit that obtains the heating element temperature of the heating element; and a control unit that: outputs a target control temperature based on a preset temperature and the housing wall temperature, processes the heating element temperature and the target control temperature using a preset algorithm, and adjusts power supplying of the heating element.

Abstract: A heating structure includes: a heating element configured that generates infrared light in a power-on state; and a tube body that allows the infrared light to penetrate through. The heating element is at least partially accommodated in the tube body, and a gap is at least partially formed between the heating element and an inner wall of the tube body. An included angle formed between a central axis of the heating element along a length direction of the heating element and a central axis of the tube body along the length direction of the tube body is less than or equal to 5°.

Abstract: A heating structure includes: a heating element for generating infrared light in a power-on state; a tube body that allows the infrared light to penetrate through; and a thermal resistance temperature measuring element. The heating element is at least partially accommodated in the tube body. The thermal resistance temperature measuring element comprises a first temperature measuring segment and a second temperature measuring segment that are provided on a peripheral surface of the tube body, the first temperature measuring segment and the second temperature measuring segment being connected so as to form a temperature measuring loop. The peripheral surface of the tube body includes a plurality of temperature zones along an axial direction of the tube body. A resistance of the first temperature measuring segment is greater than a resistance of the second temperature measuring segment. The first temperature measuring segment is provided corresponding to one temperature zone.

Abstract: A heating component includes: an infrared light transmitting pipe body; and a heating member for generating infrared light. The infrared light transmitting pipe body includes an opening, and the heating member is disposed in the infrared light transmitting pipe body and at least partially spaced apart from a pipe wall of the infrared light transmitting pipe body. The heating component also includes a temperature sensing member having a temperature sensing probe disposed between the heating member and the opening.

Abstract: A heating structure includes: a heating component; a tube body; and a mounting member. The tube body is provided with a tube opening. The mounting member is assembled with an end of the tube body provided with the tube opening. The heating component includes a heating portion and a conductive portion. The heating portion is arranged in the tube body and is at least partially spaced apart from a tube wall of the tube body so as to radiate infrared light through the tube body to heat an aerosol-generating substrate. The conductive portion penetrates through the mounting member and is connected to the heating portion so as to fix the heating component to the mounting member.

Abstract: A heating control method for a heat-not-burn device that includes a heating element for heating an aerosol-forming substrate includes: controlling the heating element so as to increase from an initial temperature to a first temperature when heating is started, and maintaining the first temperature; controlling the heating element so as to increase from a current temperature to a second temperature when detecting a puffing action, the second temperature being greater than the first temperature; and controlling the heating element so as to decrease from a current temperature to a third temperature when detecting that the puffing action ends, the third temperature being less than the second temperature.

Abstract: A heating control method for a heat-not-burn device that includes a heating element and a temperature measurement module includes: performing heating control on the heating element in a power control mode in a preheat stage so as to preheat an aerosol-forming substrate; and obtaining, in a heating stage subsequent to the preheating stage, a temperature detected by the temperature measurement module, and performing heating control on the heating element in a temperature control mode so as to cause a temperature of the heating element to maintain at a preset heat preserving temperature.

Abstract: A method for cleaning an aerosol-generating device having a heating structure for heating an aerosol-forming substrate at an operating temperature includes: monitoring whether the aerosol-forming substrate is inserted into or extracted from the aerosol-generating device; and when the aerosol-forming substrate is extracted, setting a temperature of the heating structure to a self-cleaning temperature not exceeding the operating temperature so as to heat and release a material adhered to or deposited on the heating structure.

Abstract: A heating structure includes: a heating element; and a tube body. The heating element and a tube wall of the tube body are at least partially spaced apart. The heating element is electrically heated and radiates infrared light to transmit through the tube body and heats an aerosol-generating substrate. The tube body includes a first portion and a second portion that are distributed along an axial direction of the tube body. The first portion reaches a higher temperature than a temperature than the second portion when the heating element is energized.

Abstract: A temperature control method applied to an aerosol generating device that includes a heating element and a housing, the heating element being powered on and heated up to generate infrared light to heat an aerosol generating substrate, the heating element and the housing being at least partially spaced apart, the infrared light capable of passing through the housing, the method including: obtaining a temperature signal of the housing; generating an adjustment signal by using a preset algorithm based on the temperature signal and a target temperature; and controlling a heating power of the heating element based on the adjustment signal so as to adjust a temperature of the heating element.

Abstract: A guiding and positioning device for assisting in computed tomography-guided needle biopsy (CT-GNB) includes a control mechanism and an actuating mechanism, where the actuating mechanism includes a base and a support frame; one of the two head ends of the support frame is provided with a locking mechanism; a positioning apparatus includes a first guide rail in an arc shape, and the first guide rail is slidably provided with a guiding apparatus configured to guide different puncture angles in a same plane; the guiding apparatus includes a deflection drive mechanism slidable along the first guide rail, and a first translation mechanism and a second translation mechanism that are arranged perpendicular to each other; and the second translation mechanism is slidably provided with a guiding mechanism configured to guide a puncture through a visible laser space.

Abstract: A method for improving agronomic traits of plants and the use thereof are provided. By means of overexpressing functional gene ZmSPL12 in plants, the salt stress resistance, alkali stress resistance and/or resistance to low nitrogen of plants are improved. The method and the use thereof provide the possibility for cultivating new salt-alkali resistant, and low-nitrogen resistant crop varieties, especially new com varieties, and are of great significance for global grain safety and agricultural sustainable development.

Abstract: The present disclosure discloses a large single-crystal semiconducting graphene directly grown on the silicon face of a silicon carbide substrate and its preparation method, a semiconducting graphene-quasi-free standing graphene all-carbon structure and its preparation method, an ultra-large single-crystal quasi-free standing graphene and its preparation method; the semiconducting graphene is single-layered, uniformly grown, with crystal domain widths reaching up to 500 micrometers and lengths on the order of sub-millimeters, the room temperature mobility of the semiconducting graphene is capable of reaching 5000 cm2/(V·s). The semiconducting graphene can be direct prepared on an insulating substrate.

Abstract: This application provides a signal transmission method and a related device. According to the signal transmission method, when two contact points on an electronic device are respectively in contact with two contact points on a keyboard, the electronic device may transmit a power signal and a GND signal to the keyboard through the contact points that are in contact with each other, that is, the electronic device may supply power to the keyboard. In addition, when a user presses a key on the keyboard to perform input, the keyboard may transmit key position information to the electronic device through a contact point that is in contact with the electronic device. In this signal transmission method, no Bluetooth chip needs to be built into the electronic device and the keyboard, reducing device costs.