Abstract: Provided is a nerve growth factor mutant, wherein the nerve growth factor mutant is an amino acid sequence as shown by any one of SEQ ID No: 3 to SEQ ID No: 21 in the sequence listing. The advantage of the nerve growth factor mutant lies in that the mutation of a nerve growth factor can alleviate side effects such as pain, falling within the field of biological pharmacy.

Abstract: The present application discloses a processing method, apparatus, device, medium, and product. The method includes: providing, by a server, state information to a client, so that the state information is used to indicate request processing performance of the server, and the state information may represent a request processing speed of the server to some extent; and sending, by the client, a first request to the server when a playback progress of a first content sequence on the client reaches a progress threshold determined based on the state information, so that the server with the request processing performance may feed a second content sequence for playing and display after the first content sequence back to the client in response to the first request.

Abstract: This disclosure provides systems, devices, apparatus, and methods, including computer programs encoded on storage media, for Gaussian splatting ray tracing for photo-realistic simulations. A graphics processor may generate a simulated image frame based on an input image frame and a first set of GS parameters associated with a GS training model and a first ray tracing operation. The graphics processor may determine a second set of GS parameters based on the simulated image frame and a loss function. The graphics processor may generate an optimized simulated image frame based on the simulated image frame, the second set of GS parameters, and a second ray tracing operation. The graphics processor may output the optimized simulated image frame.

Abstract: According to embodiments of the disclosure, a method, an appratus, a device, a medium and a program product for notification message push are provided. The method includes: determining, in response to a trigger for message display, whether a notification message is cached, the cached notification message remaining undisplayed for a target display period; determining, in response to determining that one or more notification message are cached, whether at least one of the one or more cached notification message satisfies a corresponding display rule; and performing push of the at least one notification message in response to determining that the at least one notification message satisfies the corresponding display rule.

Abstract: Embodiments include methods executed by a processor of a robotic device for selecting a frontier goal for autonomous map building within a space, including determining trajectory costs for the robotic device traversing from an occupied area to each of a plurality of available frontier goals, wherein the plurality of available frontier goals include positions within the space from which the robotic device is configured to collect information to autonomously build a map of the space, determining co-visibility costs for each of the plurality of available frontier goals, determining a frontier cost for each of the plurality of available frontier goals based on a difference between the trajectory cost and the co-visibility cost of the respective available frontier goal; and selecting one of the plurality of available frontier goals having a lowest determined frontier cost.

Abstract: One or more processors of a computing device may receive image data obtained via an image sensor of a camera. The one or more processors may apply one or more horizontal filters to the image data to generate horizontally filtered image data and may apply one or more vertical filters to the image data to generate vertically filtered image data. The one or more processors may generate a first accumulation matrix for the horizontally filtered image data and may generate a second accumulation matrix for the vertically filtered image data. The one or more processors may determine autofocus statistics based on the first accumulation matrix and the second accumulation matrix and may output information to adjust one or more lenses of the camera based on the autofocus statistics.

Abstract: Methods and devices for improving power added efficiency in multi-stage power amplifiers. The disclosed techniques implement harmonic termination at the driver amplifier while accounting for parasitic elements. The described teachings improve power added efficiency, enhance reliability through reduced peak voltages, and maintain or improve linearity. The techniques are effective at higher operating frequencies and can be applied to both single-ended and differential amplifier architectures. In one embodiment, a multi-stage power amplifier system includes a driver amplifier (DA) stage coupled through an interstage matching network to a power amplifier stage. A DA harmonic termination circuit provides an approximate short circuit at second harmonic frequencies and an approximate open circuit at third harmonic frequencies.

Abstract: Provided in the present invention are a compound as shown in formula I, various crystal forms thereof, a hydrate, a solvate or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition. The compound of the present invention can effectively treat Alzheimer's disease or Down's syndrome, especially cognitive function impairment caused by Alzheimer's disease or Down's syndrome. Also disclosed in the present invention is use of a ubiquitin specific protease USP25 encoded and expressed by chromosome 21 for preventing, treating or ameliorating Alzheimer's disease or Down's syndrome.

Abstract: The invention discloses a sucking particle for heat-not-bum cigarettes, which comprises the following components by weight fraction: 8-20 parts of microcrystalline cellulose, 50-80 parts of tobacco powder, 0.5-2 parts of tobacco pyrolysate, 1 part of physiological taste adjusting component of tobacco, 8-30 parts of atomizing agent, 0.1-2 parts of tobacco essence and 1-10 parts of propylene glycol; the present invention further provides a manufacturing method for the above product. The product has the benefits of good heating performance, rapid atomizing when heated at 250-310° C. with a heating sheet, complete heating and considerable smoke, similar tobacco aroma and physiological satisfaction as smoking traditional cigarettes and less processing difficulty.

Abstract: A strain-sensing device includes a flexible printed circuit and a strain sensor formed on the flexible printed circuit. The flexible printed circuit includes a stacked set of layers. Each layer in the stacked set of layers has a glass transition temperature (Tg) greater than 50 degrees Celsius (50° C.), and each pair of adjacent layers in the stacked set of layers has a Tg greater than 50° C. The stacked set of layers, as a whole, also has a Tg greater than 50° C.

Abstract: One or more processors of a computing device may receive image data obtained via an image sensor of a camera. The one or more processors may apply one or more horizontal filters to the image data to generate horizontally filtered image data and may apply one or more vertical filters to the image data to generate vertically filtered image data. The one or more processors may generate a first accumulation matrix for the horizontally filtered image data and may generate a second accumulation matrix for the vertically filtered image data. The one or more processors may determine autofocus statistics based on the first accumulation matrix and the second accumulation matrix and may output information to adjust one or more lenses of the camera based on the autofocus statistics.

Abstract: A heating component includes: a heating element; and a pipe body. The heating element includes a heating main body that generates infrared light in a powered-on state. The heating main body is arranged in a hollowed-out cylindrical shape and is spaced apart from the pipe body. The pipe body allows the infrared light to pass through. A transmittance of the pipe body to infrared light at wavelengths of 2-4.75 ?m is more than or equal to 50%.

Abstract: A heating structure includes: a tube body having a cavity and a pipe wall transparent to infrared light; and a heating element at least partially arranged in the cavity, at least partially spaced apart from the pipe wall, and that radiates infrared light to pass through the tube body so as to heat an aerosol-generating substrate. The heating element has a first dimension in a transverse direction. The cavity has a second dimension in the transverse direction. A ratio of the first dimension to the second dimension is greater than or equal to 0.65 and less than 1.

Abstract: An aerosol generating device includes a heating element for generating infrared light; a housing having a housing wall that allows the infrared light to pass through, the heating element and the housing wall being at least partially spaced apart; a first temperature obtaining unit that obtains the housing wall temperature of the housing wall; a second temperature obtaining unit that obtains the heating element temperature of the heating element; and a control unit that: outputs a target control temperature based on a preset temperature and the housing wall temperature, processes the heating element temperature and the target control temperature using a preset algorithm, and adjusts power supplying of the heating element.

Abstract: A heating structure includes: a heating element configured that generates infrared light in a power-on state; and a tube body that allows the infrared light to penetrate through. The heating element is at least partially accommodated in the tube body, and a gap is at least partially formed between the heating element and an inner wall of the tube body. An included angle formed between a central axis of the heating element along a length direction of the heating element and a central axis of the tube body along the length direction of the tube body is less than or equal to 5°.

Abstract: A heating structure includes: a heating element for generating infrared light in a power-on state; a tube body that allows the infrared light to penetrate through; and a thermal resistance temperature measuring element. The heating element is at least partially accommodated in the tube body. The thermal resistance temperature measuring element comprises a first temperature measuring segment and a second temperature measuring segment that are provided on a peripheral surface of the tube body, the first temperature measuring segment and the second temperature measuring segment being connected so as to form a temperature measuring loop. The peripheral surface of the tube body includes a plurality of temperature zones along an axial direction of the tube body. A resistance of the first temperature measuring segment is greater than a resistance of the second temperature measuring segment. The first temperature measuring segment is provided corresponding to one temperature zone.

Abstract: A heating component includes: an infrared light transmitting pipe body; and a heating member for generating infrared light. The infrared light transmitting pipe body includes an opening, and the heating member is disposed in the infrared light transmitting pipe body and at least partially spaced apart from a pipe wall of the infrared light transmitting pipe body. The heating component also includes a temperature sensing member having a temperature sensing probe disposed between the heating member and the opening.

Abstract: A heating structure includes: a heating component; a tube body; and a mounting member. The tube body is provided with a tube opening. The mounting member is assembled with an end of the tube body provided with the tube opening. The heating component includes a heating portion and a conductive portion. The heating portion is arranged in the tube body and is at least partially spaced apart from a tube wall of the tube body so as to radiate infrared light through the tube body to heat an aerosol-generating substrate. The conductive portion penetrates through the mounting member and is connected to the heating portion so as to fix the heating component to the mounting member.

Abstract: A heating control method for a heat-not-burn device that includes a heating element for heating an aerosol-forming substrate includes: controlling the heating element so as to increase from an initial temperature to a first temperature when heating is started, and maintaining the first temperature; controlling the heating element so as to increase from a current temperature to a second temperature when detecting a puffing action, the second temperature being greater than the first temperature; and controlling the heating element so as to decrease from a current temperature to a third temperature when detecting that the puffing action ends, the third temperature being less than the second temperature.

Abstract: A heating control method for a heat-not-burn device that includes a heating element and a temperature measurement module includes: performing heating control on the heating element in a power control mode in a preheat stage so as to preheat an aerosol-forming substrate; and obtaining, in a heating stage subsequent to the preheating stage, a temperature detected by the temperature measurement module, and performing heating control on the heating element in a temperature control mode so as to cause a temperature of the heating element to maintain at a preset heat preserving temperature.