Abstract: Provided is an anti-B7-H4 antibody containing a VH, wherein the VH contains the following CDRs or a mutation thereof: CDR1 as shown in the amino acid sequence of SEQ ID NO: 4 or 5, CDR2 as shown in the amino acid sequence of SEQ ID NO: 15, and CDR3 as shown in the amino acid sequence of SEQ ID NO: 24 or 25, and wherein the mutation is an insertion, deletion or substitution of 3, 2 or 1 amino acid(s) in the amino acid sequences of the CDRs. The antibody has the activity of binding to human B7-H4 and cynomolgus monkey B7-H4. The antibody still retains the activity of binding to human B7-H4 and cynomolgus monkey B7-H4 when prepared into a B7-H4×CD3 bispecific antibody, and has a strong killing effect on tumor cells. The antibody induces a very low expression of nonspecific cytokines such as IL-6 and IFN-?, and exhibits a strong in vivo anti-tumor activity.

Abstract: A splicing display apparatus for floating images and a multi-layer display device comprising the same are disclosed. The splicing display apparatus comprises: a display module configured to emit display light constituting a target image. The display module comprises a plurality of display portions arranged at intervals along a first direction. Each display portion is configured to display a corresponding portion of the target image. The splicing display apparatus further comprises a plurality of optical imaging modules configured to receive the display light emitted from the display modules to form a plurality of floating sub-images in the air. Each optical imaging module has an object plane and an image plane.

Abstract: A splicing display apparatus for floating image and a multi-layer display device comprising the same are disclosed. The splicing display apparatus comprises: a display module configured to emit, on a display plane thereof, display light constituting a target image; a plurality of optical imaging modules configured to receive the display light to form a floating image in the air; and a one-dimensional scattering screen to scatter light in the y-direction, wherein each of the plurality of optical imaging modules comprises: a first one-dimensional conjugate imaging element to converge light beams from points on the display plane onto the one-dimensional scattering screen in the y-direction; and a second one-dimensional conjugate imaging element to converge light beams from points on the display plane onto a floating image plane different from the plane where the one-dimensional scattering screen is located in the x-direction.

Abstract: A method, apparatus and computer program is described comprising: collecting mobile communication fingerprint data for signals between a user device and a plurality of communication nodes of a mobile communication system; organising the collected data into a feature matrix, wherein the feature matrix includes a user device location associated with each set of fingerprint data; generating a binomial expression of the system based on the collected data; processing the binomial expression (e.g. using a factorisation machine) to generate a reduced dimension binomial expression model; and calculating gradients and updating parameters of the reduced dimensional binomial expression model based on said gradients.

Abstract: A splicing display apparatus for floating images and a multi-layer display device comprising the same are disclosed. The splicing display apparatus comprises: a display module configured to emit display light constituting a target image. The display module comprises a plurality of display portions arranged at intervals along a first direction. Each display portion is configured to display a corresponding portion of the target image. The splicing display apparatus further comprises a plurality of optical imaging modules configured to receive the display light emitted from the display modules to form a plurality of floating sub-images in the air. Each optical imaging module has an object plane and an image plane.

Abstract: Embodiments of the present disclosure relate to fingerprint positioning in a wireless communication network. A method for establishing a positioning model comprises: obtaining, at a first device, a set of training data comprising historical measurements and historical regions, a historical measurement being associated with a second device, the second device being within one of the historical regions when the historical measurement is obtained; and training the positioning model by using the historical measurements as input of the positioning model and the historical regions as output of the positioning model to obtain parameter sets of Gaussian distributions of the positioning model, the Gaussian distributions indicating probabilities that a third device is positioned in the historical regions, and the parameter sets corresponding to respective non-light of sight levels of the historical regions. In this way, the positioning accuracy of fingerprint positioning method can be greatly improved.

Abstract: Embodiments of the present disclosure relate to fingerprint positioning in a wireless communication network. A method for establishing a positioning model comprises: obtaining, at a first device, a set of training data comprising historical measurements and historical regions, a historical measurement being associated with a second device, the second device being within one of the historical regions when the historical measurement is obtained; and training the positioning model by using the historical measurements as input of the positioning model and the historical regions as output of the positioning model to obtain parameter sets of Gaussian distributions of the positioning model, the Gaussian distributions indicating probabilities that a third device is positioned in the historical regions, and the parameter sets corresponding to respective non-light of sight levels of the historical regions. In this way, the positioning accuracy of fingerprint positioning method can be greatly improved.

Abstract: The present invention relates to a floating display apparatus and a multi-layer display device comprising the same.

Abstract: Disclosed is a binding protein having at least two protein functional regions, the binding protein comprising a protein functional region A and a protein functional region B; the protein functional region A and the protein functional region B target different antigens or epitopes, the protein functional region A is a Fab or a scFv structure, the protein functional region B is a VH structure, and there are one or more of each of the protein functional region A and the protein functional region B. A multi-specific binding protein has a smaller molecular weight, fewer polypeptide chains, and a simpler structure. By means of different structure types, relative positions, binding valence and other parameters, the functional activities for different targets can be adjusted, and then different combinations of activities can be designed so as to meet the needs of different dose combinations of clinical combinations.

Abstract: Provided in the present disclosure is a mixture, comprising 86-89 wt % of a methionine hydroxy analog and an oligomer thereof, more than 99.95 wt % being a monomer, dimer and trimer, and the ratio of monomer:dimer:trimer by weight being 77-80:18.5-19.5:3-4; 9.2-13.5 wt % of water; and less than 0.5 wt % of ammonium sulfate and ammonium bisulfate. The viscosity of the mixture at 10° C. is lower than 200 mPa·s. Further provided is a method for processing a mixture containing a methionine hydroxy analog and an oligomer thereof.

Abstract: A head-mounted display optical module includes an optical lens group located at a light-emitting display side of the display panel and a protective layer located on an optical path between the display panel and the optical lens group. The protective layer includes at least one first protective layer. A refractive index of the first protective layer continuously changes therein at least along a radial direction that is located in a plane of the first protective layer and points from a center of the first protective layer to an edge of the first protective layer.

Abstract: Disclosed is a testing device for measuring interfacial shear properties between fibers and media, including a main body, which is a rectangular plate-like structure with L-shaped plates provided at the bottom ends of the main body, a connecting rod provided at a top right of the main body, a groove provided at the top of the main body; and four rotating grooves are provided inside the groove. The rotating grooves are cylindrical structures with raised centers at both ends; and a mounting piece is installed above the left end of the main body; a magnet of a displacement micrometer is connected to a tension trolley, a high-definition camera is turned on, weights are added into a loading bucket and the fiber movement is observed until the fiber is pulled out or sliding friction occurs, and then the camera is stopped and accurate data is tested.

Abstract: Disclosed is a testing device for measuring interfacial shear properties between fibers and media, including a main body, which is a rectangular plate-like structure with L-shaped plates provided at the bottom ends of the main body, a connecting rod provided at a top right of the main body, a groove provided at the top of the main body; and four rotating grooves are provided inside the groove. The rotating grooves are cylindrical structures with raised centers at both ends; and a mounting piece is installed above the left end of the main body; a magnet of a displacement micrometer is connected to a tension trolley, a high-definition camera is turned on, weights are added into a loading bucket and the fiber movement is observed until the fiber is pulled out or sliding friction occurs, and then the camera is stopped and accurate data is tested.

Abstract: An augmented reality optical module includes a relay lens group and a reflection lens group. The relay lens group receives and converges the light emitted by the image source. The reflection lens group comprises a first lens and a second lens. The light emitted by the image source is incident to the relay lens group and converged to form the relay image at least once, the light of the last relay image is incident to a first surface of the first lens and reflected, the reflected light is incident to a first surface of the second lens and reflected, and then incident to the first lens and transmitted through the first lens to form imaging light. The ambient light is transmitted in such a manner that the ambient light is transmitted through the second lens and the first lens, sequentially, and then emitted to be superimposed on the imaging light.

Abstract: The invention relates to an optical imaging system (100) and a device for floating display, and a surround-view display device (2000).

Abstract: A method for treating acrolein reactor wastewater, comprising the steps of: S1. mixing acrolein reactor wastewater and a carbonate aqueous solution to obtain a mixed solution, wherein the acrolein reactor wastewater has a pH value of less than 2 and contains 500 ppm to 3,000 ppm of acrolein, 50 ppm to 800 ppm of allyl alcohol, 40,000 ppm to 100,000 ppm of acrylic acid, 10,000 ppm to 30,000 ppm of formaldehyde, 3,000 ppm to 10,000 ppm of acetic acid and 3,000 ppm to 8,000 ppm of maleic acid; and the mixed solution has a pH value of 4 to 6, a COD concentration ranging from 7,500 ppm to 30,000 ppm, and a formaldehyde concentration ranging from 800 ppm to 4,000 ppm; S2. conveying the mixed solution obtained in step S1 to an anaerobic reactor (4) for biochemical treatment; and S3. conveying the solution treated in step S2 to an aerobic biochemical tank (5) for treatment; and reflowing at least one part of the solution treated in step S2 and/or S3 to step S2.

Abstract: Provided are methods of using bromodomain-containing protein 9 inhibitor (I-BRD9) or a derivative thereof in preparation of anti-epileptic drugs. The I-BRD9 has significant effects on anticonvulsion, prolonging of convulsion latency, and reduction of seizure level, and can be used for preparing anti-epileptic drug preparations.

Abstract: A bidirectional variable cross-section water-pressure bearer cycle test system for a coal mine water inrush model test, comprising a water-pressure loading portion and a water-pressure bearer portion, wherein the water-pressure loading portion has a water supply tank, a loading water pump, a water piezometer, a water control valve, a water inlet pipe, a water discharge pipe, etc., through the loaded water pressure to control the cyclic loading of the water pressure. The water-pressure bearer portion has a variable cross-section water-pressure bearer assembly and a airtight main frame variable water-level water-pressure bearer assembly.

Abstract: The present disclosure provides a lighting display device, including: a light source module, a light shield module, and a projection lens module; the light source module includes a light source array unit, a first light shield array unit, and a light receiving lens array unit; the light source array unit includes a plurality of light sources which are independently controlled, the first light shield array unit includes first light shields disposed outside each light source, the light receiving lens array unit includes a plurality of light receiving lenses; the light shield module includes a light-transmitting substrate having a plurality of light-transmitting parts, a light-shielding pattern is disposed on the light-transmitting parts; the projection lens module includes a second light shield array unit, and a projection lens array unit; the second light shield array unit contains multiple second light shields, the projection lens array unit contains multiple projection lenses.

Abstract: A head-mounted display optical module includes an optical lens group located at a light-emitting display side of the display panel and a protective layer located on an optical path between the display panel and the optical lens group. The protective layer includes at least one first protective layer. A refractive index of the first protective layer continuously changes therein at least along a radial direction that is located in a plane of the first protective layer and points from a center of the first protective layer to an edge of the first protective layer.