Patents by Inventor Lei Shi

Lei Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122865
    Abstract: The present disclosure provides methods of protecting ribonucleic acid (RNA) from degradation under certain conditions by contacting the RNA with an amino acid. The present disclosure also provides compositions comprising such amino acid(s) and RNA.
    Type: Application
    Filed: February 15, 2022
    Publication date: April 18, 2024
    Applicant: Pfizer Inc.
    Inventors: Justin Leigh Bellenger, Ye Che, Miguel Angel Garcia, Lei Hu, Mark Carl Noe, Shuai Shi
  • Publication number: 20240122844
    Abstract: The present disclosure relates to a carrier for sustained-release of a drug and use thereof. The carrier is used to carry a drug. The carrier is in a gel state, a semi-solid state, or a solid state. The carrier includes a polyol fatty acid ester as a main component and a hydrogenated vegetable oil dissolved in the polyol fatty acid ester. The state of the sustained-release carrier can be adjusted by adjusting the amount of the dissolved hydrogenated vegetable oil.
    Type: Application
    Filed: August 15, 2023
    Publication date: April 18, 2024
    Inventors: Lei ZHANG, Kewang LU, Yu SUN, Tuojiang WU, Xiaojun SHI, Ling ZHU, Jie WEI, Yang SONG, DAVID LUK
  • Patent number: 11957698
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising a synergistic combination of thermolysin and at least one aminoglycoside antibacterial agent.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: April 16, 2024
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Aleksa Jovanovic, Lei Shi, Eric Roche, Paul Renick
  • Publication number: 20240117122
    Abstract: Provided are a porous silicone resin and a light-weight flexible flame-retardant composite material, belonging to the technical field of nano-porous materials. The porous silicon resin is prepared from a porous silicon resin precursor solution by means of curing and drying processes. The porous silicone resin precursor solution includes a flame retardant, a surfactant, a siloxane monomer, a catalyst, an auxiliary agent and a solvent. The porous silicone resin precursor solution is obtained by firstly dissolving the flame retardant and the surfactant in the solvent, and then adding the siloxane monomer, the catalyst and the auxiliary agent and mixing them uniformly. The porous silicone resin and the light-weight flexible flame-retardant composite material prepared therefrom have the excellent properties of high porosity, high flame retardancy, high elasticity and high strain.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 11, 2024
    Applicant: AEROSPACE RESEARCH INSTITUTE OF MATERIALS & PROCESSING TECHNOLOGY
    Inventors: Jianjun SHI, Wei WANG, Lei KONG, Zhihai FENG, Yunhua YANG, Junning LI, Jinming WANG, Qiong GENG, Lei ZHAO, Wu LU
  • Patent number: 11954842
    Abstract: The invention discloses a powder leakage monitoring device and a powder leakage monitoring method. The powder leakage monitoring device comprises light field camera, 3D PTZ (3-Dimensional Pan/Tilt/Zoom) and computer. Wherein, the light field camera records original light field images of monitored area; the 3D PTZ under the light field camera adjusts the shooting angle of the light field camera when it rotates according to the set direction; and the computer respectively connects to the light field camera and the 3D PTZ, which generates refocused images corresponding to the original light field images, and determines the spatial coordinates of the powder leakage point and the hazard range of the powder leakage in the monitored area according to the refocused images and the shooting angle. Therefore, the range and accuracy of powder leakage monitoring are both increased by using this invention.
    Type: Grant
    Filed: October 31, 2022
    Date of Patent: April 9, 2024
    Assignee: HUANENG NANJING JINLING POWER GENERATION CO., LTD.
    Inventors: Yudong Liu, Lei Wang, Kai Shi, Yong Xia, Xudong Si, Dongfang Li, Xuedong Liang
  • Publication number: 20240110355
    Abstract: The present disclosure discloses a water-replenishing fishway with an adaptively-adjusted floating dock, comprising: a fishway body, wherein the bottom of the fishway body is rotationally connected with a floating dock structure, an auxiliary swimming structure is arranged inside the fishway body, and an adjusting structure used to adjust the auxiliary swimming board of the auxiliary swimming structure is arranged on said floating dock structure. The present disclosure can adaptively adjust the angle of the fishway body and auxiliary swimming board and effectively assist the fish's migration.
    Type: Application
    Filed: February 8, 2022
    Publication date: April 4, 2024
    Inventors: Huichao DAI, Junjun TAN, Dingguo JIANG, Lei CHEN, Xiaotao SHI, Yu WANG
  • Patent number: 11946061
    Abstract: The invention relates to novel methods and compositions for conferring tolerance to glyphosate to plants. The invention also provides glyphosate-tolerant plants, seeds, tissue, cells, and plant parts comprising modified EPSP synthases and recombinant DNA molecules encoding modified EPSP synthases, as well as methods of producing the same and the use thereof.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: April 2, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Guillermo A. Asmar-Rovira, Stephen M. Duff, Shirley X. Guo, Jingdong Liu, R. Douglas Sammons, Lei Shi
  • Publication number: 20240100975
    Abstract: A contactor for a vehicle, includes: a first wiring terminal, a second wiring terminal, a conducting bar, and a driving assembly. A first conduction section and a second conduction section of the conducting bar are connected to each other and are configured to rotate with respect to each other. The first conduction section is fixed on the first wiring terminal, and the second conduction section is electrically connected to or electrically disconnected from the second wiring terminal. The driving assembly is configured to drive the second conduction section to move toward or away from the second wiring terminal. The first wiring terminal and the second wiring terminal are disposed opposite to the conducting bar in a first direction, the driving assembly is disposed opposite to the conducting bar, or the first wiring terminal, or the second wiring terminal in a second direction different from the first direction.
    Type: Application
    Filed: December 1, 2023
    Publication date: March 28, 2024
    Inventors: Tuodi HUANG, Xuechao WANG, Lei SHI, Dengyan YAN, Qing LIU
  • Publication number: 20240102029
    Abstract: The present disclosure relates to a two-plasmid system for prime editing in yeast, use thereof, and a method for gene prime editing in yeast. The two-plasmid system includes a first plasmid and a second plasmid. The first plasmid includes a sequence encoding for an epegRNA. The epegRNA is an RNA molecule including a motif at a 3?-terminus of a pegRNA, and the motif having a sequence as set forth in SEQ ID NO. 12. The second plasmid includes a sequence encoding for a fusion protein of a nucleic acid nickase nCas9 fused with a reverse transcriptase M-MLV RT. The two-plasmid expression system can be used in gene editing in yeast.
    Type: Application
    Filed: April 16, 2023
    Publication date: March 28, 2024
    Inventors: Zehua BAO, Xiaoxiao SHI, Weiyu XIE, Lei DENG, Zhenkun CAI
  • Patent number: 11940721
    Abstract: A projection display device and a projection display equipment are provided. The projection display device includes a display screen body, a photosensitive device, and a control module. The control module is electrically connected to the display screen body, the photosensitive device outputs a photosensitive signal when sensing a projection light beam, and the control module is electrically connected to the photosensitive device to receive the photosensitive signal and to control a section on the display screen body corresponding to a projection position of the projection light beam to be converted from a transparent state to an opaque state according to the photosensitive signal.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: March 26, 2024
    Assignee: Shenzhen China Star Optoelectronics Semiconductor Display Technology Co., Ltd.
    Inventors: Lei Wen, Zhiqing Shi, Miao Jiang, Jiangbo Yao, Lixuan Chen, Xin Zhang
  • Patent number: 11939320
    Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 26, 2024
    Assignee: AbbVie Inc.
    Inventors: Jennifer M. Frost, Lei Shi, Yunsong Tong, Michael J. Dart, Kathleen J. Murauski
  • Patent number: 11938173
    Abstract: Provided are methods for repairing a wound or inducing the proliferative phase of a wound comprising administering a composition comprising a protease mixture comprising collagenases and a neutral protease to the wound in an amount effective for repair of wound tissue or for inducing the proliferative phase in the wound.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: March 26, 2024
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Ira Herman, Vincent Ronfard, Lei Shi
  • Publication number: 20240098123
    Abstract: Systems and methods of the present disclosure include a method for increasing teleconferencing bandwidth efficiency via presentation of remotely accessible content. The method includes receiving a request to present content to a teleconference from a presenting participant device of the teleconference. The method includes generating a unit of software instructions that is configured to cause a participant device to access the content from an originating location that differs from the presenting participant device, and display the content within a shared content interface of the teleconference configured to display a view of the content that is consistent between each participant device of the teleconference. The method includes providing the unit of software instructions to one or more non-presenting participant devices of the teleconference.
    Type: Application
    Filed: September 16, 2022
    Publication date: March 21, 2024
    Inventors: Qianjun Gan, Lei Shi, Yichen Huang, Aobo Zhou
  • Publication number: 20240092679
    Abstract: The present invention discloses a fabrication method and use of a ?40 mm large-size and high-contrast fiber optic image inverter, belonging to the field of manufacturing of fiber optic imaging elements. The light-absorbing glass for preparing the ?40 mm large-size and high-contrast fiber optic image inverter consists of the following components in molar percentage: SiO2 60-69.9, Al2O3 1.0-10.0, B2O3 10.1-15.0, Na2O 1.0-8.0, K2O 3.0-10.0, MgO 0.1-1.0, CaO 0.5-5.0, ZnO 0-0.1, TiO2 0-0.1, ZrO2 0.1-1.0, Fe2O3 3.0-6.5, Co2O3 0.1-0.5, V2O5 0.51-1.5 and MoO3 0.1-1.0. The fiber optic image inverter has the advantages of low crosstalk of stray light, high resolution and high contrast.
    Type: Application
    Filed: July 20, 2023
    Publication date: March 21, 2024
    Inventors: Lei Zhang, Jinsheng Jia, Yue Zhao, Yu Shi, Huichao Xu, Haoyang Yu, Jing Zhang, Zhiheng Fan, Xian Zhang, Xiaofeng Tang, Puguang Song, Jiuwang Wang, Yun Wang, Yang Fu, Yajie Du, Yonggang Huang
  • Publication number: 20240096869
    Abstract: A transient voltage suppression (TVS) device. The TVS device may include a substrate, comprising a polarity of a first type. The TVS device may further include a first dopant layer, disposed on a first surface of the substrate, the first layer comprising a polarity of a second type, wherein the first dopant layer forms a P/N junction with the substrate. The TVS device may include a first buffer layer, disposed on the first dopant layer, and a first outer contact layer, disposed on the first buffer layer.
    Type: Application
    Filed: September 15, 2023
    Publication date: March 21, 2024
    Applicant: Littelfuse Semiconductor (Wuxi) Co., Ltd.
    Inventors: Lei Shi, Jifeng Zhou, Xingchong Gu
  • Publication number: 20240096729
    Abstract: A packaged device includes a circuit board, an electronic component, and a heat storage portion. The electronic component is electrically coupled to the circuit board; and the heat storage portion is disposed on the circuit board or embedded in the circuit board, and the heat storage portion is adjacent to the electronic component, where a specific heat capacity of the heat storage portion is higher than a specific heat capacity of the circuit board, and the heat storage portion is configured to store and release heat. A heat storage material with a relatively high specific heat capacity is introduced into the packaged device, and the heat storage portion is disposed on the circuit board around the electronic component where a large amount of heat generated by the electronic component in a short time can be quickly stored in the heat storage portion and then released to the outside.
    Type: Application
    Filed: September 15, 2023
    Publication date: March 21, 2024
    Inventors: Dong Chen, Fenglong Lu, Yunyu Tang, Lei Shi, Yunfeng Liu, Shuyi Lv, Pengcheng Zhang
  • Publication number: 20240081184
    Abstract: The present invention relates to the field of water surface treatment, and in particular to a cleaning ship for water surface treatment for harvesting water plants. In order to solve the technical problems that the existing cleaning ship cannot adapt to the waters of different depths for harvesting water plants, and a hull has low load utilization rate for the collected water plants and affects the overall working efficiency and the fuel economy of the hull, the present invention provides a cleaning ship for water surface treatment for harvesting water plants, comprising a steel belt conveying mechanism, a driven shaft and the like. The steel belt conveying mechanism drives the driven shaft to rotate.
    Type: Application
    Filed: September 1, 2023
    Publication date: March 14, 2024
    Inventors: Cheng Wu, Fengliang Dong, Xiaoyu Xue, Lei Gao, Peisong Wu, Yunfei Qian, Lijing Yao, Junyi Shi
  • Publication number: 20240083275
    Abstract: A vehicle has an energy conversion apparatus. The energy conversion apparatus includes a first switch module and a second switch module, and configures the second switch module between a power battery and a voltage transformation module. When the first switch module is closed, the power battery, the first switch module, an energy storage module, and an external power supply module form a first charging loop. When the second switch module is closed, the power battery, the second switch module, the voltage transformation module, the energy storage module, and the external power supply module form a second charging loop.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 14, 2024
    Inventors: Xiangxiang LI, Weicheng LI, Lei SHI, Mingwen CHEN
  • Publication number: 20240081271
    Abstract: A dust removal-sterilization-deodorization integrated intelligent lightweight device for livestock and poultry houses includes: a transparent housing, a photocatalyst slidably connected to an inner wall of the transparent housing, filter sleeves rotatably mounted on the inner wall of the transparent housing, a flow guide cavity defined in the transparent housing, a fan fixedly connected to a left sidewall of the flow guide cavity, and a flow baffle fixedly connected to an air inlet end of the flow guide cavity. The filter sleeve includes a low-resistance melt-blown fabric, a rutile manganese-zinc layer is laid on an outer side of the low-resistance melt-blown fabric, a skeleton fabric is attached to an outer wall of the rutile manganese-zinc layer, and an outer wall of the skeleton fabric is rotatably connected to the inner wall of the transparent housing. At least two filter sleeves are transversely arranged, and the filter sleeves are tubular.
    Type: Application
    Filed: November 19, 2023
    Publication date: March 14, 2024
    Inventors: Zhifang Shi, Lei Xi, Xuanyang Li, Pu Cheng, Chunhui Hua, Sixin Zhang, Limin Wang
  • Patent number: D1024104
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: April 23, 2024
    Assignee: BEIJING BYTEDANCE NETWORK TECHNOLOGY CO., LTD.
    Inventors: Yuxing Liu, Yilang Shi, Lei Liu