Abstract: The present invention provides an ultrasound neuromodulation actuator including a stable hollow silica nanoparticle (HSN) structure, in particular, a PEGylated HSN (pHSN) particle, and a method for preparing the same. The present invention also provides methods for enhancing ultrasound stimulation and treating neurological disorders of a subject including applying the pHSN particles to a brain region of the subject followed by ultrasound stimulation.

Abstract: Provided is a back cover. The back cover includes a body, a movable member, and a first to-be-sensed member. The body includes a notch. The movable member is movably disposed on the body. The first to-be-sensed member is disposed on the movable member. When the movable member is located in a first position relative to the body, a projection of the movable member onto the body is located outside the notch. When the movable member moves to a second position relative to the body, the movable member covers at least part of the notch. Further provided is an electronic assembly having the foregoing back cover. The movable member of the back cover is movable relative to the body, to be located outside the notch or cover at least part of the notch. When the back cover is applied on the electronic device, the movable member is configured to stop an image acquisition assembly of the electronic device to prevent the image acquisition assembly from being accidentally thrown out.

Abstract: A preforming method for a high-strength steel variable-diameter tubular part is provided, which belongs to the technical field of metal forming process. The preforming method for a high-strength steel variable-diameter tubular part includes: selecting a tubular blank; and preparing a tubular blank forming mold, where the tubular blank forming mold includes a preforming mold and a final forming mold; sealing and pressurizing the tubular blank; heating the tubular blank by using electrodes; preforming the tubular part at a constant temperature; maintaining a temperature Tl and moving the preformed tubular part to the final forming mold; finally forming the tubular part. Through two steps of operation of preforming and final forming, and maintaining a temperature during moving the tubular blank between the two steps, so that the conversion of intrametallic structure between the two steps is improved, and the performance of the tubular part is improved.

Abstract: The present disclosure relates to a resonance element for a cavity filter, the resonance element made of a metal sheet and comprising a planar portion to be positioned facing a first inner side of a resonance cavity of the cavity filter and an elongate supporting portion extending from the planar portion towards the second inner side of the resonance cavity opposite to the first inner side and connected therewith in a grounding state, wherein the planar portion is configured to be substantially in an E-shape, an F-shape, an L-shape or a T-shape when viewed along a direction perpendicular to a plane of the planar portion. The present disclosure also relates to a one-piece resonance member comprising the above resonance element and a cavity filter comprising the above-said resonance element and/or the above-said one-piece resonance member.

Abstract: The present disclosure provides a multifunctional climbing operation platform and an operation method thereof. The multifunctional climbing operation platform includes a main machine, clamping devices, a bolt retightening device, and an auxiliary sleeve replacement box, wherein the clamping devices each include: a fixed seat; and a pair of claw bars swingably arranged on the fixed seat and each including a rear bar body and a front bar body hinged together, wherein when the pair of claw bars are opened, an inner angle between the rear bar body and the front bar body is greater than 180°, the main machine and the clamping devices can climb along an object to be climbed, the bolt retightening device can replace different sleeves from the auxiliary sleeve replacement box, and can screw a bolt on the object. The present disclosure has the advantages of a large avoidance range and diverse functions.

Abstract: A method for preparing an activated expanded lymphocyte stock solution includes co-culturing, in a serum-free medium, a lymphocyte activator with peripheral blood mononuclear cells obtained via autologous peripheral whole blood centrifugal extraction, and thus completing lymphocyte culture activation. The cultured activated lymphocytes are placed into a serum-free medium. Subculturing is performed to prepare lymphocyte activation culture. A serum-free medium having a volume which is 5 to 10 times of the lymphocyte activation culture is added to the lymphocyte activation culture. Expansion culture is performed, wherein the number of expansion culture generations is 1 to 5. A step of centrifuging, washing, and collecting the activated expanded lymphocytes is performed.

Abstract: Methods, compositions, and systems for distributing nucleic acids into array regions are provided. The methods, compositions, and systems utilize nucleic acid condensing agents to increase efficiency of distribution of the nucleic acids into the array regions. Various methods for facilitating distribution of the nucleic acids to the array regions are provided.

Abstract: The present disclosure relates to a cover for a cavity filter, comprising a cover body made of plastic and an inner metal layer applied on an inner side of the cover that is in contact with a cavity of the cavity filter, wherein a capacitance-influencing structure is provided on the inner side of the cover and comprises a recess formed in the cover body and/or a protrusion integrally formed with a base of the cover body and/or a non-metallized area in the inner metal layer. The present disclosure also relates to a cavity filter comprising the above-said cover.

Abstract: Provided herein are an apelin receptor (APJ) antibody and its fusion protein with Elabela. Also provided herein is a pharmaceutical composition of a fusion protein with APJ antibody and Elabela, and use thereof in treating, preventing, or alleviating one or more symptoms of pulmonary arterial hypertension, pulmonary hypertension or one or more symptoms of heart failure.

Abstract: The disclosure provides compositions and improved methods for the treatment of cancer comprising administering to a patient the fusion protein of SEQ ID NO: 1 at a less frequent dosing schedule (i.e., a single administration every three weeks or multiple administrations on non-consecutive days).

Abstract: A method for identifying a base in nucleic acid, a computer-readable storage medium, a computer program product, and a system. The method for identifying a base in nucleic acid comprises: mapping a coordinate of each bright spot in a bright spot set corresponding to a template onto an image to be inspected, and determining the position of a corresponding coordinate on said image (S11); determining the intensity of a signal at the position of the corresponding coordinate on said image, the intensity being a corrected intensity (S21); and comparing the intensity of the signal at the position of the corresponding coordinate on said image with the size of a first preset value, and determining a base type corresponding to the position on the basis of the comparison result, so as to achieve base calling (S31). The method may quickly and accurately identify a base, and achieve the determination of an order of nucleotides/bases of at least part of a sequence of a template.

Abstract: The present disclosure provides a display mounting support, including a first wall plate assembly and a hanging hook assembly. The hanging hook assembly is configured for mounting on a back of a display. The first wall plate assembly includes a wall plate, a mounting portion and a hanging portion. The wall plate is configured to be set on a wall surface. The wall plate comprises a top end and a bottom end. The mounting portion is connected to the top end. The mounting portion defines a plurality of first mounting holes. A center axis of each first mounting hole is inclined downwardly from a top and far side of the wall surface to a bottom and near side of the wall surface. The hanging portion is connected to the bottom end, to mount the at least one hanging assembly. A load-bearing strength of the display mounting support is increased and more stable.

Abstract: The present disclosure provides a mobile bracket including a bottom base, a first supporting rod, a second supporting rod, a pitch adjustment assembly and a rotation adjustment assembly. The bottom base is connected to a bottom end of the first supporting rod. The second supporting rod is connected to a top end of the first supporting rod. The pitch adjustment assembly is connected to one end of the second supporting rod far from the first supporting rod. The pitch adjustment assembly is capable of rotating relative to the second supporting rod to adjust a pitch angle. The pitch adjustment assembly includes a mounting plate. The rotation adjustment assembly is rotatably connected to the mounting plate. The rotation adjustment assembly is capable of rotating around an axis perpendicular to the mounting plate to adjust a rotation angle. The rotation adjustment assembly is configured to be connected to a display.

Abstract: Aspects of the present disclosure provide mechanisms for fast hyper frame number (HFN) resynchronization of Packet Data Convergence Protocol (PDCP) Protocol Data Units (PDUs). A wireless communication device (e.g., a PDCP entity at a wireless communication device) can calculate a current PDCP count of a current PDCP PDU of a plurality of PDCP PDUs received from a radio link control (RLC) sublayer based on a PDCP sequence number (SN) of the current PDCP PDU and an HFN of a first missing PDCP PDU after a successfully received PDCP PDU. The PDCP count may be calculated using the HFN of the first missing PDCP PDU in response to a gap between the PDCP count of the first missing PDCP PDU and the actual PDCP count of the current PDCP PDU being greater than a PDCP window size.

Abstract: The invention provides compositions, methods and treatment regimens for treating cancer comprising periodic subcutaneous administration of the fusion protein of SEQ ID NO:1 to a cancer patient resulting in enhanced activation of CD8+ T-cells with minimal effects on regulatory T cell (Treg) expansion and providing enhanced anti-tumor efficacy while also mitigating T cell inactivation/exhaustion.

Abstract: A laundry washing machine includes a removable agitator that removably couples to an impeller base through a lateral coupling that allows for relative movement between an agitator coupler of the removable agitator and a base coupler of the impeller base along a lateral coupling axis that intersects the axis of rotation of the impeller base.

Abstract: Systems and methods are provided for identifying targeted datasets that are configured to facilitate an improvement in the accuracy of an acoustic model included in the automatic speech recognition system. Systems obtain a obtain a test dataset comprising (i) audio data having natural speech utterances and (ii) a transcription of the natural speech utterances. Systems generate a text-to-speech dataset comprising audio data having synthesized speech utterances based on the transcription of the natural speech utterances. Systems apply the test dataset and the text-to-speech dataset to the acoustic model to obtain a first acoustic model output and a second acoustic model output, respectively. Systems identify a first set of errors in the first acoustic model output and a second set of errors in the second acoustic model output. Finally, based on comparing the first set of errors and the second set of errors, an acoustic model error ratio is generated.

Abstract: Provided in the embodiments of the present disclosure are a low frequency radiation unit, an antenna, a multi-frequency shared antenna, and a fusion antenna architecture. The low frequency radiation unit is disposed on a side of a metal reflection plate, and includes a Printed Circuit Board (PCB) dielectric plate 10, a medium support frame 70, a coaxial cable 80, and metal radiators provided on a front side and back side of 10. 70 is connected to the metal radiators, and is configured to support the metal radiators. 80 is disposed on 70, is connected to the metal radiators, and feeds the metal radiators. Such that a 4G low frequency antenna is flexibly disposed above a 5G high frequency antenna, thereby avoiding interference of Balun with the 5G high frequency antenna; and low mutual coupling is achieved, such that internal space of an antenna is saved.

Abstract: The present disclosure discloses a measurement and diagnostic system for weight-bearing lines of lower limbs. The measurement and diagnostic system includes a data loading module, a keypoint selection module, an angle calculation module and a mechanical axis diagnosis and output module, wherein the angle calculation module is configured to calculate slopes among keypoints by using obtained keypoints, characteristic axes and joint lines, and calculate mechanical lateral distal femoral angles, joint line convergence angles, medial proximal tibial angles and lateral distal tibial angles by inverse trigonometric functions; and the mechanical axis diagnosis and output module is configured to compare the obtained angle values with preset values to judge whether a lower limb deformity occurs. The present disclosure further discloses an intelligent measurement method for weight-bearing lines of both lower limbs. The precise coordinates of the keypoints are not required in the present disclosure.

Abstract: Embodiments of the present disclosure provide a music generation method and apparatus, an electronic device and a storage medium. Initial audio is acquired; a first arrangement template corresponding to the initial audio is acquired, where the first arrangement template is used for adding a soundtrack with a target music style to the initial audio; the initial audio is processed based on the first arrangement template to generate target music. After acquiring the initial audio input by the user, the first arrangement template matched with the initial audio is selected, and the initial audio is processed by using the first arrangement template to add the soundtrack with the target music style to the initial audio, thereby generating the target music.