Patents by Inventor Lei Xiao

Lei Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11989956
    Abstract: Systems and methods for object detection generate a feature pyramid corresponding to image data, and rescaling the feature pyramid to a scale corresponding to a median level of the feature pyramid, wherein the rescaled feature pyramid is a four-dimensional (4D) tensor. The 4D tensor is reshaped into a three-dimensional (3D) tensor having individual perspectives including scale features, spatial features, and task features corresponding to different dimensions of the 3D tensor. The 3D tensor is used with a plurality of attention layers to update a plurality of feature maps associated with the image data. Object detection is performed on the image data using the updated plurality of feature maps.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: May 21, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Xiyang Dai, Yinpeng Chen, Bin Xiao, Dongdong Chen, Mengchen Liu, Lu Yuan, Lei Zhang
  • Publication number: 20240158819
    Abstract: Provided is a method for biosynthesis of (R)-?-hydroxytetradecanoate compounds. The method comprises the following steps of: reacting ?-carbonyl tetradecanoate in a ketoreductase and a glucose dehydrogenase or a fusion enzyme thereof, glucose, NADP+ and a buffer solution to obtain (R)-?-hydroxytetradecanoate compounds. The method is an enzyme-catalyzed biosynthesis method having simple operations, conventional equipment and an environmentally friendly process, and the prepared product has high purity, high yield and a high ee value.
    Type: Application
    Filed: January 6, 2021
    Publication date: May 16, 2024
    Inventors: Tianshuai XU, Dayong GONG, Yumel XIAO, Zhanghong WANG, Zhichuan HUANG, Shan HUANG, Lei ZHANG, Xin GAO, Junwei SHEN
  • Patent number: 11981920
    Abstract: Embodiments relate to a modified T cell comprising an antigen binding molecule, wherein expression and/or function of CDC42 in the modified cell has been enhanced. In embodiments, the modified cell has an increased level of cytokine release in response to an antigen that the antigen binding molecule binds as compared to a corresponding T cell that does not overexpress CDC42. In embodiments, the cytokine release comprises a cytokine release of IFN?. In embodiments, the modified cell has an enhanced migration capability in response to a chemokine as compared to a corresponding T cell that does not overexpress CDC42.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: May 14, 2024
    Assignee: Innovative Cellular Therapeutics Holdings, Ltd.
    Inventors: Chengfei Pu, Zhiyuan Cao, Lei Xiao, He Sun
  • Patent number: 11976064
    Abstract: The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: May 7, 2024
    Assignee: Pfizer Inc.
    Inventors: Omar Ahmad, Andrew Fensome, Erik Alphie LaChapelle, Ethan Lawrence Fisher, Rayomand J. Unwalla, Jun Xiao, Lei Zhang
  • Patent number: 11979690
    Abstract: The present application relates to the field of projection technology and discloses a phosphor wheel, a light source module, and a projector. A phosphor wheel includes a base, a first phosphor layer, and a second phosphor layer. The base includes an excitation light reflecting section and an excitation light transmitting section. The first phosphor layer is disposed on a surface of the excitation light reflecting section facing a direction of incident light and spreading along a circumferential direction of the base. The second phosphor layer is disposed on a surface of the excitation light transmitting section facing away from the direction of incident light and spreading along a circumferential direction of the base. The first phosphor layer and the second phosphor layer are offset to each other in a radial direction of the base.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: May 7, 2024
    Assignee: CHENGDU XGIMI TECHNOLOGY CO., LTD
    Inventors: Bo Zhong, Shi Xiao, Lei Yin
  • Publication number: 20240146411
    Abstract: A method for detecting failure of passive wavelength division equipment includes: determining whether base station equipment is pre-modeled; when the base station equipment is not pre-modeled, dividing the first side equipment and the second side equipment in the base station equipment into a plurality of equipment groups; obtaining optical port alarm information of the first side equipment in the base station equipment and/or optical port alarm information of the second side equipment in the base station equipment, or obtaining link disconnection alarm information of the second side equipment in the base station equipment; when no link disconnection alarm information of the second side equipment is obtained, and it is determined, according to the optical port alarm information, that there is an equipment group satisfying a first preset condition, determining that the passive wavelength division equipment corresponding to the equipment group satisfying the first preset condition fails.
    Type: Application
    Filed: May 31, 2022
    Publication date: May 2, 2024
    Inventors: Lei XIAO, Tao YANG
  • Patent number: 11970548
    Abstract: The compositions and methods described herein are directed to treating solid tumors using CAR T therapy and/or antibodies targeting GCC. The compositions include CAR comprising an extracellular domain that binds GCC.
    Type: Grant
    Filed: August 23, 2022
    Date of Patent: April 30, 2024
    Assignees: Innovative Cellular Therapeutics Holdings, Ltd., Innovative Cellular Therapeutics, Inc.
    Inventors: Zhiyuan Cao, Yuzhe Peng, Lei Xiao, Zhao Wu, Le Tian
  • Patent number: 11972252
    Abstract: A docker image is received. The docker image is for a container. The container contains files that allow for virtualization of applications that run within the container. The docker image is parsed to identify layer files in the docker image. Installed software components (e.g., installed files) and/or hardware components in the layer files are identified. Software application index calls are made to generate information that identifies relationships between the installed software components and/or hardware components. The relationships between the installed software components and/or hardware components are then displayed to a user.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: April 30, 2024
    Assignee: Micro Focus LLC
    Inventors: Qiuxia Song, Yi-Ming Chen, Zhong-Yi Yang, Yangyang Zhao, Lei Xiao
  • Publication number: 20240122370
    Abstract: A child crib includes a frame body, a corner component, a cloth component and a covering member. The cloth component at least partially covers the frame body. The corner component is connected to a handrail and a post of the frame body and exposed out of the cloth component. A first ring-shaped opening structure and a second ring-shaped opening structure are respectively formed by a first side and a second side of a covering body of the covering member. When the first side of the covering body is connected to a first side of the cloth component, by positioning the second side of the covering body on a second side of the cloth component, the first side and the second side of the cloth component are respectively enclosed by the first ring-shaped opening structure and the second ring-shaped opening structure, and the covering member covers the corner component.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 18, 2024
    Inventors: Lei XIAO, Bo WU
  • Patent number: 11944645
    Abstract: The present disclosure describes compositions and methods for treating cancer. Embodiments relate to a cell modified to express one or more molecules at a level that is higher or lower than the level of the one or more molecules expressed by a cell that has not been modified to express the one or more molecules, wherein the one or more molecules comprise Cavin3, ZBED2, and MYC.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: April 2, 2024
    Assignees: Innovative Cellular Therapeutics Holdings, Ltd., Innovative Cellular Therapeutics, Inc.
    Inventors: Zhiyuan Cao, Lei Xiao, Yuzhe Peng, Wei Ding, Wensheng Wang
  • Publication number: 20240104921
    Abstract: A method for recognizing product detection missed is performed by an electronic device. The method includes: obtaining a surveillance video collected by a surveillance device on a product production line; generating product detection results by inputting video frames of the surveillance video into a product detection model; generating detecting action recognition results by inputting the video frames of the surveillance video into an action recognition model; and determining whether product detection is missed based on the product detection results and the detecting action recognition results.
    Type: Application
    Filed: May 23, 2022
    Publication date: March 28, 2024
    Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Suhui Yang, Lei Nie, Huihui Xiao
  • Publication number: 20240107467
    Abstract: Methods, systems, and devices for wireless communications are described. A network entity may transmit a set of spatially multiplexed synchronization signals in a same symbol period. The set of spatially multiplexed synchronization signals may indicate a parameter, such as a cell identifier, for the network entity. The network entity may select a sequence for each synchronization signal of the set. A user equipment (UE) may monitor for the set of spatially multiplexed synchronization signals during the same symbol period. The UE may differentiate each synchronization signal based on a respective sequence used to transmit each synchronization signal. The UE may determine that the set of spatially multiplexed synchronization signals were transmitted by the network entity using multiple antenna ports. The UE may determine the parameter for the network entity based on receiving the set of spatially multiplexed synchronization signals.
    Type: Application
    Filed: September 22, 2022
    Publication date: March 28, 2024
    Inventors: Yi Huang, Hung Dinh Ly, Peter Gaal, Jing Jiang, Yu Zhang, Lei Xiao, Yongle Wu
  • Publication number: 20240095531
    Abstract: A method trains a neural network model in a computer system. The neural network model includes one or more layers each including one or more neurons. The one or more layers include at least one first layer and one last layer. Each neurons are configured to perform forward propagation of one or more input values by applying weights to the one or more input values and generating an output value based on a function applied to the sum of the weighted input values. The neurons of any given layer, but the last layer, of the one or more layers are connected with the one or more neurons of a consecutive layer. The neurons of any given layer, but the first layer, of the one or more layers are connected with the one or more neurons of a preceding layer.
    Type: Application
    Filed: November 28, 2023
    Publication date: March 21, 2024
    Inventors: Lei Jiang, Shihai Xiao
  • Patent number: 11932700
    Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: March 19, 2024
    Assignee: Innovative Cellular Therapeutics Holdings, Ltd.
    Inventors: Lei Xiao, Chengfei Pu, Zhiyuan Cao, He Sun, Mao Bi, Zhao Wu
  • Patent number: 11936259
    Abstract: A food processor and an electric motor for a food processor. The electric motor includes: a stator core having a ring-shaped stator yoke and a plurality of stator teeth provided at an inner peripheral face of the stator yoke, two adjacent stator teeth defining a stator slot there between, the plurality of the stator teeth defining a stator hole coaxial with the stator yoke, and an outer contour of a radial section of the stator yoke being substantially circular and having a maximum radial dimension D; and a rotor core rotatably provided in the stator hole and coaxial with the stator hole, the rotor core having a maximum radial dimension d, in which 0.4?d/D?0.55.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: March 19, 2024
    Assignee: GUANGDONG MIDEA CONSUMER ELECTRIC MANUFACTURING CO., LTD.
    Inventors: Xiantang Liang, Liancheng Chen, Congshan Pang, Zhifeng Wang, Lei Xiao, Zhenfeng Yang
  • Patent number: 11937025
    Abstract: The present application relates to the field of projection technology and discloses a phosphor wheel, a light source module, and a projector. A phosphor wheel includes a base, a first phosphor layer, and a second phosphor layer. The base includes an excitation light reflecting section and an excitation light transmitting section. The first phosphor layer is disposed on a surface of the excitation light reflecting section facing a direction of incident light and spreading along a circumferential direction of the base. The second phosphor layer is disposed on a surface of the excitation light transmitting section facing away from the direction of incident light and spreading along a circumferential direction of the base. The first phosphor layer and the second phosphor layer are offset to each other in a radial direction of the base.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: March 19, 2024
    Assignee: CHENGDU XGIMI TECHNOLOGY CO., LTD
    Inventors: Bo Zhong, Shi Xiao, Lei Yin
  • Publication number: 20240085866
    Abstract: The present disclosure provides a method and device for intelligent control of heating furnace combustion based on a big data cloud platform, which relates to the technical field of artificial intelligence control. The method includes: construction of big data cloud platform based on production and operation parameters of the heating furnace; identification of key factors in the production process of the heating furnace by using big data mining technology; independent deployment of traditional heating furnace combustion control systems based on the mechanism model; and integration of cloud platform big data expert knowledge base and the heating furnace combustion intelligent control system.
    Type: Application
    Filed: September 7, 2023
    Publication date: March 14, 2024
    Applicant: University of Science and Technology Beijing
    Inventors: Qing LI, Fengqin LIN, Hui LI, Li WANG, Chengyong XIAO, Xu YANG, Jiarui CUI, Chunqiu WAN, Qun YAN, Yan LIU, Lei MIAO, Jin GUO, Boyu ZHANG, Chen HUANG, Yaming XI, Yuxuan LIN
  • Publication number: 20240080692
    Abstract: Methods, systems, and devices for wireless communications are described. In some wireless communications systems, a user equipment (UE) and a network entity may utilize multi-port mobility reference signals to assist with spatial based mobility procedures. The UE may receive a reference signal that is associated with multiple antenna ports. The UE may measure a multi-dimensional channel response based on the reference signal. The multi-dimensional channel response may be associated with measured channel metrics corresponding to the multiple antenna ports. The UE may transmit a report that includes a channel measurement vector based on the multi-dimensional channel response. The channel measurement vector may indicate multiple measured channel metrics for one or more dimensions of the multi-dimensional channel response. The network entity may transmit a message that indicates one or more metrics associated with mobility management for the UE based on the report that indicates the channel measurement vector.
    Type: Application
    Filed: September 6, 2022
    Publication date: March 7, 2024
    Inventors: Jing Jiang, Jae Won Yoo, Yongle Wu, Lei Xiao, Hari Sankar, Alexei Yurievitch Gorokhov, Yu Zhang, Wei Yang, Jing Lei
  • Publication number: 20240075061
    Abstract: The present disclosure relates to compositions and methods for enhancing infiltration of lymphocytes into tumor tissue, enhancing anti-tumor lymphocyte activities in tumor microenvionment (TME), inhibiting regulatory lymphocyte (e.g., B and T cells) activities in TME, and/or long term benefit of cell therapies. For example, in a method of in vivo cell expansion, the method comprises administering an effective amount of cells comprising an antigen binding molecule to a subject; and administering an effective amount of presenting cells expressing a solid tumor antigen that the binding molecule binds.
    Type: Application
    Filed: December 13, 2022
    Publication date: March 7, 2024
    Applicants: Innovative Cellular Therapeutics Holdings, Ltd., Innovative Cellular Therapeutics, Inc.
    Inventors: Wensheng Wang, Dongqi Chen, Chengfei Pu, Zhao Wu, Lei Xiao, Zhiyuan Cao, Le Tian
  • Publication number: 20240078638
    Abstract: Provided are an image fusion method and apparatus, an electronic device, and a storage medium. The method includes the following steps: A shooting operation acting on a first page of a target shooting activity is received, where the first page is an H5 page; in response to the shooting operation, a camera is called through system shooting software to collect an original image; a fusion operation for the original image is received; and in response to the fusion operation, the original image is fused with a first target effect, a static target image that includes a static image obtained by fusing the original image with the first target effect and the first description information related to the static image is generated, and the static target image is displayed on a second page, where the second page is an H5 page.
    Type: Application
    Filed: November 9, 2023
    Publication date: March 7, 2024
    Inventors: Honghui LIAO, Guangying SU, Weipeng WANG, Tong WU, Feng CHEN, Lei HUANG, Bei WANG, Yiqi XIAO, Yalong LIU