Abstract: Disclosed are molecules useful in the treatment or prevention of viral infections in humans and animals and/or the treatment or prevention of the associated symptoms, diseases and/or conditions. The disclosure provides molecules which comprise sugar (carbohydrate/polysaccharide/sialic acid/glycan)-binding protein(s) which are useful in the treatment or prevention of Coronavirus infections and/or diseases, symptoms and/or conditions caused or contributed to by the same.

Abstract: The present disclosure relates to a support structure provided on one side of a flexible display panel, comprising a bendable region, a non-bendable region and a transitional region between the bendable region and the non-bendable region; the bendable region is provided with a first hollowed-out pattern, and the first hollowed-out pattern comprises a plurality of first hollowed-out holes; the transitional region is provided with a second hollowed-out pattern, and the second hollowed-out pattern comprises a plurality of second hollowed-out holes; the density of the plurality of first hollowed-out holes is greater than the density of the plurality of second hollowed-out holes. The present disclosure also relates to a flexible display apparatus.

Abstract: A method of preparing an air gap includes: forming a first covering layer etching and removing part higher than a horizontal line where a top of the oxide layer is located; forming a first oxide layer on an etched plane; etching the first oxide layer; removing a part of the first oxide layer; reserving a rest part of the first oxide layer; taking a reserved first oxide layer as an oxide layer pattern; forming a second covering layer at a position of a removed part of the first oxide layer; removing the oxide layer pattern and the oxide layer.

Abstract: An organic compound represently by Chemical formula 1 and Chemical formula 2, an electronic component, and an electronic device. The two * in Chemical formula 2 are attached to any two adjacent * of the four * in Chemical formula 1 to form a fused ring. The organic compound can improve the electron transport performance of the electronic component.

Abstract: A supporting back film includes a first supporting structure and a second supporting structure arranged on at least one side of the first supporting structure in a second direction. The second direction intersects with the first direction. An orthographic projection of the first supporting structure on the flexible display panel covers the bendable region, and the first supporting structure is bendable. The volume of the second supporting structure is greater than or equal to the volume of the first supporting structure, and the density of the second supporting structure is less than the density of the first supporting structure. Alternatively, the volume of the first supporting structure is greater than or equal to the volume of the second supporting structure, and the density of the first supporting structure is less than the density of the second supporting structure.

Abstract: A dot projector may include a vertical-cavity surface-emitting laser (VCSEL). The dot projector may include one or more collimating elements to collimate light emitted by the VCSEL. An effective focal length of the one or more collimating elements may be larger than an optics length of the dot projector. The dot projector may include an optical element including a periodic optical phase function to replicate the light after collimation by the one or more collimating elements and an aberration-correcting phase function to correct spot aberrations in a dot pattern resulting from the tiling or splitting of the light.

Abstract: A chimeric antigen receptor (CAR) comprising a polypeptide comprising an extracellular antigen binding domain comprising a first BCMA binding moiety and a second BCMA binding moiety, wherein the first BCMA binding moiety is a first anti-BCMA single domain antibody, and the second BCMA binding moiety is a second anti-BCMA sdAb; and wherein each of the first and second sdAb is a VHH domain.

Abstract: Disclosed are molecules with affinity for (or an ability to bind to) sialic acid (and in particular sialoglycoconjugates) on cell surfaces (these including sialic acid containing glycoproteins and cell surface sialic acid receptors), for use in treating or preventing of inflammatory diseases and/or conditions with an inflammatory aeitiology. The disclosed molecules may be of particular use in the treatment and/or prevention of diseases and/or conditions characterised by inflammation occurring as a consequence of a cascade of cytokines, inflammation that may occur in and around the tissues and/or structures of the lung and inflammation occurring as a result of an infection.

Abstract: The embodiments of the present application belong to the technical field of semiconductor manufacturing, and relate to a semiconductor structure manufacturing method and a semiconductor structure. The semiconductor structure manufacturing method includes: the substrate is provided with a plurality of active area structures and a plurality of first hole structures arranged at intervals, first bonding pad structures are formed in the first hole structures, and the first bonding pad structures are electrically connected to the active area structures; and second bonding pad structures are formed on the first bonding pad structures, and the second bonding pad structures are connected to the first bonding pad structures, and connected to a capacitor structure.

Abstract: Disclosed is a transient-state THz spectrometer applied to cells and biological macromolecules, including a femtosecond laser amplifier. A femtosecond laser output by the femtosecond laser amplifier is divided into two beams of pump light and probe light after passing through a beam splitter of which a transmission-reflection ratio is 7:3, the pump light is focused to irradiate a gap between electrodes of a nonlinear photoconductive antenna and emit a terahertz wave after successively passing through a half wave plate, a silver-plated reflector and a first lens, the terahertz wave forms a terahertz wave collineation after successively passing through a second lens, a slab waveguide, a third lens and an ITO film, the terahertz wave collineation and the probe light form a probe light collineation of wavefront tilt which is perpendicularly incident on a ZnTe crystal and detected and recorded by using a CCD camera.

Abstract: The present disclosure provides a nitrogen-containing compound, an organic electroluminescent device and an electronic apparatus, belonging to the technical field of organic materials. The nitrogen-containing compound of the present disclosure has a carbazole structure and a fluorenyl group, two cooperating with each other and has a high first triplet energy level. Therefore, the nitrogen-containing compound of the present disclosure is suitable for use as a host material of a light-emitting in an organic electroluminescent device. The nitrogen-containing compound can improve the performance of the organic electroluminescent device.

Abstract: Disclosed herein is a novel chimeric antigen receptor and use thereof. The novel chimeric antigen receptor consists of a signal peptide, an antigen binding domain, a transmembrane region, and an intracellular signal domain, and comprises a 4-1BB signal peptide and/or a 4-1BB molecular transmembrane region. Nucleic acid sequences of various chimeric antigen receptors are separated and purified and provided is a chimeric antigen receptor and a CAR-T cell which are specific for a CD19 malignant tumor antigen. In the malignant tumor killing test of hematological cell lines, the ability of immune cells to target and recognize tumor cells is significantly enhanced, and the killing activity against tumor cells is also enhanced.

Abstract: The present invention belongs to the field of gas solubility measurement, and provides a measuring device and method for gas solubility in a natural gas hydrate solution system. The measuring device mainly comprises a reaction system, a sampling system and a data analysis system. The present invention can be used for measuring gas solubility in a natural gas hydrate solution system at different temperature, pressure and salt ion conditions, and exploring influence of different environmental conditions on the gas solubility when hydrate-liquid water biphase equilibrium is achieved. The present invention in characterized in that the structure is simple, the operation is easy, sampling is carried out at a constant pressure to avoid damage to phase equilibrium and dissolution equilibrium of the systems, and a microfilter is used to ensure that a liquid sample taken does not contain hydrate crystals, so that experimental data has a relatively high accuracy.

Abstract: Provided is a method for blockchain-based recordkeeping and implementable by a terminal device. The method comprises: obtaining target data; computing a data digest of the target data, and extracting a key segment from the target data; signing, in a secure operation environment included in the terminal device, the data digest and/or the key segment based on a private key associated with the terminal device to generate a signature; and submitting to a blockchain the data digest, the key segment, and the signature, for one or more nodes in the blockchain to verify the signature based on a public key corresponding to the private key, and to record the data digest and the key segment in the blockchain in response to the signature being verified to be valid.

Abstract: The invention disclose a method, an apparatus, a device and a storage medium for detecting a card surface picture. The method comprises the following steps of: identifying region information of an image to be shown in a target picture; generating a picture to be detected according to the region information of the image to be shown; synthesizing the picture to be detected and a preset picture to obtain a synthesized picture; and in response to that it is detected that a fourth pixel value is contained in the synthesized picture, determining that the target picture is unqualified, which improves the efficiency of picture review and further improves the efficiency of card fabrication.

Abstract: Provided herein are single-domain antibodies targeting BCMA, and chimeric antigen receptors (such as monovalent CAR, and multivalent CAR including bi-epitope CAR) having one or more anti-BCMA single-domain antibodies. Further provided are engineered immune effector cells (such as T cells) having the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

Abstract: The present application relates to the technical field of organic materials, and provides a nitrogen-containing compound, an electronic element and an electronic apparatus. The structure of the nitrogen-containing compound is shown as Chemical formula 1. The nitrogen-containing compound can improve the performance of the electronic element. Ar is II, and X is selected from O or S; L1 is III, and in L1, “#” represents a connection point between the phenylene of L1 and N, and “##” represents a connection point between the phenylene of L1 and IV; L2 is V, and in L2, “#” represents a connection point between the phenylene of L2 and N, and “##” represents a connection point between the phenylene of L2 and R4.

Abstract: A method for intelligently measuring vehicle speed based on a binocular stereo vision system includes: training a Single Shot Multibox Detector neural network to obtain a license plate recognition model; calibrating the binocular stereo vision system to acquire parameters of two cameras; detecting the license plates in the captured video frames with the license plate recognition model, locating the license plate position; performing feature point extraction and stereo matching by a feature-based matching algorithm; screening and eliminating the matching point pairs, and reserving the coordinates of the matching point pair closest to the license plate center; performing stereo measurement on the screened matching point pair to get the spatial coordinates of the position; calculating and obtaining the speed of the target vehicle.

Abstract: A vision-LiDAR fusion method and system based on deep canonical correlation analysis are provided. The method comprises: collecting RGB images and point cloud data of a road surface synchronously; extracting features of the RGB images to obtain RGB features; performing coordinate system conversion and rasterization on the point cloud data in turn, and then extracting features to obtain point cloud features; inputting point cloud features and RGB features into a pre-established and well-trained fusion model at the same time, to output feature-enhanced fused point cloud features, wherein the fusion model fuses RGB features to point cloud features by using correlation analysis and in combination with a deep neural network; and inputting the fused point cloud features into a pre-established object detection network to achieve object detection. A similarity calculation matrix is utilized to fuse two different modal features.

Abstract: A spacecraft nutation inhibition method for low-orbit geomagnetic energy storage in-orbit delivery includes: S1, enabling a delivery connection rod to be slidably connected to two mass blocks in a length direction, and adjusting the center of mass of a spacecraft system to pass through a main connecting shaft; S2, respectively measuring, calibrating and adjusting the center of mass and the principal axis of inertia of the delivery connection rod that is to deliver the space target or de-orbit debris; S3, carrying out energy storage delivery; S4, respectively adjusting the center of mass and the moment of inertia of the delivery connection rod after delivering the space target or de-orbit debris; S5, carrying out energy dissipation and unloading; and S6, enabling the spacecraft system to prepare to grab the next space target or de-orbit debris and proceeding to the next delivery work cycle.