Patents by Inventor Lei Yu

Lei Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250250544
    Abstract: A method for preparing hematopoietic endothelial cells and a method for preparing hematopoietic stem cells are provided, comprising inducing hematopoietic mesodermal cells to express transcription factors LCOR, HOXA9, HOXA5, RUNX1, and ERG at specific time periods during the conversion of induced pluripotent stem cells into the hematopoietic endothelial cells or the hematopoietic stem cells. The method can increase the preparation efficiency of at least one of the hematopoietic endothelial cells and the hematopoietic stem cells (including long-term hematopoietic stem cells).
    Type: Application
    Filed: March 19, 2025
    Publication date: August 7, 2025
    Applicant: ALLIFE MEDICINE (BEIJING) LIMITED
    Inventors: Rulong DU, Lei YU, Wenjing HUANG, Xuening WU, Yuchun GU, Lida WU
  • Patent number: 12348642
    Abstract: An example operation may include one or more of receiving, via a first blockchain peer, a request to verify an identity of a user, performing, via the first blockchain peer, an identity validation of the user via a know your customer (KYC) service provider of a blockchain network, determining whether a digital identity of the user has been previously stored by another blockchain peer on a blockchain of the blockchain network, in response to a determination that the digital identity of the user has not been stored on the blockchain, creating a non-fungible token (NFT) that identifies the user, and appending information about the identity validation of the user to a structure of the NFT and storing the NFT in a block of the blockchain.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: July 1, 2025
    Assignee: International Business Machines Corporation
    Inventors: Nitin Gaur, Sean Dunne, Petr Novotny, Qi Zhang, Lei Yu
  • Patent number: 12319958
    Abstract: Methods of treating disease include measuring a CCR2 profile of a patent, selecting a CCR2 antagonist based on the CCR2 profile of the patient, and administering the CCR2 antagonist to the patient. Methods for stratifying one or more patients for pain medication based on a CCR2 profile include measuring a CCR2 profile of one or more patients and partitioning the one or more patients into predetermined groups or subgroups based on the CCR2 profile of the one or more patients. Kits for performing the methods are also described.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: June 3, 2025
    Assignees: Rutgers, The State University of New Jersey, Plumeria Therapeutics, Inc.
    Inventors: Lei Yu, Thomas P. Richardson
  • Publication number: 20250171371
    Abstract: A method of preparing a high-performance green building material based on combustion flue gas carbon dioxide mineralization, including: calculating a raw material ratio; taking each industrial solid waste material to obtain a solid powder; pouring the solid powder, dihydrate gypsum and gel material into a granulator, mixing uniformly, and then taking a part of the mixture, and then stirring the remaining mixture with deionized water sprayed until spherical kernels are formed, uniformly adding the previously-taken part of mixture to prepare an aggregate; performing hydration reaction on the aggregate; drying the hydrated aggregate to prepare spherical ceramic granules; placing the ceramic granules into a reaction kettle and introducing a combustion flue gas containing CO2 for mineralization reaction, and taking out reacted ceramic granules and putting into drying oven for drying to prepare a cold-bonded lightweight aggregate; supplementing water to the lightweight aggregate to perform hydration reaction and ob
    Type: Application
    Filed: November 30, 2023
    Publication date: May 29, 2025
    Applicant: SOUTHEAST UNIVERSITY
    Inventors: Min SONG, Yue HU, Jiahao LAI, Lei YU
  • Publication number: 20250155939
    Abstract: A foldable apparatus and an electronic device are provided. The foldable apparatus includes a fastened piece and a rotating assembly. The rotating assembly includes a first rotating arm and a second rotating arm that are arranged on two sides of the fastened piece in a width direction of the foldable apparatus, and the first rotating arm and the second rotating arm can rotate relative to the fastened piece, to enable the foldable apparatus to be in a folded state or an unfolded state. The foldable apparatus further includes a stopper, and the stopper is fastened to the fastened piece or connected to the fastened piece in a position-limiting manner.
    Type: Application
    Filed: January 16, 2025
    Publication date: May 15, 2025
    Inventors: Hewen Shen, Ding Zhong, Lei Yu, Li Liao, Yuanhan Yuan, Yadong Qiao
  • Patent number: 12291668
    Abstract: Disclosed is a coated rubber particle, preparation thereof and its application as a plugging material in drilling fluids. The coated rubber particle comprises a rubber core and a coating layer, wherein the core has a fluorine content (at %) of 0-15%, the coating layer has a fluorine content (at %) of 30-80%, and the coated rubber particle has a 24-hour oil absorption rate of 4% or less. The coated rubber particle has good oil resistance, and is particularly suitable for use as a plugging material in drilling fluids, particularly oil-based drilling fluids.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: May 6, 2025
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC OILFIELD SERVICE CORPORATION, SINOPEC SHENGLI PETROLEUM ENGINEERING CO., LTD, DRILLING TECHNOLOGY RESEARCH INSTITUTE OF SINOPEC SHENGLI PETROLEUM ENGINEERING CO., LTD
    Inventors: Gongrang Li, Wenbo Li, Bingxiang Sun, Hui Tian, Xizhou Wang, Ke Li, Jianghong Jia, Lei Yu, Jie Sun, Xudong Wang, Chengjun Wang, Bingtai Li, Haibin Li, Zhendong Liu, Kai Gao, Chunguang Li, Hui Li
  • Publication number: 20250126730
    Abstract: A hinge mechanism and a foldable electronic device are provided. The hinge mechanism is disposed in a foldable electronic device. When one rotation portion of the foldable electronic device moves, the hinge mechanism drives the other rotation portion to move. The hinge mechanism includes a fastening support, a transmission assembly, two first transmission shafts, a clamping assembly, and a first elastic portion. The fastening support is configured to be fastened to a base of the foldable electronic device, and the fastening support is coupled to the first transmission shaft to limit relative positions of the first transmission shaft and the fastening support. The first transmission shaft is coupled to the clamping assembly and the first elastic portion. The first elastic portion provides an elastic force for the clamping assembly such that friction between the clamping assembly and the transmission assembly generates damping.
    Type: Application
    Filed: December 23, 2024
    Publication date: April 17, 2025
    Inventors: Hewen Shen, Xuechan Wang, Li Liao, Lei Yu, Wenwen Wu
  • Patent number: 12270745
    Abstract: A single pulse spectral statistical analysis method for particle size distribution of inclusions on a surface of a metal material is provided.
    Type: Grant
    Filed: July 24, 2024
    Date of Patent: April 8, 2025
    Assignees: NCS Testing Technology Co., Ltd., NCS Jiangsu Testing Technology Co., Ltd.
    Inventors: Yunhai Jia, Liang Sheng, Lei Yu, Liangjing Yuan, Shanshan Xu
  • Patent number: 12270819
    Abstract: An ultra-high-speed fully automatic precision spectral analysis system for rare earth metals and its working method is disclosed. The system includes a central control server, a precision numerical control rotary table communicatively connected with the central control server, a sample loading-clamping device, an automatic weighing device, an automatic ranging device, an analyzing surface machining device, a rare-earth spark emission spectrometer, and an automatic marking device; the sample loading-clamping device is arranged to fix a test sample of a rare earth metal, the automatic weighing device is arranged to weigh the test sample in real time, and the automatic ranging device, the analyzing surface machining device, the rare-earth spark emission spectrometer, and the automatic marking device are set up around the precision numerical control rotary table to perform the corresponding work processes respectively.
    Type: Grant
    Filed: March 7, 2024
    Date of Patent: April 8, 2025
    Assignee: NCS Testing Technology CO., LTD
    Inventors: Yunhai Jia, Liangjing Yuan, Lei Yu, Chunyan Zhang, Qiaochu Zhang, Shaoyin Li, Cheng Jin, Xiaoke Hao
  • Publication number: 20250105314
    Abstract: The present disclosure relates to a fin structure for a radiator, comprising a plurality of elongated fins arranged in parallel and spaced apart from each other, wherein an air flow channel is defined between opposing main side surfaces of adjacent two fins for allowing cooling air to flow therethrough along a fin longitudinal direction; a corrugated section extending in the fin longitudinal direction is formed on each fin; and the fins are arranged such that for adjacent fins, the peaks of the corrugated sections are aligned in the arranging direction of the fins and troughs of the corrugated sections are aligned in the arranging direction of the fins, characterized in that, in each wavy unit of the corrugated section, the wave peak is offset from a central plane between two adjacent wave troughs and approaches an inclined slope extending between a wave peak and a wave trough in an adjacent wavy unit of a corrugated section of an adjacent fin.
    Type: Application
    Filed: September 20, 2024
    Publication date: March 27, 2025
    Applicant: Caterpillar Inc.
    Inventors: Lei YU, Gengxin Liu, Guoping Tian, Guanqing Guo, Yuerou Wang
  • Publication number: 20250102244
    Abstract: The present disclosure relates to a composite fin structure for a radiator, comprising a plurality of elongated corrugated fins arranged in parallel and spaced apart from each other. Air flow channels are defined between the opposing main side surfaces of adjacent fins, allowing cooling air to flow therethrough along a longitudinal direction of the fins. It is characterized in that each fin comprises a first corrugated fin section having a first waveform and a second corrugated fin section having a second waveform, with extending directions of the first and second waveforms being consistent with the longitudinal direction of the fin. A fin density of the first waveform is greater than that of the second waveform, and the first corrugated fin section extend at least in an inlet side region of each air flow channel. This invention also relates to a radiator with the composite fin structure, as well as a fuel cell cooling system comprising the radiator.
    Type: Application
    Filed: September 19, 2024
    Publication date: March 27, 2025
    Applicant: Caterpillar Inc.
    Inventors: Lei YU, Gengxin LIU, Guoping TIAN, Yumei WANG, Yuerou WANG
  • Publication number: 20250085014
    Abstract: Disclosed is a temperature controller, a server, an air conditioning system and a temperature setting method. The temperature controller may be configured to operate in a carbon saving mode, and when operating in the carbon saving mode, the set temperature of the temperature controller is adjusted according to a green electricity index, and the green electricity index is the proportion of green electricity in a power grid to which the temperature controller is connected. When the proportion of the green electricity is high, i.e., the electric energy used is mainly from renewable energy sources, the set temperature is adjusted to produce more cold energy or heat energy for storage; and when the green electricity index decreases, the stored cold energy or heat energy can be used to meet the demand for cooling or heating, thereby reducing carbon emissions.
    Type: Application
    Filed: September 14, 2023
    Publication date: March 13, 2025
    Inventors: Qian Li, Yuhui Kuang, Tiejun Wu, Runfu Shi, Hongsheng Liu, Xinyi Gao, Xin Liang, Yingchao Jiang, Lei Yu
  • Publication number: 20250085012
    Abstract: This application aims to provides a method for controlling an air conditioning system, an air conditioning system, a computer-readable storage medium, a mobile terminal device and a server so as to at least solve or alleviate part of the problems in the prior art. In the first aspect, this application provides a method for controlling an air conditioning system, the air conditioning system including a plurality of indoor units arranged in different regions. The control method includes: a step for acquiring occupancy information, acquiring occupancy information of the region; a step for acquiring electric energy information, acquiring electric energy information containing an electric energy characteristic; and a step for generating an energy storage instruction, generating an energy storage instruction for a specific region on the basis of the occupancy information when the electric energy information satisfies a predetermined energy storage condition.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 13, 2025
    Inventors: Tiejun Wu, Lei Yu, Runfu Shi, Hongsheng Liu, Yuhui Kuang, Wei Huang
  • Publication number: 20250075933
    Abstract: A building chiller/heat pump system includes a chiller/heat pump system for supplying a conditioned fluid to change a temperature of air being delivered into a building. The chiller/heat pump system is provided with a control to achieve a desired setpoint of the air delivered into the building. The control is programmed to receive a prediction of expected remission levels in energy that will be delivered to power the chiller/heat pump system. The control is programmed to change the setpoint such that an energy level required to operate the chiller/heat pump system to achieve the setpoint will drop when the expected emissions level increases, and adjusts the setpoint in an opposed direction when the expected emissions drops. A method is also disclosed.
    Type: Application
    Filed: August 28, 2024
    Publication date: March 6, 2025
    Inventors: Wei Huang, Lei Yu, Claus Daniel, Stella Maris Oggianu, Runfu Shi, Guy DeLuca, Mark Makwinski, Rebecca Shen, Mann-Fai Yip, Shaw Ping Lee, Chai Kheh Chew
  • Publication number: 20250038254
    Abstract: An electrochemical apparatus includes a positive electrode, a negative electrode, a separator disposed between the positive electrode and the negative electrode, and an electrolyte. The negative electrode includes a negative electrode current collector and a negative electrode active material layer disposed on a surface of the negative electrode current collector, where the negative electrode active material layer includes a negative electrode binder with structural formula I. In the technical solution of this application, the negative electrode binder has the structural formula I, which provides a large number of lithium ion exchange sites to enhance ionic conductivity of the negative electrode binder, thereby improving fast charging performance and discharging performance of the electrochemical apparatus in a low-temperature environment.
    Type: Application
    Filed: September 30, 2024
    Publication date: January 30, 2025
    Applicant: Ningde Amperex Technology Limited
    Inventor: Lei Yu
  • Publication number: 20250027531
    Abstract: This application provides a hinge mechanism and an electronic device. One example hinge mechanism includes a base, and a first rotating assembly and a second rotating assembly that are respectively disposed on two sides of the base. When the first rotating assembly and the second rotating assembly rotate toward each other, a length of the hinge mechanism may be increased; or when the first rotating assembly and the second rotating assembly rotate opposite to each other, a length of the hinge mechanism may be shortened, and a support surface for supporting a flexible display can be formed.
    Type: Application
    Filed: October 3, 2024
    Publication date: January 23, 2025
    Inventors: Hewen SHEN, Wen FAN, Ding ZHONG, Li LIAO, Xuechan WANG, Lei YU
  • Patent number: 12202792
    Abstract: A preparation method for optically active citronellal, which can obviously enhance the catalytic stability of an optically active transition metal catalyst for asymmetric hydrogenation of homogeneous catalysis and thereby achieve higher turnover numbers. In the preparation method for optically active citronellal, a substrate is subjected to an asymmetric hydrogenation reaction in the presence of the transition metal catalyst to generate the optically active citronellal, wherein the transition metal catalyst is obtained by reacting a transition metal compound with an optically active ligand containing two phosphorus atoms, and the raw material of the substrate is one of neral and geranial or a combination thereof to control the hydroxyl value to be less than or equal to 6 mgKOH/g and/or the iron content to be less than or equal to 50 ppm in the raw material of the substrate for the asymmetric hydrogenation reaction.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: January 21, 2025
    Assignee: WANHUA CHEMICAL GROUP CO., LTD.
    Inventors: Jing Dong, Lei Yu, Yongzhen Zhang, Yuan Li
  • Patent number: 12203864
    Abstract: A spark spectrometry for inclusions content distribution on the surface of large size metallic materials, comprising the following steps: analyzing the surface of large-size metallic materials by spark discharge continuous excitation scanning, obtaining a mixture intensity distribution data of the solid solution and inclusions of an element on the surface of the large-size metallic materials; the relative frequency distribution diagram of spectral intensity is subjected to peak fitting of normal distribution and Gumbel distribution, obtaining an extreme value distribution data of spectral intensity of the inclusions; a size information of the inclusions in a small sample and that of the largest inclusions are correlated with the spectral intensity distribution data of inclusions, obtaining a result of content distribution of the inclusions on the surface of the large size metallic materials.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: January 21, 2025
    Assignee: NCS Testing Technology CO., LTD
    Inventors: Yunhai Jia, Liang Sheng, Liangjing Yuan, Lei Yu, Qiaochu Zhang
  • Patent number: D1084393
    Type: Grant
    Filed: August 2, 2024
    Date of Patent: July 15, 2025
    Inventors: Wu Zhan, Quanxin Yun, Zhentao Zhao, Lin Li, Yao Wang, Lei Yu, Yuxiang Li, Yuliang Dong, Wenwei Zhang, Yuning Zhang, Xun Xu
  • Patent number: D1084394
    Type: Grant
    Filed: August 2, 2024
    Date of Patent: July 15, 2025
    Inventors: Wu Zhan, Quanxin Yun, Zhentao Zhao, Lin Li, Yao Wang, Lei Yu, Yuxiang Li, Yuliang Dong, Wenwei Zhang, Yuning Zhang, Xun Xu