Abstract: The present disclosure provides compounds that can inhibit the type III secretion system (TTSS) to decrease the pathogenesis of gram-negative bacteria. These compounds may have wide applications for treating bacteria diseases caused by gram-negative bacteria in a host species, including but not limited to, plants and animals. The present invention further relates to compositions that inhibit pathogenesis of gram-negative bacteria without killing the bacteria. Methods relating to preventing and/or treating infection of a host species by bacterial pathogens are also provided herein.

Abstract: An electrocardio monitoring system and method are provided. The electrocardio monitoring system includes at least two sets of electrocardio channels and a processing circuit. Each of the at least two sets of electrocardio channels includes at least two electrodes, and each of the at least two sets of electrocardiographic channels is configured to collect signals from a human body through the at least two electrodes, respectively. The processing circuit is configured to extract the electrocardio signal from the signals collected by the at least two sets of electrocardiographic channels.

Abstract: The present invention relates to salt forms of the Pim kinase inhibitor N—{(7R)-4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-3-yl}-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide, including methods of preparation thereof, and intermediates in the preparation thereof, where the compound is useful in the treatment of Pim kinase-related diseases such as cancer.

Abstract: Embodiments of the present disclosure disclose a signal measurement method and circuit, comprising: receiving a detection signal, the detection signal reflecting a difference between two contact impedances, each of which is a contact impedance between one of two electrodes and a human body, and the two electrodes being affixed to the human body and being configured to collect a physiological signal of the human body; and determining an indicator parameter value reflecting a quality of the physiological signal based on the detection signal. The signal measurement method and circuit provided in the present disclosure can detect the contact impedance between each of the two electrodes and the human body in real-time, and determine, based on the contact impedance, state between each of the two electrodes and the human body, and thus ensure that a physiological signal collected by the electrodes have a high quality.

Abstract: An energy storage cabinet includes a cabinet, which comprises a cabinet body and an opening and closing door, where the cabinet body defines an installation cavity with one end open, a first space and a second space are formed in the installation cavity, the opening and closing door is used for opening or closing the installation cavity. The cabinet also includes a plurality of energy storage modules, the energy storage modules being arranged in the first space, the energy storage modules being stacked in a first direction of the energy storage cabinet, the first space and the second space being arranged side by side in a second direction perpendicular to the first direction; and a control unit, the control unit being arranged in the second space and the control unit is electrically connected to the energy storage module.

Abstract: An energy storage module and an energy storage cabinet. The energy storage module includes: an energy storage unit, the energy storage unit including a plurality of cells, and the plurality of cells being arranged in sequence in the thickness direction of the cells; a first side plate and a second side plate, the energy storage unit being provided between the first side plate and the second side plate; and support beams, the support beams extending in the thickness direction of the cells and being connected between the first side plate and the second side plate so as to enable the first side plate and the second side plate to clamp the energy storage unit, and the support beams being arranged on at least one side of the energy storage unit in the width direction of the cells.

Abstract: An energy storage cabinet includes: a cabinet, and a first space and a second space formed in the cabinet. Multiple battery modules are disposed in the first space and stacked in a first direction of the energy storage cabinet, and the first space and the second space are disposed side by side in a second direction of the energy storage cabinet perpendicular to the first direction. A controller disposed in the second space and electrically connected to the battery modules.

Abstract: The present application provides an information processing method, an access method, an apparatus and a storage medium. The method includes: receiving a physical uplink shared channel of a message A transmitted by a terminal; and determining a type of the terminal according to the physical uplink shared channel of the message A, to realize the identification of the type of the terminal in a random access procedure.

Abstract: Provided are a method and device employing a smart contract to realize identity-based key management. The method comprises: running a smart contract, and executing a key management process, wherein the key management process comprises: when a key of a target user requires an update and the target user is not a supervised user, generating a master public key and a master private key pertaining to the target user; acquiring, from a blockchain, identity information of the target user; generating a first target private key according to the master public key and the master private key pertaining to the target user and the identity information of the target user; and replacing a current private key of the target user with the first target private key.

Abstract: Disclosed is a pre-combustion chamber igniter, a methanol engine and a cold start control method thereof. The pre-combustion chamber igniter includes a housing, nozzles, a fuel injector, a spark plug and heating elements. The heating elements at outer surfaces of the nozzles can heat fuel spray sprayed to an inner wall of a pre-combustion chamber. According to the present disclosure, the pre-combustion chamber is heated using the heating elements during a cold start of the methanol engine, and an excess air coefficient of an interior of the pre-combustion chamber can be controlled between 0.8 and 1.0 to achieve ultra-lean combustion of the engine in a cold start state.

Abstract: This application discloses a network device-based data processing method and a network device, and may be applied to the field of memory access. A control unit (for example, a CPU) of a first computer device constructs an orchestration operator based on execution logic of a request generated by an application. The first computer device only needs to send the orchestration operator to a first network device for one time via the control unit, and the first network device performs parsing based on the orchestration operator, to obtain a corresponding memory access operation. After all memory access operations are completed, the first network device reports a completion instruction to the control unit. In this application, the constructed orchestration operator is used to execute user-programmable logic, to reduce a quantity of interactions between the first computer device and the first network device.

Abstract: A manifold assembly includes a liquid inlet pipe, a plurality of transparent windows and a liquid return pipe. The liquid inlet pipe has a first accommodating space, a first liquid inlet, a plurality of first liquid outlets and a plurality of openings. The first accommodating space is configured to accommodate a cooling liquid, and is in fluid communication with the first liquid inlet, the first liquid outlets and the openings. The transparent windows cover the openings. The cooling liquid is visible from outside via the transparent windows. The liquid return pipe has a second accommodating space, a plurality of second liquid inlets and a second liquid outlet. The second accommodating space is configured to accommodate a cooling liquid, and is in fluid communication with the second liquid inlets and the second liquid outlet.

Abstract: The present disclosure discloses an implant packaging bottle, which includes a bottle body; a bottle cap, wherein the bottle cap has a bottle cap body detachably connected with one end of the bottle body and an implant support frame configured to extend into the bottle body; an electrified base, which is provided at the other end of the bottle body; an implant bracket detachably connected to the implant support frame, wherein the implant can be installed on the implant bracket; and an ultraviolet light source configured to be provided in the bottle body, wherein the ultraviolet light source is electrically connected to the electrified base, and a plurality of ultraviolet light sources are provided; and when the implant support frame is extended into the bottle body, a plurality of ultraviolet light sources are provided around the implant on the implant bracket.

Abstract: An electrode (100), an electrophysiology catheter (200) and an ablation system are disclosed. The electrode (100) is configured to be disposed at a distal end of a catheter (200) and includes a proximal electrode portion (110), a main electrode portion (120) and a distal electrode portion (130), which are sequentially joined together from a proximal end to a distal end of the electrode. The main electrode portion (120) includes a first section (121) and a second section (122), which are joined to each other along an axis of the catheter (200). At least one of the proximal electrode portion (110) and the distal electrode portion (130) is configured to be movably connected to the catheter (200). The main electrode portion (120) is configured to switch between a contracted configuration and a folded configuration along with relative movement of the proximal electrode portion (110) and the distal electrode portion (130) along the catheter (200).

Abstract: A preparation method for glufosinate or a salt, an enantiomer or a mixture of enantiomers in all ratios thereof, the method being especially suitable for the preparation of glufosinate, and greatly shortening steps in an existing preparation process. Especially in the preparation of L-glufosinate, the product can effectively retain the ee value of the raw materials.

Abstract: Described herein are methods of purifying nucleic acids (e.g., mRNAs) from feed solutions using continuous, multicolumn chromatography approaches. Also described are methods of increasing the efficiency of chromatography methods by performing purification methods in parallel using multiple columns.

Abstract: Embodiments of the present disclosure provide method and apparatus for Designated Router (DR) seamless switchover. A method performed by a network device comprises detecting a DR failure event due to a failure DR. The method further comprises detecting that the second edge device is unreachable. The method further comprises holding refresh of router-Link State Advertisements (router-LSA) in a link-state database and flooding procedure, when a Backup Designated Router (BDR) has not declared to be a working DR in an Open Shortest Path First (OSPF) network.

Abstract: The present invention provides an anti-OX40 antibody or antigen-binding fragment thereof, a preparation method therefor and the use for treating OX40-related diseases or conditions.

Abstract: Systems, apparatuses, and methods are described for deploying upstream bandwidth upgrade of devices per home basis. The impact of the upstream bandwidth upgrade on the devices may be pre-estimated based on remotely monitoring and/or analyzing performance data of the devices collected during transmissions of test signals (e.g., a burst of upstream transmissions) in real-time from the devices operating under different modes of operations. The burst of upstream transmissions using a small bandwidth (e.g., 1.6 MHz) may be limited to a short duration of time (e.g., 5 seconds) so that on-going services provided by the devices are not substantially interrupted. The upstream bandwidth of the devices, based on the pre-estimated impact, may be upgraded, left unaltered, or downgraded.

Abstract: An optical wavelength measurement apparatus and method may be used to expand a wavelength range that can be detected by using an optical wavelength measurement technology. The measurement apparatus may respectively superimpose to-be-measured light with optical components that are in an optical frequency comb and that correspond to each of a plurality of comb frequency values, to obtain a multiplexed optical signal corresponding to each optical component, and then determine a measured value of a wavelength of the to-be-measured light based on an electrical signal of a multiplexed optical signal corresponding to a target optical component obtained by an electrical beat frequency. The electrical signal corresponding to the target optical component includes a beat frequency signal.