Abstract: An ultrasonic imaging method includes: generating and displaying a first contrast enhanced image in real time under a normal contrast enhanced mode; switching from the normal contrast enhanced mode to a super-resolution contrast enhanced imaging mode, obtaining second ultrasonic echo signals to generate and display a second contrast enhanced image, and performing super-resolution data processing on the second ultrasonic echo signals to obtain a super-resolution image when displaying the second contrast enhanced image; and displaying the super-resolution image. The present disclosure can generate and display the second contrast enhanced image when collecting the ultrasonic echo signals used for super-resolution data processing, so that it is convenient for users to observe the current state of microbubble perfusion to enable the users to observe and compare the super-resolution image and the second contrast enhanced image, obtaining more diagnostic information.

Abstract: The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is Cl, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is Cl, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

Abstract: Embodiments are directed to improving remote traffic performance on cluster-aware processors. An embodiment of a system includes at least one processor package comprising a plurality of processor ports and a plurality of system agents; and a memory device to store platform initialization firmware to cause the processing system to: determine first locations of the plurality of processor ports in the at least one processor package; determine second locations of the plurality of system agents in the at least one processor package; associate each of the processor ports with a set of the plurality of system agents based on the determined first and second locations; and program the plurality of system agents with the associated processor port for the respective system agent.

Abstract: A 3D ultrasound imaging device including an ultrasound probe assembly and echo analyzer. The ultrasound probe assembly includes a housing and an acoustic window abutted against the housing to form a sealed chamber, wherein the surface of the acoustic window contacts with the breast of the human body to be examined; an ultrasound transducer moves at a first speed back and forth within the sealed chamber and performs high-speed pre-scanning through the acoustic window to obtain initial ultrasound signals; the echo analyzer analyzes the initial ultrasound signals to determine a quality of a ultrasound image acquired by the high speed pre-scanning; and the ultrasound transducer then moves at a second speed to perform another scan to acquire new ultrasound signals. A 3D ultrasound imaging method is also disclosed.

Abstract: The present invention discloses a packaging structure of a high-power radio frequency device, comprising a plurality of radio frequency power chips connected in parallel and a packaging flange; and the plurality of radio frequency power chips are arranged obliquely in a packaging cavity of the packaging flange, to reduce the number of input bond-wires of the radio frequency power chips, so that the input bond-wires and output bond-wires are not overlapped in space. The plurality of chips are arranged obliquely on the packaging flange, which significantly improves the utilization rate of packaging space and achieves the purpose of high-power output.

Abstract: The present disclosure relates to a human FGF21 mutant with improved effectiveness and stability, preparation method and pharmaceutical composition comprising the mutant, and a use thereof, and specifically relates to a human fibroblast growth factor 21 (FGF21) mutant, a gene encoding the same, and a method for preparing the mutant and a method of using the mutant for treating type 2 diabetes, obesity, dyslipidemia, or metabolic disorders.

Abstract: The present disclosure relates to crystalline forms of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one hemihydrate (Compound 1) and/or tautomers thereof, wherein Compound 1 has the structure: (I)·0.5H2O; processes for preparing crystalline forms of Compound 1 and/or tautomers thereof; pharmaceutical compositions comprising the crystalline forms; methods of inhibiting a cell division cycle 7 in a mammal comprising administering the crystalline forms; and methods of treating a cell division cycle 7 mediated cancer in a mammal comprising administering the crystalline forms or a pharmaceutical composition comprising the crystalline forms.

Abstract: Embodiments of the present disclosure provide a contrast enhanced ultrasound imaging method and an ultrasound imaging device. The method may include: determining a target imaging mode from preset imaging modes in response to the first instruction, where the preset imaging modes comprise a first contrast enhanced imaging mode and a second contrast enhanced imaging mode which have different frame rate; transmitting ultrasound waves to a target object and receiving ultrasound echoes returned from the target object according to the determined target imaging mode to obtain ultrasound echo signals; and generating a contrast enhanced image according to the ultrasound echo signals. An ultrasound imaging device is also be provided.

Abstract: Embodiments of the present disclosure are directed to systems and methods for managing attachment requests for UEs in a wireless network environment comprising a first set of base stations and a second set of base stations when the first and second set of base stations have at least one unique network characteristic. By rejecting attachment requests to UEs attempting to access one or more base stations of the second set of base stations, the conventional cell selection and attachment process will drive UEs to attach to the first set of base stations.

Abstract: A composite material structure includes a first metal member and a second metal member bonding to the first metal member. A bonding surface is formed therebetween. A first hole is through the first metal member. A circular bonding line is formed at a junction of a wall of the first hole and the bonding surface. A sleeve protrudes from the second metal member into the first hole, and covers the bonding line. A groove indents from the first metal member. The groove has a bottom surface located in the same plane with a top surface of the sleeve. A processing method of the composite material structure is also provided. The sleeve covers the bonding line between the first metal member and the second metal member, which allows the composite material structure to provide an improved sealing performance.

Abstract: A voltage generating circuit includes a first transistor and a second transistor. Voltage of a substrate of the first transistor varies with a first parameter. The first parameter is any one of a supply voltage, an operating temperature, as well as a manufacturing process of the voltage generating circuit. A gate of the first transistor is connected to a drain of the first transistor. The substrate of the first transistor serves as an output of the voltage generating circuit. A gate of the second transistor is connected to a drain of the second transistor.

Abstract: Disclosed are photoacoustic imaging systems, and laser energy correction methods and prompting methods therefor, and photoacoustic imaging systems.

Abstract: Embodiments of the present disclosure provide a contrast enhanced ultrasound imaging method and an ultrasound imaging device. The method may include: determining a target imaging mode from preset imaging modes in response to the first instruction, where the preset imaging modes comprise a first contrast enhanced imaging mode and a second contrast enhanced imaging mode which have different frame rate; transmitting ultrasound waves to a target object and receiving ultrasound echoes returned from the target object according to the determined target imaging mode to obtain ultrasound echo signals; and generating a contrast enhanced image according to the ultrasound echo signals. An ultrasound imaging device is also provided.

Abstract: Systems, apparatuses and methods may provide for technology that initializes a host-managed device memory (HDM) as a temporary proxy for a system memory, wherein the HDM is associated with an accelerator. The technology also creates a shadow copy of boot firmware code in the HDM and executes one or more boot instructions in the shadow copy of the boot firmware code. In one example, the one or more boot instructions are to be one or more of executed before an initialization of the system memory or executed in parallel with the initialization of the system memory.

Abstract: The present disclosure relates to a dual-band antenna array with fan beam and pencil beam. The antenna comprises a substrate and an antenna array arranged on the surface of the substrate, a first antenna element and a second antenna element are cascaded in an x-axis direction by a filter phase-shift line so as to form a subarray. A pair of T-shaped monopoles are symmetrically placed along the x axis at a certain distance above and below each of the first and second antenna elements, respectively, and a rectangular slot is embedded in the upper edge of the second antenna element to achieve good impedance matching. The second antenna element generates a fan beam at one frequency point or frequency band to have the performance of a wide beam, and generates a pencil beam at another frequency point or frequency band to have the performance of a narrow beam.

Abstract: The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is Cl, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is Cl, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed are 3D/4D contrast-enhanced ultrasound imaging (CEUS) apparatus, 3D/4D CEUS imaging methods and media. The method comprises: receiving an input for selecting a 3D/4D contrast-enhanced imaging mode; receiving an input for setting an imaging velocity including a first imaging velocity and a higher second imaging velocity; controlling the apparatus with an imaging parameter associated with the selected imaging mode and the set imaging velocity to achieve imaging with the selected imaging mode in the set imaging velocity, wherein an association between the imaging parameter and the imaging velocity allows that an amount of data required to generate images per volume using the first imaging velocity is greater than that using the second imaging velocity. In this way, a desired imaging mode and imaging velocity can be chosen freely and an imaging parameter can be selected pointedly, meeting real-time observation needed by doctors with limited data processing capability and various probes.

Abstract: Disclosed are methods and apparatus for viewing a contrast-enhanced ultrasound image and a dynamic data. The method comprises: receiving a first operation, for setting a first viewing range by a first browsing step length that is multiple frames; in response to the first operation, positioning the image data to a viewing neighborhood containing the first viewing range; receiving a second operation, on the view neighborhood by a second browsing step length that is a single frame; in response to the second operation, determining a current image frame corresponding to when the second operation is performed in the viewing neighborhood, and further positioning the image data to an adjacent frame of the current image frame to the user to view frame by frame. As such, doctors are helped to accurately locate desired image frames to significantly improve browsing efficiency with convenient operation and high user-friendliness to save time and reduce workload.

Abstract: The present disclosure relates to crystalline forms of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one hemihydrate (Compound 1) and/or tautomers thereof, wherein Compound 1 has the structure: (I).0.5H2O; processes for preparing crystalline forms of Compound 1 and/or tautomers thereof; pharmaceutical compositions comprising the crystalline forms; methods of inhibiting a cell division cycle 7 in a mammal comprising administering the crystalline forms; and methods of treating a cell division cycle 7 mediated cancer in a mammal comprising administering the crystalline forms or a pharmaceutical composition comprising the crystalline forms.