Patents by Inventor Leif Brand

Leif Brand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7345759
    Abstract: A device for the measurement of chemical and/or biological samples, in particular by means of luminescence spectroscopy, comprises an irradiation unit, a sample receiver, at least one optical unit and a detector unit. The color marker in the sample, which contains at least one color marker, is stimulated by irradiation into producing luminescence and gives off light. The light emitted by the color markers is detected by detectors in the detector unit. According to the invention, the measurement results may be improved by the irradiation unit generating pulsed irradiation. The irradiation unit is thus preferably controlled by a control unit in such a way that the irradiation pulses impinge on the sample in a temporal sequence.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: March 18, 2008
    Assignee: Evotec OAI AG
    Inventors: Rolf Guenther, Leif Brand, Christian Eggeling, Karsten Gall, Claus Seidel
  • Publication number: 20050164160
    Abstract: A device for the measurement of chemical and/or biological samples, in particular by means of luminescence spectroscopy, comprises an irradiation unit (12), a sample receiver (10), at least one optical unit (30) and a detector unit (40). Electromagnetic radiation of various wavelength ranges and/or polarizations are led from the sample (10) from the irradiation unit (12). The color marker in the sample (10), which contains at least one color marker, is stimulated into producing luminescence and gives off light. The emitted light is led by means of an optical unit to a detector unit. The light emitted by the color markers is detected by detectors (42, 44, 46, 48) in the detector unit. According to the invention, the measurement results may be improved on the irradiation unit (12) generating a pulsed irradiation. The irradiation unit is thus preferably controlled by a control unit (18) in such a way that the irradiation pulses impinge on the sample (10) in a temporal sequence.
    Type: Application
    Filed: August 22, 2001
    Publication date: July 28, 2005
    Inventors: Rolf Gunter, Leif Brand, Christian Eggeling, Karsten Gall, Claus Seidel
  • Patent number: 6137584
    Abstract: A method and device are disclosed for expanding the field of application of florescent correlation spectroscopy. The device has a confocal optical structure, a pulsed laser for excitation and components for detection and evaluation of measuring signals for time-correlated single photon counting. The data is registered in such a way that for each detected photon, detection time is recorded in microseconds while fluorescence delay time is recorded in nanoseconds. The information on each detected photon is used to assign parameters determined by time-correlated single photon counting to each detected photon and to create correlation functions from the determined parameters arising therefrom. Correlation functions of parameters or selective correlation functions, e.g. for fluorescence burning life, are thus obtained.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: October 24, 2000
    Assignees: Max-Planck-Gesellschaft Zur, Evotec BioSystems Aktiengesellschaft
    Inventors: Claus Seidel, Leif Brand, Rolf Gunther