Patents by Inventor Leif Salford

Leif Salford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING A MAMMAL SUFFERING FROM OR SUSCEPTIBLE TO AN IMMUNE REACTION TO DRUG TREATMENT
    Publication number: 20200078453
    Abstract: There is provided according to the invention a method of treating a mammal suffering from or susceptible to an immune reaction to drug treatment comprising the raising of anti-drug antibodies which method comprises (a) ex-vivo treating antigen presenting cells obtained from the mammal with an agent which induces IDO in said antigen presenting cells in the presence of said drug or an epitope containing fragment thereof and (b) after IDO has been induced in said antigen presenting cells, transferring said cells back to the mammal thereby to establish immune tolerance to the drug.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 12, 2020
    Inventors: Peter Ericsson, Lars Hedbys, Leif Salford, Hans-Olov Sjogren
  • METHODS OF INDUCING INDOLAMINE 2,3 - DIOXYGENASE (IDO)
    Publication number: 20180028621
    Abstract: A composition and method for using a composition, the composition having at least two compounds, each of which induces indolamine 2,3-dioxygenase, for the treatment of an autoimmune disorder or disease or immune rejection of transplants or gene therapeutically modified cells, wherein the inducers have different mechanism of action and wherein the composition gives rise to a synergistic effect on the IDO levels.
    Type: Application
    Filed: October 16, 2017
    Publication date: February 1, 2018
    Inventors: Leif Salford, Hans Olov Sjogren, Bengt Widegren
  • Methods of inducing indolamine 2,3—dioxygenase (IDO)
    Patent number: 9839674
    Abstract: A composition and method for using a composition, the composition having at least two compounds, each of which induces indolamine 2,3-dioxygenase, for the treatment of an autoimmune disorder or disease or immune rejection of transplants or gene therapeutically modified cells, wherein the inducers have different mechanism of action and wherein the composition gives rise to a synergistic effect on the IDO levels.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: December 12, 2017
    Assignee: Idogen AB
    Inventors: Leif Salford, Hans Olov Sjogren, Bengt Widegren
  • NOVEL TREATMENT METHOD
    Publication number: 20170014499
    Abstract: There is provided according to the invention a method of treating a mammal suffering from or susceptible to an immune reaction to drug treatment comprising the raising of anti-drug antibodies which method comprises (a) ex-vivo treating antigen presenting cells obtained from the mammal with an agent which induces IDO in said antigen presenting cells in the presence of said drug or an epitope containing fragment thereof and (b) after IDO has been induced in said antigen presenting cells, transferring said cells back to the mammal thereby to establish immune tolerance to the drug.
    Type: Application
    Filed: September 20, 2016
    Publication date: January 19, 2017
    Inventors: Peter Ericsson, Lars Hedbys, Leif Salford, Hans-Olov Sjogren
  • Composition Comprising At Least Two Compounds Which Induce Indolamine 2,3 - Dioxygenase (IDO), for the Treatment of an Autoimmune Disorder or Suffering from Immune Rejection of Organs
    Publication number: 20150182592
    Abstract: A composition and method for using a composition, the composition having at least two compounds, each of which induces indolamine 2,3-dioxygenase, for the treatment of an autoimmune disorder or disease or immune rejection of transplants or gene therapeutically modified cells, wherein the inducers have different mechanism of action and wherein the composition gives rise to a synergistic effect on the IDO levels.
    Type: Application
    Filed: November 25, 2014
    Publication date: July 2, 2015
    Inventors: Leif SALFORD, Hans Olov SJOGREN, Bengt WIDEGREN
  • COMPOSITION COMPRISING AT LEAST TO COMPOUNDS WHICH INDUCES INDOLAMINE 2,3 - DIOXYGENASE (IDO), FOR THE TREATMENT OF AN AUTOIMMUNE DISORDER OR SUFFERING FROM IMMUNE REJECTION OF ORGANS
    Publication number: 20130309198
    Abstract: A composition and method for using a composition, the composition having at least two compounds, each of which induces indolamine 2,3-dioxygenase, for the treatment of an autoimmune disorder or disease or immune rejection of transplants or gene therapeutically modified cells, wherein the inducers have different mechanism of action and wherein the composition gives rise to a synergistic effect on the IDO levels.
    Type: Application
    Filed: December 20, 2011
    Publication date: November 21, 2013
    Applicant: IDOGEN AB
    Inventors: Leif Salford, Hans Olov Sjogren, Bengt Widegren